292 research outputs found

    Two Stream Scene Understanding on Graph Embedding

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    The paper presents a novel two-stream network architecture for enhancing scene understanding in computer vision. This architecture utilizes a graph feature stream and an image feature stream, aiming to merge the strengths of both modalities for improved performance in image classification and scene graph generation tasks. The graph feature stream network comprises a segmentation structure, scene graph generation, and a graph representation module. The segmentation structure employs the UPSNet architecture with a backbone that can be a residual network, Vit, or Swin Transformer. The scene graph generation component focuses on extracting object labels and neighborhood relationships from the semantic map to create a scene graph. Graph Convolutional Networks (GCN), GraphSAGE, and Graph Attention Networks (GAT) are employed for graph representation, with an emphasis on capturing node features and their interconnections. The image feature stream network, on the other hand, focuses on image classification through the use of Vision Transformer and Swin Transformer models. The two streams are fused using various data fusion methods. This fusion is designed to leverage the complementary strengths of graph-based and image-based features.Experiments conducted on the ADE20K dataset demonstrate the effectiveness of the proposed two-stream network in improving image classification accuracy compared to conventional methods. This research provides a significant contribution to the field of computer vision, particularly in the areas of scene understanding and image classification, by effectively combining graph-based and image-based approaches

    Polymeric Janus nanorods via anodic aluminum oxide templating

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    We report a novel method for the fabrication of polymeric Janus nanorods via sequential polymerization from anodic aluminum oxide (AAO) templates. Dual compositions can be incorporated into individual nanorods and endow versatile potential applications. This fabrication strategy paves the way for constructing multifunctional nanostructures and brings together different materials in a single entity

    Mapping the tail fiber as the receptor binding protein responsible for differential host specificity of Pseudomonas aeruginosa bacteriophages PaP1 and JG004.

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    The first step in bacteriophage infection is recognition and binding to the host receptor, which is mediated by the phage receptor binding protein (RBP). Different RBPs can lead to differential host specificity. In many bacteriophages, such as Escherichia coli and Lactococcal phages, RBPs have been identified as the tail fiber or protruding baseplate proteins. However, the tail fiber-dependent host specificity in Pseudomonas aeruginosa phages has not been well studied. This study aimed to identify and investigate the binding specificity of the RBP of P. aeruginosa phages PaP1 and JG004. These two phages share high DNA sequence homology but exhibit different host specificities. A spontaneous mutant phage was isolated and exhibited broader host range compared with the parental phage JG004. Sequencing of its putative tail fiber and baseplate region indicated a single point mutation in ORF84 (a putative tail fiber gene), which resulted in the replacement of a positively charged lysine (K) by an uncharged asparagine (N). We further demonstrated that the replacement of the tail fiber gene (ORF69) of PaP1 with the corresponding gene from phage JG004 resulted in a recombinant phage that displayed altered host specificity. Our study revealed the tail fiber-dependent host specificity in P. aeruginosa phages and provided an effective tool for its alteration. These contributions may have potential value in phage therapy

    Polymeric Janus nanorods via anodic aluminum oxide templating

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    Isolation and identification of compounds present in rhizomes of Paris axialis H. Li and study of their cytotoxic effects

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    Ten compounds were isolated from the rhizomes of Paris axialis H. Li (PA). Based on spectral data, the isolated compounds were identified as Diosgenin (1), Paris saponin V (2), Paris saponin VI (3), Paris saponin I 4), Paris saponin H (5), Paris saponin II (6), Paris saponin VII (7), luteolin (8), luteoloside (9), isorhamnetin-3-O-α-L-rhamnopyranosyl (1→2)-β-D-glycopyranoside (10). Their cytotoxicity on LA795 cells was evaluated. Paris saponins and flavonoids have synergistic anti-tumor effect on LA795 cells.Colegio de Farmacéuticos de la Provincia de Buenos Aire

    Isolation and identification of compounds present in rhizomes of Paris axialis H. Li and study of their cytotoxic effects

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    Ten compounds were isolated from the rhizomes of Paris axialis H. Li (PA). Based on spectral data, the isolated compounds were identified as Diosgenin (1), Paris saponin V (2), Paris saponin VI (3), Paris saponin I 4), Paris saponin H (5), Paris saponin II (6), Paris saponin VII (7), luteolin (8), luteoloside (9), isorhamnetin-3-O-α-L-rhamnopyranosyl (1→2)-β-D-glycopyranoside (10). Their cytotoxicity on LA795 cells was evaluated. Paris saponins and flavonoids have synergistic anti-tumor effect on LA795 cells.Colegio de Farmacéuticos de la Provincia de Buenos Aire

    Anti-inflammatory effects of Fritillaria ussuriensis maxim

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    Bulbs of Fritillaria ussuriensis Maxim., usually known as Bulbus Fritillariae ussuriensis, (BFU) has been used as antitussive, antiasthmatic and expectorant in traditional herbal medicine. In this study, the aqueous extract of BFU (BFUE) was evaluated for its anti-inflammatory activity. Meanwhile, the content of PGE2 and MDA in inflammatory exudates was measured to explore the anti-inflammatory mechanisms of BFUE. In order to identify the active components of BFU, the total alkaloids (TA), the total flavonoids (TF) and the total saponins (TS) were evaluated for their bioactivities. Results showed that BFUE inhibited carrageenin-induced paw edema, xylene-induced auricular edema and acetic acid-induced vascular permeation in a dose-dependent manner, and it revealed obvious inhibitory effects on the increase of PGE2 and MDA. TF showed the highest anti-inflammatory effects on auricular edema induced by xylene in mice, and TS at a dose of 400 and 200 mg/kg also showed good effects (P 2 and MDA levels, and TF and TS might be the active components for this activity.Colegio de Farmacéuticos de la Provincia de Buenos Aire

    Anti-inflammatory effects of Fritillaria ussuriensis maxim

    Get PDF
    Bulbs of Fritillaria ussuriensis Maxim., usually known as Bulbus Fritillariae ussuriensis, (BFU) has been used as antitussive, antiasthmatic and expectorant in traditional herbal medicine. In this study, the aqueous extract of BFU (BFUE) was evaluated for its anti-inflammatory activity. Meanwhile, the content of PGE2 and MDA in inflammatory exudates was measured to explore the anti-inflammatory mechanisms of BFUE. In order to identify the active components of BFU, the total alkaloids (TA), the total flavonoids (TF) and the total saponins (TS) were evaluated for their bioactivities. Results showed that BFUE inhibited carrageenin-induced paw edema, xylene-induced auricular edema and acetic acid-induced vascular permeation in a dose-dependent manner, and it revealed obvious inhibitory effects on the increase of PGE2 and MDA. TF showed the highest anti-inflammatory effects on auricular edema induced by xylene in mice, and TS at a dose of 400 and 200 mg/kg also showed good effects (P 2 and MDA levels, and TF and TS might be the active components for this activity.Colegio de Farmacéuticos de la Provincia de Buenos Aire
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