11,265 research outputs found
On-demand or Spot? Selling the cloud to risk-averse customers
In Amazon EC2, cloud resources are sold through a combination of an on-demand
market, in which customers buy resources at a fixed price, and a spot market,
in which customers bid for an uncertain supply of excess resources. Standard
market environments suggest that an optimal design uses just one type of
market. We show the prevalence of a dual market system can be explained by
heterogeneous risk attitudes of customers. In our stylized model, we consider
unit demand risk-averse bidders. We show the model admits a unique equilibrium,
with higher revenue and higher welfare than using only spot markets.
Furthermore, as risk aversion increases, the usage of the on-demand market
increases. We conclude that risk attitudes are an important factor in cloud
resource allocation and should be incorporated into models of cloud markets.Comment: Appeared at WINE 201
Acclimation of morphology and physiology in turf grass to low light environment: A review
This short review elucidated the significance of the research on acclimation of the morphology and physiology in turf grass to low light environment, the mechanism of physiological response and the photosynthetic regulation and control of turf grass to suit low light environment. We also discussed current research problems and provided insight into future relevant research.Key words: Low light, morphological change, physiological acclimation, regulation mechanism, turf grass
A Prediction Model for the Calculation of Effective Stiffness Ratios of Reinforced Concrete Columns
Nonlinear dynamic analyses of reinforced concrete (RC) frame buildings require the use of effective stiffness of members to capture the effect of cracked section stiffness. In the design codes and practices, the effective stiffness of RC sections is given as an empirical fraction of the gross stiffness. However, a more precise estimation of the effective stiffness is important as it affects the distribution of forces and various demands and response parameters in nonlinear dynamic analyses. In this study, an evolutionary computation method called gene expression programming (GEP) was used to predict the effective stiffness ratios of RC columns. Constitutive relationships were obtained by correlating the effective stiffness ratio with the four mechanical and geometrical parameters. The model was developed using a database of 226 samples of nonlinear dynamic analysis results collected from another study by the author. Subsequent parametric and sensitivity analyses were performed and the trends of the results were confirmed. The results indicate that the GEP model provides precise estimations of the effective stiffness ratios of the RC frame
Ascaroside Expression in Caenorhabditis elegans Is Strongly Dependent on Diet and Developmental Stage
Background:
The ascarosides form a family of small molecules that have been isolated from cultures of the nematode Caenorhabditis elegans. They are often referred to as “dauer pheromones” because most of them induce formation of long-lived and highly stress resistant dauer larvae. More recent studies have shown that ascarosides serve additional functions as social signals and mating pheromones. Thus, ascarosides have multiple functions. Until now, it has been generally assumed that ascarosides are constitutively expressed during nematode development.
Methodology/Principal Findings:
Cultures of C. elegans were developmentally synchronized on controlled diets. Ascarosides released into the media, as well as stored internally, were quantified by LC/MS. We found that ascaroside biosynthesis and release were strongly dependent on developmental stage and diet. The male attracting pheromone was verified to be a blend of at least four ascarosides, and peak production of the two most potent mating pheromone components, ascr#3 and asc#8 immediately preceded or coincided with the temporal window for mating. The concentration of ascr#2 increased under starvation conditions and peaked during dauer formation, strongly supporting ascr#2 as the main population density signal (dauer pheromone). After dauer formation, ascaroside production largely ceased and dauer larvae did not release any ascarosides. These findings show that both total ascaroside production and the relative proportions of individual ascarosides strongly correlate with these compounds' stage-specific biological functions.
Conclusions/Significance:
Ascaroside expression changes with development and environmental conditions. This is consistent with multiple functions of these signaling molecules. Knowledge of such differential regulation will make it possible to associate ascaroside production to gene expression profiles (transcript, protein or enzyme activity) and help to determine genetic pathways that control ascaroside biosynthesis. In conjunction with findings from previous studies, our results show that the pheromone system of C. elegans mimics that of insects in many ways, suggesting that pheromone signaling in C. elegans may exhibit functional homology also at the sensory level. In addition, our results provide a strong foundation for future behavioral modeling studies
Migration patterns and winter population dynamics of rice planthoppers in Indochina: New perspectives from field surveys and atmospheric trajectories
This is the author accepted manuscript. The final version is available from Elsevier Masson via the DOI in this record.Rice planthoppers (RPH) are the most serious insect pests of rice production in East Asia, frequently out-breaking in China, Korea and Japan each summer. They are unable to overwinter in temperate East Asia, and summer populations arise anew each year via northward spring migration from south-east Asia. The annual migration cycle is generally believed to be a closed loop with mass returns to south-east Asia in the autumn, but this leg of the journey and the overwintering dynamics are much less studied than the spring immigrations. Previous studies have indicated that the north-central Vietnam (NCV) region is a key location for both the spring colonisation of China and for receiving return migrants from southern China each autumn. However, NCV experiences a three-month rice-free fallow period during mid-winter, and so it cannot be the principal over-wintering region for RPH populations. In this study, the continental-scale migration patterns of RPH in East Asia were explored using data from light trap catches, field surveys and atmospheric trajectory simulations. Our results confirmed that large numbers of return migrants arrive in NCV from southern China each autumn, but that they are unable to survive there over winter. The NCV region is recolonised in the early-spring (mid-February to mid-March) of each year by migrants from winter rice-growing regions in north-east Thailand, southern Laos and south-central coastal Vietnam, which are transported on favourable high-altitude synoptic winds. The following generation initiates the colonisation of East Asia from a large source population in NCV. Our results provide a new perspective on RPH migration patterns and over-wintering dynamics in East Asia, which is governed by crop production, environmental conditions and synoptic wind patterns at a continental scale.National Natural Science Foundation of China (NSFC)Natural Science Foundation of Jiangsu ProvinceBiotechnology and Biological Sciences Research Council (BBSRC)Science and Technology Facilities Council (STFC
Urban Birth, Urban Living, and Work Migrancy: Differential Effects on Psychotic Experiences Among Young Chinese Men
BACKGROUND: Urban birth and urban living are associated with increased risk of schizophrenia but less is known about effects on more common psychotic experiences (PEs). China has undergone the most rapid urbanization of any country which may have affected the population-level expression of psychosis. We therefore investigated effects of urbanicity, work migrancy, and residential stability on prevalence and severity of PEs. METHODS: Population-based, 2-wave household survey of psychiatric morbidity and health-related behavior among 4132 men, 18-34 years of age living in urban and rural Greater Chengdu, Sichuan Province, China. PEs were measured using the Psychosis Screening Questionnaire. RESULTS: 1261 (31%) of young men experienced at least 1 PE. Lower levels of PEs were not associated with urbanicity, work migrancy or residential stability. Urban birth was associated with reporting 3 or more PEs (OR: 1.63; 95% CI: 1.25-2.11), after multivariable adjustment, with further evidence (P = .01) this effect was restricted to those currently living in urban environments (OR: 1.78; 95% CI: 1.16-2.72). Men experiencing a maximum of 5 PEs were over 8 times more likely to have been born in an urban area (adjusted odds ratio [AOR] 8.81; 95% CI 1.50-51.79). CONCLUSIONS: Men in Chengdu, China, experience a high prevalence of PEs. This may be explained by rapid urbanization and residential instability. Urban birth was specifically associated with high, but not lower, severity levels of PEs, particularly amongst those currently living in urban environments. This suggests that early and sustained environmental exposures may be associated with more severe phenotypes
Effects of nocturnal celestial illumination on high-flying migrant insects
This is the final version. Available on open access from the Royal Society via the DOI in this recordData accessibility: Data are available from the Dryad Digital repository: https://doi.org/10.5061/dryad.sn02v6xb5 [53].Radar networks hold great promise for monitoring population trends of migrating insects. However, it is important to elucidate the nature of responses to environmental cues. We use data from a mini-network of vertical-looking entomological radars in the southern UK to investigate changes in nightly abundance, flight altitude and behaviour of insect migrants, in relation to meteorological and celestial conditions. Abundance of migrants showed positive relationships with air temperature, indicating that this is the single most important variable influencing the decision to initiate migration. In addition, there was a small but significant effect of moonlight illumination, with more insects migrating on full moon nights. While the effect of nocturnal illumination levels on abundance was relatively minor, there was a stronger effect on the insects' ability to orientate close to downwind: flight headings were more tightly clustered on nights when the moon was bright and when cloud cover was sparse. This indicates that nocturnal illumination is important for the navigational mechanisms used by nocturnal insect migrants. Further, our results clearly show that environmental conditions such as air temperature and light levels must be considered if long-term radar datasets are to be used to assess changing population trends of migrants.National Natural Science Foundation of Chin
Refractive change following pseudophakic vitrectomy: a retrospective review
Background
To assess the occurrence and magnitude of refractive change in pseudophakic eyes undergoing 20 gauge pars plana vitrectomy without scleral buckling and to investigate possible aetiological factors.
Methods
Retrospective case note review of 87 pseudophakic eyes undergoing 20 gauge pars plana vitrectomy for a variety of vitreo-retinal conditions over a three-year period. Anterior chamber depth (ACD) was measured before and after vitrectomy surgery in 32 eyes. Forty-three pseudophakic fellow eyes were used as controls.
Results
Eighty-seven eyes (84 patients) were included in the study. Mean spherical equivalent refraction prior to vitrectomy was -0.20 dioptres, which changed to a mean of -0.65 dioptres postoperatively (standard deviation of refractive change 0.59, range-2.13 to 0.75 dioptres) (p < 0.001). Sixty-one of the 87(70%) eyes experienced a myopic shift and 45(52%) eyes had a myopic shift of -0.5 dioptres or more. Mean fellow eye refraction was -0.19 dioptres preoperatively and -0.17 dioptres postoperatively (p = 0.14)(n = 37) Mean ACD preoperatively was 3.29 mm and postoperatively 3.27 mm (p = 0.53) (n = 32) and there was no significant change in ACD with tamponade use. Regression analysis revealed no statistically significant association between changes in anterior chamber depth, as well as a wide variety of other pre-, intra and postoperative factors examined, and the refractive change observed.
Conclusion
Significant refractive changes occur in some pseudophakic patients undergoing 20 g pars plana vitrectomy. The mean change observed was a small myopic shift but the range was large. The aetiology of the refractive change is uncertain
In situ evidence for the structure of the magnetic null in a 3D reconnection event in the Earth's magnetotail
Magnetic reconnection is one of the most important processes in
astrophysical, space and laboratory plasmas. Identifying the structure around
the point at which the magnetic field lines break and subsequently reform,
known as the magnetic null point, is crucial to improving our understanding
reconnection. But owing to the inherently three-dimensional nature of this
process, magnetic nulls are only detectable through measurements obtained
simultaneously from at least four points in space. Using data collected by the
four spacecraft of the Cluster constellation as they traversed a diffusion
region in the Earth's magnetotail on 15 September, 2001, we report here the
first in situ evidence for the structure of an isolated magnetic null. The
results indicate that it has a positive-spiral structure whose spatial extent
is of the same order as the local ion inertial length scale, suggesting that
the Hall effect could play an important role in 3D reconnection dynamics.Comment: 14 pages, 4 figure
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