Juries and Justice: Are Malpractice and Other Personal Injuries Created Equal?

A study analyzed the civil jury system and the difference in personal injury awards between automobile and deep-pocket defendants, especially in medical malpractice cases. Six conclusions were reached, including the finding that juries sometimes respond emotionally and award some objectively similar cases higher damages than others

System Synthesis for Networks of Programmable Blocks

The advent of sensor networks presents untapped opportunities for synthesis. We examine the problem of synthesis of behavioral specifications into networks of programmable sensor blocks. The particular behavioral specification we consider is an intuitive user-created network diagram of sensor blocks, each block having a pre-defined combinational or sequential behavior. We synthesize this specification to a new network that utilizes a minimum number of programmable blocks in place of the pre-defined blocks, thus reducing network size and hence network cost and power. We focus on the main task of this synthesis problem, namely partitioning pre-defined blocks onto a minimum number of programmable blocks, introducing the efficient but effective PareDown decomposition algorithm for the task. We describe the synthesis and simulation tools we developed. We provide results showing excellent network size reductions through such synthesis, and significant speedups of our algorithm over exhaustive search while obtaining near-optimal results for 15 real network designs as well as nearly 10,000 randomly generated designs.Comment: Submitted on behalf of EDAA (http://www.edaa.com/

A Novel Lumbar Motion Segment Classification to Predict Changes in Segmental Sagittal Alignment After Lateral Interbody Fixation.

Study designRetrospective cohort study.ObjectivesLateral interbody fixation is being increasingly used for the correction of segmental sagittal parameters. One factor that affects postoperative correction is the resistance afforded by posterior hypertrophic facet joints in the degenerative lumbar spine. In this article, we describe a novel preoperative motion segment classification system to predict postoperative correction of segmental sagittal alignment after lateral lumbar interbody fusion.MethodsPreoperative computed tomography scans were analyzed for segmental facet osseous anatomy for all patients undergoing lateral lumbar interbody fusion at 3 institutions. Each facet was assigned a facet grade (min = 0, max = 2), and the sum of the bilateral facet grades was the final motion segment grade (MSG; min = 0, max = 4). Preoperative and postoperative segmental lordosis was measured on standing lateral radiographs. Postoperative segmental lordosis was also conveyed as a percentage of the implanted graft lordosis (%GL). Simple linear regression was conducted to predict the postoperative segmental %GL according to MSG.ResultsA total of 36 patients with 59 operated levels were identified. There were 19 levels with MSG 0, 14 levels with MSG 1, 13 levels with MSG 2, 8 levels with MSG 3, and 5 levels with MSG 4. Mean %GL was 115%, 90%, 77%, 43%, and 5% for MSG 0 to 4, respectively. MSG significantly predicted postoperative %GL (P < .01). Each increase in MSG was associated with a 28% decrease in %GL.ConclusionsWe propose a novel facet-based motion segment classification system that significantly predicted postoperative segmental lordosis after lateral lumbar interbody fusion

Age-related changes to macrophages are detrimental to fracture healing in mice.

The elderly population suffers from higher rates of complications during fracture healing that result in increased morbidity and mortality. Inflammatory dysregulation is associated with increased age and is a contributing factor to the myriad of age-related diseases. Therefore, we investigated age-related changes to an important cellular regulator of inflammation, the macrophage, and the impact on fracture healing outcomes. We demonstrated that old mice (24 months) have delayed fracture healing with significantly less bone and more cartilage compared to young mice (3 months). The quantity of infiltrating macrophages into the fracture callus was similar in old and young mice. However, RNA-seq analysis demonstrated distinct differences in the transcriptomes of macrophages derived from the fracture callus of old and young mice, with an up-regulation of M1/pro-inflammatory genes in macrophages from old mice as well as dysregulation of other immune-related genes. Preventing infiltration of the fracture site by macrophages in old mice improved healing outcomes, with significantly more bone in the calluses of treated mice compared to age-matched controls. After preventing infiltration by macrophages, the macrophages remaining within the fracture callus were collected and examined via RNA-seq analysis, and their transcriptome resembled macrophages from young calluses. Taken together, infiltrating macrophages from old mice demonstrate detrimental age-related changes, and depleting infiltrating macrophages can improve fracture healing in old mice

Mean sze of the landed catch: a fishery community index for trend assessment in exploited marine ecosystems

Based on fisheries landings data I propose the size-base index (community level) Mean Size of the Landing Catch (MSL). The MSL index was estimated based on high taxonomic resolution data available from auctions (species level) and demographic data acquired during the auction, namely species landed by "size-box" categories, which is assessed mandatorily in all EU members state for fisheries quality and statistic proposes. The MSL was calculated from the average inferred size-box categories of a species weighted by their annual catch. The use of MSL allows determining inter-annual changes in the size of the catch when weighted data is available from the fishery. Using the Portuguese fisheries landing data as an example, the MSL revealed that the landing yield of large fish linearly declined over time while the catch of small fishes increased (i.e., survivors to old age was reduced by fishing). The MSL can be easily used to assess trends in marine exploited commercial communities (community rather than population level) and is fully applicable with any species-size data source (e.g., scientific surveys, visual census data). The MSL can also be applied as a key indicator within the new ecosystem-based Marine Policy Framework Strategy (ecosystem approach to fisheries), which required the use of size-based indicators for the assessment of fisheries trends in exploited marine communities.CLIMFISH project A framework for assess vulnerability of coastal fisheries to climate change in Portuguese coast - Portugal 2020 n2/SAICT/2017 - SAICTinfo:eu-repo/semantics/publishedVersio

Importance and performance analysis on the investor’s choice of an offshore mutual fund and a bank channel in Taiwan

Investors in Taiwan prefer to invest in offshore funds, and they are good customers in the eyes of the world's major fund companies. Funds are competing these investors through these 3,400 bank branches. Literature has indicated comprehensive selection criteria when investors choosing a fund, yet no study revealed the gap between what investors’ expected and experienced. The current study conducted a survey among these investors with importance-performance analysis (IPA) to fill this gap. There were two parts in the questionnaire, first part was drawn from literature to measure funds, and the second part was summarized from several depth interviews based on SERVQUAL with senior investors. 240 valid responses from current fund investors. The factors investor’s preference in evaluating a fund may be different in terms of residence areas and age. Perceived importance of fund selection criteria is not significantly different in terms of gender, education, marriage, and income levels. Test results indicated that “investment performance record”, “management fees” and “additional features” of fund, and the “sympathy” dimension of bank should be first improved by either fund or bank company respectively

Bisphosphonate's and Intermittent Parathyroid Hormone's Effect on Human Spinal Fusion: A Systematic Review of the Literature.

There has been a conscious effort to address osteoporosis in the aging population. As bisphosphonate and intermittent parathyroid hormone (PTH) therapy become more widely prescribed to treat osteoporosis, it is important to understand their effects on other physiologic processes, particularly the impact on spinal fusion. Despite early animal model studies and more recent clinical studies, the impact of these medications on spinal fusion is not fully understood. Previous animal studies suggest that bisphosphonate therapy resulted in inhibition of fusion mass with impeded maturity and an unknown effect on biomechanical strength. Prior animal studies demonstrate an improved fusion rate and fusion mass microstructure with the use of intermittent PTH. The purpose of this study was to determine if bisphosphonates and intermittent PTH treatment have impact on human spinal fusion. A systematic review of the literature published between 1980 and 2015 was conducted using major electronic databases. Studies reporting outcomes of human subjects undergoing 1, 2, or 3-level spinal fusion while receiving bisphosphonates and/or intermittent PTH treatment were included. The results of relevant human studies were analyzed for consensus on the effects of these medications in regards to spinal fusion. There were nine human studies evaluating the impact of these medications on spinal fusion. Improved fusion rates were noted in patients receiving bisphosphonates compared to control groups, and greater fusion rates in patients receiving PTH compared to control groups. Prior studies involving animal models found an improved fusion rate and fusion mass microstructure with the use of intermittent PTH. No significant complications were demonstrated in any study included in the analysis. Bisphosphonate use in humans may not be a deterrent to spinal fusion. Intermittent parathyroid use has shown early promise to increase fusion mass in both animal and human studies but further studies are needed to support routine use

Methane Migration and Its Influence on Sulfate Reduction in the Good Weather Ridge Region, South China Sea Continental Margin Sediments

Bacteria sulfate reduction is a major pathway for organic carbon oxidation in marine sediments. Upward diffusion of methane from gas hydrate deep in the sedimentary strata might be another important source of carbon for sulfate reducing bacteria and subsequently induce higher rates of sulfate reduction in sediments. Since abundant gas may migrate upward to the surface as a result of tectonic activity occurring in the accretionary wedge, this study investigates the effect of methane migration on the sulfate reduction process in continental margin sediments offshore southwestern Taiwan. Piston and gravity core samples were taken in order to evaluate vertical and spatial variations of sulfate and methane. Pore water sulfate, sulfide, methane, sediment pyrite, and organic carbon were extracted and analyzed