Investigation of sandwich material surface created by abrasive water jet (AWJ) via vibration emission

The paper presents research a of abrasive waterjet cutting of heterogeneous “sandwich“ material with different Young modulus of elasticity of the cutted surface geometry by means of vibration emission. In order to confirm hypothetical assumptions about direct relation between vibration emission and surface quality an experiment in heterogeneous material consisting of stainless steel (DIN 1.4006 / AISI 410) and alloy AlCuMg2 has been provided

Investigation of sandwich material surface created by abrasive water jet (AWJ) via vibration emission

The paper presents research a of abrasive waterjet cutting of heterogeneous “sandwich“ material with different Young modulus of elasticity of the cutted surface geometry by means of vibration emission. In order to confirm hypothetical assumptions about direct relation between vibration emission and surface quality an experiment in heterogeneous material consisting of stainless steel (DIN 1.4006 / AISI 410) and alloy AlCuMg2 has been provided

A host receptor enables type 1 pilus-mediated pathogenesis of Escherichia coli pyelonephritis

Type 1 pili have long been considered the major virulence factor enabling colonization of the urinary bladder by uropathogenic Escherichia coli (UPEC). The molecular pathogenesis of pyelonephritis is less well characterized, due to previous limitations in preclinical modeling of kidney infection. Here, we demonstrate in a recently developed mouse model that beyond bladder infection, type 1 pili also are critical for establishment of ascending pyelonephritis. Bacterial mutants lacking the type 1 pilus adhesin (FimH) were unable to establish kidney infection in male C3H/HeN mice. We developed an in vitro model of FimH-dependent UPEC binding to renal collecting duct cells, and performed a CRISPR screen in these cells, identifying desmoglein-2 as a primary renal epithelial receptor for FimH. The mannosylated extracellular domain of human DSG2 bound directly to the lectin domain of FimH in vitro, and introduction of a mutation in the FimH mannose-binding pocket abolished binding to DSG2. In infected C3H/HeN mice, type 1-piliated UPEC and Dsg2 were co-localized within collecting ducts, and administration of mannoside FIM1033, a potent small-molecule inhibitor of FimH, significantly attenuated bacterial loads in pyelonephritis. Our results broaden the biological importance of FimH, specify the first renal FimH receptor, and indicate that FimH-targeted therapeutics will also have application in pyelonephritis

Monitoring of focusing tube wear during abrasive waterjet (AWJ) cutting of AISI 309

The paper deals with the investigating the possibility of using vibrations as a potential source of information for the detection of the malfunctions during the abrasive supplying and focusing tube wear in the process of AWJ. The tested material was the stainless steel AISI 309. Variable factors in the experiment were the abrasive mass flow ma and the focusing tube diameter df. The scanned vibration signal of the material was subjected to frequency analysis. With the increase of the abrasive mass flow, the shift of the amplitudes will follow the opposite direction and decrease. Frequency spectra of all assessed signals are similar by shape in the high-frequency area

Long-range corrected DFT calculations of charge-transfer integrals in model metal-free phthalocyanine complexes

An assessment of several widely used exchange--correlation potentials in computing charge-transfer integrals is performed. In particular, we employ the recently proposed Coulomb-attenuated model which was proven by other authors to improve upon conventional functionals in the case of charge-transfer excitations. For further validation, two distinct approaches to compute the property in question are compared for a phthalocyanine dimer

Determination of technologically optimal factors of modulated waterjet

This paper deals with two methods of determination of technologically optimal factors of a hydrodynamic resonance system leading to the acquiring of maximal fundamental frequency, amplitude, pressure, and energy of oscillations of a liquid jet. These factors are determined by the differential method and the method of state space search into depth. Furthermore, theoretically predicted results are presented, interpreted, and compared with results of laboratory measurements. The benefit of the study is the optimization itself, either for the optimal input factors of the prototype or a maximum possible modification of existing equipment in order to achieve the highest possible material disintegration efficiency.Web of Science601-417917