Pigmented villonodular synovitis of the hip. A case report and review of the literature

A 73-year-old patient, whose hip was completely destroyed by pigmented villonodular synovitis, was successfully treated by a total prosthetic replacement of this articulation. The etiopathogenesis of the illness is uncertain. Its' localization in the hip is, fortunately, a rare occurrence. It can be responsible for frequently extensive articular destruction which is even more dramatic when it affects young patients, whose average age is 35. Only early diagnosis permits conservative surgical treatment: total synovectomy associated with curettage of the foyers of osteolysis and their filling with bone grafts. If the destructive lesions are too extensive, an arthrodesis or replacement arthroplasty are proposed. © 1991 Acta Medica Belgica.SCOPUS: ar.jinfo:eu-repo/semantics/publishe

Interaction between childhood maltreatment on immunogenetic risk in depression: Discovery and replication in clinical case-control samples

We thank all the participants of the studies for their generous contribution. Funding: This paper represents independent research supported by the National Institute for Health Research (NIHR) Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King’s College London. The views expressed are those of the authors and not necessarily those of the National Health Service, the NIHR, or the Department of Health. SC-W was supported by an NIHR Biomedical Research Centre Fellowship at the Institute of Psychiatry, King’s College London, U.K., and Matthew Flinders Fellowship, Flinders University, South Australia, Australia. HLF was supported by an MQ Fellows Award (MQ14F40). CML has received funding from the European Community's Seventh Framework Programme under the Marie Curie Industry-Academia Partnership and Pathways (grant 286213). The RADIANT studies were funded by a joint grant from the U.K. Medical Research Council and GlaxoSmithKline (G0701420) and by the National Institute for Health Research (NIHR) Biomedical Research Centre for Mental Health at South London and Maudsley NHS Foundation Trust and Institute of Psychiatry, Psychology and Neuroscience, King's College London. This report represents independent research part-funded by the National Institute for Health Research (NIHR) Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King’s College London. The Münster sample was funded by the German Research Foundation (DFG, grant FOR2107 DA1151/5-1 to UD; SFB-TRR58, Project C09 to UD) and the Interdisciplinary Center for Clinical Research (IZKF) of the medical faculty of Münster (grant Dan3/012/17 to UD) and MOODINFLAME FP7-HEALTH-2007-B Nr. 222963 (to VA)