FDOPA Patterns in Adrenal Glands

International audienc

Quantitative analysis of normal and pathologic adrenal glands with 18F-FDOPA PET/CT

International audienc

18F-FLT and 18F-FDG positron emission tomography for the imaging of advanced well-differentiated gastro-entero-pancreatic endocrine tumours.

International audiencePURPOSE: Gastro-entero-pancreatic (GEP) endocrine tumours are a heterogenous group of tumours of variable localization and prognosis. It has been suggested that positron emission tomography (PET) using 2-[18F]fluoro-2-deoxy-D-glucose (18F-FDG) may have a prognostic value and help to identify patients at risk of progression. [18F]fluoro-3'-deoxy-3'-L-fluorothymidine (18F-FLT) has been recently developed as a PET proliferation tracer. At present, there are no studies investigating its role in GEP. The aim of this prospective study was to assess the value of 18F-FLT-PET for the evaluation of GEP. MATERIALS AND METHODS: Ten patients with biopsy-proven locally advanced or metastasized, well-differentiated GEP neuroendocrine tumours were prospectively enrolled and scheduled for 18F-FDG and 18F-FLT-PET. Images were compared with other conventional diagnostic procedures, namely computed tomography, ultrasound, somatostatin receptor scintigraphy and with clinical and diagnostic follow-up. RESULTS: Evaluation criteria were interpreted in terms of assumed presence of tumoral tissue. According to the patient's status, FDG was positive in five out of the seven patients with stable disease and in two out of the three patients with progressive disease. No positive case was identified by 18F-FLT in either the primary or the metastatic tumour site, whatever the status of patients, and this was probably a reflection of the slow proliferation rate of tumours. CONCLUSION: These preliminary data suggest that 18F-FLT-PET is not a suitable tracer for the evaluation of advanced well-differentiated GEP tumours. FDG showed good diagnostic performance but does not help to identify patients at risk of progression

Reproducibility and volume segmentation methods on F-miso and FLT- PET-CT images in patients with lung cancer.

International audienc

The predictive value of treatment response using FDG-PET performed at day 21 of chemo-radiotherapy in patients with oesophageal Squamous cell carcinoma. A prospective, multicentre study (RTEP3).

International audienc

Impact of florbetaben PET imaging on diagnosis and management of patients with suspected Alzheimer's Disease eligible for CSF analysis in France

Annual Meeting of the Society-of-Nuclear-Medicine-and-Molecular-Imaging (SNMMI), Denver, CO, JUN 10-14, 2017International audienc

Impact of florbetaben PET imaging on diagnosis and management of patients with suspected Alzheimer's Disease eligible for CSF analysis in France

Annual Meeting of the Society-of-Nuclear-Medicine-and-Molecular-Imaging (SNMMI), Denver, CO, JUN 10-14, 2017International audienc