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E-learning adoption in higher education in Jordan: vision, reality and change
This paper discusses the implementation of an e-learning program at a Jordanian University (Al-Ahliyya Amman University). The program originally aimed to establish a virtual university which offers totally online courses but due to a number of reasons there had to be some changes in the implementation process. The paper discusses such changes and challenges faced by AAU in implementing its e-learning program from an IS project management point of view. Findings suggest that implementing such projects needs careful consideration of a variety of issues to ensure that the objectives are achieved. The case provides rich insights to other educational institutions wishing to implement such projects
Physical Activity and Obesity Indicators: National Cross Sectional Study on Lebanese Adults
Association between higher levels of physical activity and lower rates of obesity has been shown. The aim is to assess the relation between the prevalence of physical activity and the Physical Activity Index (PAI) of 300 Lebanese healthy adults, with age, gender, occupation, body mass indices and waist circumferences (WC). The cutoff points of WC for both genders were determined using the values of Body Mass Index (BMI). A cross-sectional study using self-reported valid questionnaire was conducted randomly on 150 men and 150 women, between 18 and 74 years, from Beirut region. Association between variables was performed using chi2, T-Test and ANOVA. Linear regression determined the WC cutoffs based on BMI. 22% of the population was obese with WC mean level of 92.47±14.4cm (87.71±14.4 cm for women and 97.24±12.96 cm for men). The prevalence of physical activity was 34% in overall population (27% in women and 40% in men).There was no significant association between BMI values and PAI (p< 0.085 for men and p< 0.300 for women). However there was an inverse association between WC values and PAI in both genders (p<0.043 in men and p< 0.036 in women). Linear regression showed WC cut-off point in Lebanese women with BMI ≥25 kg/m2 and ≥30 kg/m2 of 86 cm and 100 cm respectively, whereas for men it was 92.12 cm and 105 cm respectively. The prevalence of physical activity in Beirut is low with differences among genders. The highest physical activity index is associated with the decreased values of waist circumference
Contrasting Surface Behavior of Rh (111) and Pt (111) Electrodes
Low energy electron diffraction and voltammetric measurements of the Rh(lll) electrode were conducted and compared with the corresponding surface and electrochemical characteristics of Pt (111). Rhodium is unstable upon exposure to water vapor or liquid water, but retains its well-defined character after immersion to aqueous media. This is reflected in the voltammetric behavior of the clean surface, as well as the manner in which carbon monoxide and iodine are adsorbed from solution. That is, a monolayer of an oxygen-containing species, assembled into (2X2) surface structure, can either be reduced by the voltammetric treatment or replaced by adsorbing solution components without causing system disorder. The voltammetry of the Rh (111) electrode, while exhibiting the main features of several metallic single crystal surfaces, differs significantly from that of platinum electrodes normalized to the same 2D geometry. From the voltam- me\u27ric behavior, it is concluded that adsorption of high energy hydrogen is not taking place on Rh (111). Equally important, the packing density and the surface structure of the Rh(lll) — CO differs from its Pt(lll) — CO analog. While iodine chemisorption from the gas phase leads to the development of several surface structures known from the corresponding platinum work, preferential formation of the_Pt (111) (V3 X V3)R30°—I structure against the Pt(lll)(V7X V7)R19.1°—I was demonstrated. Both electronic and structural factors contribute to the contrasting surface behavior brought to focus in this work
Smoking enhances the proinflammatory effects of nucleotides on cytokine release from human lung
Nucleotides have effects on immune cells which are complex but generally proinflammatory, and have been suggested to play a role in smoking-related lung diseases. However, there have been no studies directly measuring functional responses to nucleotides in human lungs taken from smokers. We used fragments of post mortem human lung from smokers and non-smokers, incubated them with a range of nucleotides (4-1000 µM) in the presence of lipopolysaccharide (LPS; 10 µg/ml) for 24 hours and measured cytokines (IL-1β, IFNγ, IL-17, TNFα, IL-6, IL-8, IL-2 and IL-10) in the supernatants using multiplex immunoassays. Although the basal cytokine levels in the smokers were generally higher in the smokers than the non-smokers, there were no significant differences in either the basal release or the LPS-stimulated release of any of the cytokines when lungs from smokers and non-smokers were compared. There were no significant effects of ATP, ADP, AMP, UTP, α,β-methylene-ATP, P1, P4-diATP, 2-methylthio-ATP or Bz-ATP on the release of cytokines from the lungs. However, the stable ATP analogue ATPγS increased the release of IL-1β and IFNγ, and the effect was greatly increased in lungs from smokers. In non-smokers but not in smokers ATPγS increased the release of IL-17. Overall these results clearly demonstrate for the first time that in normal human lung a stable ATP analogue can enhance LPS-induced pro-inflammatory cytokine release, and that these effects are greatly altered by a prior history of smoking. This provides strong support for the suggestion that nucleotides are involved in the pathogenesis of smoking-related diseases
Factors That Hamper the Implementation of Constructability in the Gaza Strip
The subject of this research is about the barriers of constructability implementation in the Gaza strip. Therefore, this research aims at identifying the current implementation of constructability in the Gaza strip, clarifying the essential factors that hamper the implementation of constructability in the Gaza strip and clarifying solutions, whenever possible, that would help the participants to apply the constructability principles, in addition to develop guidelines for the practitioners of the construction industry. The present investigation consists of literature review in subjects related to constructability to determine the hampering factors. Interviews with experts and from the researcher experience a questionnaire was designed incorporating all possible hampering factors in theGazastrip. The questionnaire is divided into two parts: The first part is related to the importance and affect of the barrier factors in construction industry in general. This part was completed by one of the main players of a project (Contractor, Consultant, Owner or their representatives). The second part is related to the degree of existence of these barrier factors in the project under study. This part is completed by the researcher, from the project documents and through interviews with one or more of those who engaged in the project under study. This research includes 28 case studies (projects), the result of data analysis of the respondents' answers and the case studies showed the followings: All hampering factors were given a high rating by respondents in terms of the importance and affect of the barrier factors in construction industry. About 54 % of the respondents have never heard of the constructability and its concepts before. The political factors and project management factors have scored the highest rate amongst the nine main factors that hamper the implementation of constructability in theGazastrip. Nature of the project factors and knowledge & experience factors has scored the lowest rate amongst the nine main factors that hamper the implementation of constructability in theGazastrip. Recurrent closure of crossings and absence of preassembling before project's execution have scored the highest rate amongst the 56 sub-factors that hamper the implementation of constructability in the Gaza strip. Project remoteness & lack of utilities and type of contract have scored the least rate amongst the 56 sub-factors that hamper the implementation of constructability in theGazastrip. Finally, the researcher has designed a framework that acts as a guideline for the construction industry's practioners to overcome barriers of constructability, in accordance with the appearance of the barrier factors in the project life cycle, in order to achieve the desired project objectives
Effect of Age and Lordotic Angle on the Level of Lumbar Disc Herniation
It has been previously suggested in the literature that with aging, degenerative changes as well as disc herniation start at the lower lumbar segments, with higher disc involvement observed in an ascending fashion in older age groups. We conducted a study to investigate this correlation between age and level of disc herniation, and to associate it with the magnitude of the Lumbar Lordotic Angle (LLA), as measured by Cobb's method. We followed retrospectively lumbosacral spine MRI's of 1419 patients with symptomatic disc herniation. Pearson's correlation was used in order to investigate the relationship between LLA, age, and level of disc herniation. Student's t-test was applied to assess gender differences. Young patients were found to have higher LLA (R = 0.44, P < 0.0001) and lower levels of disc herniation (R = 0.302, P < 0.0001), whereas older patients had higher level herniation in lower LLA group (mean LLA 28.6° and 25.4°) and lower level herniation in high LLA group (mean LLA 33.2°). We concluded that Lumbar lordotic Cobb's angle and age can be predictors of the level of lumbar disc herniation. This did not differ among men and women (R = 0.341, P < 0.0001)
Search for proton radioactivity in <SUP>65</SUP>As, <SUP>69</SUP>Br and <SUP>77</SUP>Y
A search for proton radioactivity in 65As, 69Br and 77Y, produced as residues of fusion reactions, was carried out at the Orsay Tandem accelerator. The residues were collected at the image point of the spectrometer Soleno and implanted into the gaseous medium of an ionization chamber which was also used to detect the radioactivity protons. No such protons have been observed in the energy range of 250–600 keV and in the half-life interval of 10 μs-100 ms, within a production cross section sensitivity of 1 μb.Facultad de Ciencias Exacta
Quality by Design Approach in Liposomal Formulations: Robust Product Development
Nanomedicine is an emerging field with continuous growth and differentiation. Liposomal formulations are a major platform in nanomedicine, with more than fifteen FDA-approved liposomal products in the market. However, as is the case for other types of nanoparticle-based delivery systems, liposomal formulations and manufacturing is intrinsically complex and associated with a set of dependent and independent variables, rendering experiential optimization a tedious process in general. Quality by design (QbD) is a powerful approach that can be applied in such complex systems to facilitate product development and ensure reproducible manufacturing processes, which are an essential pre-requisite for efficient and safe therapeutics. Input variables (related to materials, processes and experiment design) and the quality attributes for the final liposomal product should follow a systematic and planned experimental design to identify critical variables and optimal formulations/processes, where these elements are subjected to risk assessment. This review discusses the current practices that employ QbD in developing liposomal-based nano-pharmaceuticals
Challenges and Opportunities in Sourcing, Preparing and Developing a Teaching Force for the UAE
Teacher education occurs along a continuum that encompasses teacher candidate recruitment, teacher candidate preparation, novice teacher induction, teacher professional development, and advanced teacher qualifications. Since the formation of the state in 1971, teacher recruitment and teacher education in the UAE have undergone several stages of development, beginning with the sourcing of teachers from the Arab world, through the establishment of in-country teacher education programs designed to produce native teachers, to the hiring of teachers from high performing school systems in the Anglophone world. Teacher education is quite a challenging enterprise, being impacted by changes in the constantly evolving education system in this young nation. High-quality teacher education candidates can be elusive, and it is difficult to attract nationals to teaching, especially males. Yet, at the same time, there are opportunities for teacher education as the country works valiantly to raise educational standards, including the development of Arabic language teacher education, the provision of continuing professional development around teacher licensure, and induction programs for novice teachers
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