Emerging Applications of Reversible Data Hiding

Reversible data hiding (RDH) is one special type of information hiding, by which the host sequence as well as the embedded data can be both restored from the marked sequence without loss. Beside media annotation and integrity authentication, recently some scholars begin to apply RDH in many other fields innovatively. In this paper, we summarize these emerging applications, including steganography, adversarial example, visual transformation, image processing, and give out the general frameworks to make these operations reversible. As far as we are concerned, this is the first paper to summarize the extended applications of RDH.Comment: ICIGP 201

Teaching Languages Online: Innovations and Challenges

Language professionals long resisted teaching online mainly because it was unthinkable to teach speaking in the online environment. Recent advances in technology, however, have made it conceivable. This chapter presents the design and implementation of online courses in Japanese and Chinese recently developed and being offered at Purdue University. We will highlight not only technologies involved, but also pedagogical innovations that helped resolve difficult issues. The efficacy of online teaching will also be touched upon. Reactions from enrolled students and the instructors that have taught the courses will also be shared

TRY plant trait database – enhanced coverage and open access

Plant traits - the morphological, anatomical, physiological, biochemical and phenological characteristics of plants - determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits and detriments to people. Plant trait data thus represent the basis for a vast area of research spanning from evolutionary biology, community and functional ecology, to biodiversity conservation, ecosystem and landscape management, restoration, biogeography and earth system modelling. Since its foundation in 2007, the TRY database of plant traits has grown continuously. It now provides unprecedented data coverage under an open access data policy and is the main plant trait database used by the research community worldwide. Increasingly, the TRY database also supports new frontiers of trait‐based plant research, including the identification of data gaps and the subsequent mobilization or measurement of new data. To support this development, in this article we evaluate the extent of the trait data compiled in TRY and analyse emerging patterns of data coverage and representativeness. Best species coverage is achieved for categorical traits - almost complete coverage for ‘plant growth form’. However, most traits relevant for ecology and vegetation modelling are characterized by continuous intraspecific variation and trait–environmental relationships. These traits have to be measured on individual plants in their respective environment. Despite unprecedented data coverage, we observe a humbling lack of completeness and representativeness of these continuous traits in many aspects. We, therefore, conclude that reducing data gaps and biases in the TRY database remains a key challenge and requires a coordinated approach to data mobilization and trait measurements. This can only be achieved in collaboration with other initiatives

Study on the Causes of Water Environmental Pollution of Important Rivers in Haihe River Basin and Countermeasures

The water quality of six important rivers in Haihe River Basin, including Yongding River, Luanhe River, North Canal, Daqing River, South Canal and Chaobai River, was evaluated. The influence of point source and non-point source on water quality was analyzed. The causes of water environmental pollution in the major rivers were preliminarily revealed. The results show that the water quality of Chaobai River is good, and the impact of point source and non-point source discharge on the water body is small. Other rivers are affected by different degrees of point source and non-point source pollution. Based on the analysis results, the engineering measures and management countermeasures for river regulation are put forward

Effect of H3BO3 on corrosion in 0.01 M NaCl solution of the interface between low alloy steel A508 and alloy 52 M

The corrosion of the low alloy steel A508-alloy 52 M interface region in buffered and non-buffered chloride containing solutions was studied by using the scanning vibrating electrode technique (SVET), scanning ion-selective electrode technique (SIET), and time of flight secondary ion mass spectroscopy (ToF-SIMS). The typical pit in low alloy steel A508 formed in NaCl solution was stopped immediately when HBO was added to the NaCl solution, and the pit became cathodic. With increasing immersion time, HBO entered into the pit, and the corrosion of A508 became general corrosion

Posttraumatic Stress Disorder and Nonadherence to Treatment in People Living With HIV: A Systematic Review and Meta-analysis

Background Posttraumatic stress disorder (PTSD) is a commonly reported and serious complication among people living with HIV (PLWH). PTSD may significantly increase unintentional non-adherence to antiretroviral therapy. In this systematic review and meta-analysis, we aimed to pool the observational studies exploring the association between PTSD and medication adherence among PLWH. Methods Comprehensive searches were conducted in PubMed/Medline, Web of Science, PsycINFO, Google Scholar, and ProQuest to identify relevant articles and dissertations. A random effects meta-analysis with inverse variance weighting was used to summarize the odds ratio (OR) across studies. Meta-regression and subgroup analyses were also carried out to assess the moderation effects for potential factors. Results By synthesizing 12 studies comprising 2489 participants, the pooled odd ratio of non-adherence to antiretroviral therapy was 1.19 (95% confidential interval (CI), 1.03-1.37,p= 0.02). No significant publication bias was detected by Egger&#39;s test (Intercept = 0.842,p= 0.284). Factors moderating the association were mean age of participants, depression adjustment, and depression (allp&lt; 0.05). Conclusions This meta-analysis supports that PTSD is related to adherence in PLWH. The hypothesized mechanisms (avoidant behavior and cognitive impairment) underlying this association need further investigation. Overall, this study highlights that clinicians should thoughtfully integrate timely mental health intervention into routine care.</p

Detection of Ricin Intoxication in Mice Using Serum Peptide Profiling by MALDI-TOF/MS

Ricin toxin has been regarded as one of the most potent poisons in the plant kingdom, and there is no effective therapeutic countermeasure or licensed vaccine against it. Consequently, early detection of ricin intoxication is necessary. In this study, we took mice as test subjects, and used the technique of Matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF/MS) and ClinProt™ microparticle beads to set up an effective detection model with an accuracy of almost 100%. Eighty-two peaks in the mass range 1000–10,000 m/z were detected by ClinProTools software, and five different peaks with m/z of 4982.49, 1333.25, 1537.86, 4285.05 and 2738.88 had the greatest contribution to the accuracy and sensitivity of this model. They may therefore provide biomarkers for ricin intoxication

TREM2 drives microglia response to amyloid-β via SYK-dependent and -independent pathways

Genetic studies have highlighted microglia as pivotal in orchestrating Alzheimer's disease (AD). Microglia that adhere to Aβ plaques acquire a transcriptional signature, "disease-associated microglia" (DAM), which largely emanates from the TREM2-DAP12 receptor complex that transmits intracellular signals through the protein tyrosine kinase SYK. The human TREM2R47H variant associated with high AD risk fails to activate microglia via SYK. We found that SYK-deficient microglia cannot encase Aβ plaques, accelerating brain pathology and behavioral deficits. SYK deficiency impaired the PI3K-AKT-GSK-3β-mTOR pathway, incapacitating anabolic support required for attaining the DAM profile. However, SYK-deficient microglia proliferated and advanced to an Apoe-expressing prodromal stage of DAM; this pathway relied on the adapter DAP10, which also binds TREM2. Thus, microglial responses to Aβ involve non-redundant SYK- and DAP10-pathways. Systemic administration of an antibody against CLEC7A, a receptor that directly activates SYK, rescued microglia activation in mice expressing the TREM2R47H allele, unveiling new options for AD immunotherapy