Iron metabolism patterns in non-anemic patients with myasthenia gravis: a cross-sectional and follow-up study

Background and purpose: Iron metabolism in myasthenia gravis (MG) and factors associated with it are explored by few published studies. Therefore, this study aimed to compare iron metabolism patterns between patients with MG and healthy individuals as well as between the same group of patients before and after immunotherapy, and to identify predictors of iron metabolism disorders in MG. Materials and methods: For this study, 105 patients and healthy individuals were included at baseline, after which paired parametric and non-parametric tests were adopted to compare their iron metabolism patterns, and multivariate binary logistic regression was used to identify predictors of iron metabolism disorders. Patients with MG were then followed up for 12 ± 3 months to explore alterations in their iron metabolism patterns after starting immunotherapy with the help of paired tests. Results: Non-anemic immunotherapy-naive patients with MG had significantly lower serum iron (SI) and transferrin saturation (TS) levels than healthy individuals. Premenopausal female was significantly associated with SI < 65 µg/dL and iron deficiency in these patients. However, iron metabolism parameters did not significantly alter after around 12 months of immunotherapy in patients with MG. Conclusion: Iron inadequacy was present in patients with MG, particularly premenopausal female patients, and it would hardly improve after immunotherapy. Given the significant role of iron in human body, it should be given more attention in patients with MG

Replacing Traditional Plastics with Biodegradable Plastics:Impact on Carbon Emissions

In recent years, a great deal of attention has been focused on the environmental impact of plastics, including the carbon emissions related to plastics, which has promoted the application of biodegradable plastics. Countries worldwide have shown high interest in replacing traditional plastics with biodegradable plastics. However, no systematic comparison has been conducted on the carbon emissions of biodegradable versus traditional plastic products. This study evaluates the carbon emissions of traditional and biodegradable plastic products (BPPs) over four stages and briefly discusses environmental and economic perspectives. Four scenarios—namely, the traditional method, chemical recycling, industrial composting, and anaerobic digestion—are considered for the disposal of waste biodegradable plastic product (WBBPs). The analysis takes China as a case study. The results show that the carbon emissions of 1000 traditional plastic products (plastic bags, lunch boxes, cups, etc.) were 52.09–150.36 carbon emissions equivalent of per kilogram (kg CO2eq), with the stage of plastic production contributing 50.71%–50.77%. In comparison, 1000 similar BPPs topped out at 21.06–56.86 kg CO2eq, approximately 13.53%–62.19% lower than traditional plastic products. The difference was mainly at the stages of plastic production and waste disposal, and the BPPs showed significant carbon reduction potential at the raw material acquisition stage. Waste disposal plays an important role in environmental impact, and composting and anaerobic digestion are considered to be preferable disposal methods for WBBPs. However, the high cost of biodegradable plastics is a challenge for their widespread use. This study has important reference significance for the sustainable development of the biodegradable plastics industry.</p

Adaptive Wall-Based Attachment Ventilation : A Comparative Study on Its Effectiveness in Airborne Infection Isolation Rooms with Negative Pressure

The transmission of coronavirus disease 2019 (COVID-19) has presented challenges for the control of the indoor environment of isolation wards. Scientific air distribution design and operation management are crucial to ensure the environmental safety of medical staff. This paper proposes the application of adaptive wall-based attachment ventilation and evaluates this air supply mode based on contaminants dispersion, removal efficiency, thermal comfort, and operating expense. Adaptive wall-based attachment ventilation provides a direct supply of fresh air to the occupied zone. In comparison with a ceiling air supply or upper sidewall air supply, adaptive wall-based attachment ventilation results in a 15%–47% lower average concentration of contaminants, for a continual release of contaminants at the same air changes per hour (ACH; 10 h−1). The contaminant removal efficiency of complete mixing ventilation cannot exceed 1. For adaptive wall-based attachment ventilation, the contaminant removal efficiency is an exponential function of the ACH. Compared with the ceiling air supply mode or upper sidewall air supply mode, adaptive wall-based attachment ventilation achieves a similar thermal comfort level (predicted mean vote (PMV) of −0.1–0.4; draught rate of 2.5%–6.7%) and a similar performance in removing contaminants, but has a lower ACH and uses less energy

Strategy for Assuring Water Security in the Haihe River Basin by 2035

Water security in the Haihe River Basin is an important component of China's ecological civilization and is vital for highquality national development of the country. Considering the development requirement for water security in the Haihe River Basin, we analyzed the problems regarding water security assurance from the perspectives of water resources, water environment, water ecology, and flood disasters. Subsequently, we predicted the development trend of water security in the Haihe River Basin by 2035 through data simulation. On this basis, an overall idea was proposed, that is, assuring water security in the Haihe River Basin by reinforcing measures for protecting water ecology, and highlighting the role of water resources carrying capacity. Focus should be placed on developing capacities regarding (1) systematic allocation and efficient utilization of water resources, (2) comprehensive improvement in water environment, (3) governance and restoration of basin ecology, and (4) prevention and emergency response of flood disasters. Furthermore, we proposed the following suggestions from a technological perspective: (1) implementing new strategies for the conservation and efficient utilization of water resources, (2) ensuring drinking water safety and improving water governance capacities, (3) establishing a water ecological pattern that features people-water harmony, and (4) developing a flood disaster prediction and response mechanism

Vortex characteristics of a gas cyclone determined with different vortex identification methods

This paper characterizes the vortex flow field in a gas cyclone based on different vortex identification methods, including vorticity method, Q criterion, λ2 criterion, Ω method and Liutex method. Analysis and comparison of isosurfaces of different vortex identification methods indicate that except vorticity method, the vortex core, the eddy flow and the short-circuit flow can be identified directly by other methods. But the small scale vortices, such as top ash ring, can only be fully recognized by Liutex method. The contours demonstrate that the magnitude of five vortex parameters is the largest in the vortex core, followed by the short-circuit flow, and the eddy flow is the smallest. But only Liutex method can predict the vortex core center and identify the most severe vortex eccentricity is in the bottom of vortex finder, the lower part of the cone and the hopper. The work not only improves the understanding of the vortex structure in a gas cyclone, which can critically affects cyclone performance, but also reveals the differences in the commonly used vortex characterization methods

Assessment of biomass demineralization on gasification : from experimental investigation, mechanism to potential application

A

Defective Nickel–Iron Layered Double Hydroxide for Enhanced Photocatalytic NO Oxidation with Significant Alleviation of NO2 Production

Photocatalysis offers a sustainable means for the oxidative removal of low concentrations of NOx (NO, NO2, N2O, N2O5, etc.) from the atmosphere. Layered double hydroxides (LDHs) are promising candidate photocatalysts owing to their unique layered and tunable chemical structures and abundant surface hydroxide (OH−) moieties, which are hydroxyl radical (·OH) precursors. However, the practical applications of LDHs are limited by their poor charge-separation ability and insufficient active sites. Herein, we developed a facile N2H4-driven etching approach to introduce dual Ni2+ and OH− vacancies (Niv and OHv, respectively) into NiFe-LDH nanosheets (hereafter referred to as NiFe-LDH-et) to facilitate improved charge-carrier separation and active Lewis acidic site (Fe3+ and Ni2+ exposed at OHv) formation. In contrast to inert pristine LDH, NiFe-LDH-et actively removed NO under visible-light illumination. Specifically, Ni76Fe24-LDH-et etched with 1.50 mmol·L−1 N2H4 solution removed 32.8% of the NO in continuously flowing air (NO feed concentration: ∼500 parts per billion (ppb)) under visible-light illumination, thereby outperforming most reported catalysts. Experimental and theoretical data revealed that the dual vacancies promoted the production of reactive oxygen species (O2·− and ·OH) and the adsorption of NO on the LDH. In situ spectroscopy demonstrated that NO was preferentially adsorbed at Lewis acidic sites, particularly exposed Fe3+ sites, converted into NO+, and subsequently oxidized to NO3− without the notable formation of the more toxic intermediate NO2, thereby alleviating risks associated with its production and emission

Replacing Traditional Plastics with Biodegradable Plastics: Impact on Carbon Emissions

In recent years, a great deal of attention has been focused on the environmental impact of plastics, including the carbon emissions related to plastics, which has promoted the application of biodegradable plastics. Countries worldwide have shown high interest in replacing traditional plastics with biodegradable plastics. However, no systematic comparison has been conducted on the carbon emissions of biodegradable versus traditional plastic products. This study evaluates the carbon emissions of traditional and biodegradable plastic products (BPPs) over four stages and briefly discusses environmental and economic perspectives. Four scenarios—namely, the traditional method, chemical recycling, industrial composting, and anaerobic digestion—are considered for the disposal of waste biodegradable plastic product (WBBPs). The analysis takes China as a case study. The results show that the carbon emissions of 1000 traditional plastic products (plastic bags, lunch boxes, cups, etc.) were 52.09–150.36 carbon emissions equivalent of per kilogram (kg CO2eq), with the stage of plastic production contributing 50.71%–50.77%. In comparison, 1000 similar BPPs topped out at 21.06–56.86 kg CO2eq, approximately 13.53%–62.19% lower than traditional plastic products. The difference was mainly at the stages of plastic production and waste disposal, and the BPPs showed significant carbon reduction potential at the raw material acquisition stage. Waste disposal plays an important role in environmental impact, and composting and anaerobic digestion are considered to be preferable disposal methods for WBBPs. However, the high cost of biodegradable plastics is a challenge for their widespread use. This study has important reference significance for the sustainable development of the biodegradable plastics industry.ISSN:2095-809