38 research outputs found

    Frequency-dependent electron power absorption mode transitions in capacitively coupled argon-oxygen plasmas

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    Phase Resolved Optical Emission Spectroscopy (PROES) measurements combined with 1d3v Particle-in-Cell/Monte Carlo Collision (PIC/MCC) simulations are performed to investigate the excitation dynamics in low-pressure capacitively coupled plasmas (CCPs) in argon-oxygen mixtures. The system used for this study is a geometrically symmetric CCP reactor operated in a fixed mixture gas composition, at fixed pressure and voltage amplitude, with a wide range of driving RF frequencies (2 ~MHz f 15 ~\le f \le~15~MHz). The measured and calculated spatio-temporal distributions of the electron impact excitation rates from the Ar ground state to the Ar 2p1~\rm{2p_1} state (with a wavelength of 750.4~nm) show good qualitative agreement. The distributions show significant frequency dependence, which is generally considered to be predictive of transitions in the dominant discharge operating mode. Three frequency ranges can be distinguished, showing distinctly different excitation characteristics: (i) in the low frequency range (f 3 f \le~3~MHz), excitation is strong at the sheaths and weak in the bulk region; (ii) at intermediate frequencies (3.5 ~MHz f 5 ~\le f \le~5~MHz), the excitation rate in the bulk region is enhanced and shows striation formation; (iii) above 6 ~MHz, excitation in the bulk gradually decreases with increasing frequency. Boltzmann term analysis was performed to quantify the frequency dependent contributions of the Ohmic and ambipolar terms to the electron power absorption.Comment: arXiv admin note: text overlap with arXiv:2205.0644

    Expiratory flow rate, breath hold and anatomic dead space influence electronic nose ability to detect lung cancer

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    BACKGROUND: Electronic noses are composites of nanosensor arrays. Numerous studies showed their potential to detect lung cancer from breath samples by analysing exhaled volatile compound pattern ("breathprint"). Expiratory flow rate, breath hold and inclusion of anatomic dead space may influence the exhaled levels of some volatile compounds; however it has not been fully addressed how these factors affect electronic nose data. Therefore, the aim of the study was to investigate these effects. METHODS: 37 healthy subjects (44 +/- 14 years) and 27 patients with lung cancer (60 +/- 10 years) participated in the study. After deep inhalation through a volatile organic compound filter, subjects exhaled at two different flow rates (50 ml/sec and 75 ml/sec) into Teflon-coated bags. The effect of breath hold was analysed after 10 seconds of deep inhalation. We also studied the effect of anatomic dead space by excluding this fraction and comparing alveolar air to mixed (alveolar + anatomic dead space) air samples. Exhaled air samples were processed with Cyranose 320 electronic nose. RESULTS: Expiratory flow rate, breath hold and the inclusion of anatomic dead space significantly altered "breathprints" in healthy individuals (p 0.05). These factors also influenced the discrimination ability of the electronic nose to detect lung cancer significantly. CONCLUSIONS: We have shown that expiratory flow, breath hold and dead space influence exhaled volatile compound pattern assessed with electronic nose. These findings suggest critical methodological recommendations to standardise sample collections for electronic nose measurements

    Abnormal Motor Activity and Thermoregulation in a Schizophrenia Rat Model for Translational Science

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    Schizophrenia is accompanied by altered motor activity and abnormal thermoregulation; therefore, the presence of these symptoms can enhance the face validity of a schizophrenia animal model. The goal was to characterize these parameters in freely moving condition of a new substrain of rats showing several schizophrenia-related alterations.Male Wistar rats were used: the new substrain housed individually (for four weeks) and treated subchronically with ketamine, and naive animals without any manipulations. Adult animals were implanted with E-Mitter transponders intraabdominally to record body temperature and locomotor activity continuously. The circadian rhythm of these parameters and the acute effects of changes in light conditions were analyzed under undisturbed circumstances, and the effects of different interventions (handling, bed changing or intraperitoneal vehicle injection) were also determined.Decreased motor activity with fragmented pattern was observed in the new substrain. However, these animals had higher body temperature during the active phase, and they showed wider range of its alterations, too. The changes in light conditions and different interventions produced blunted hyperactivity and altered body temperature responses in the new substrain. Poincaré plot analysis of body temperature revealed enhanced short- and long-term variabilities during the active phase compared to the inactive phase in both groups. Furthermore, the new substrain showed increased short- and long-term variabilities with lower degree of asymmetry suggesting autonomic dysregulation.In summary, the new substrain with schizophrenia-related phenomena showed disturbed motor activity and thermoregulation suggesting that these objectively determined parameters can be biomarkers in translational research

    Design & Implementation of Company Database for MME Subcontracting Unit

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    The purpose of this document is to introduce the software stack designed and implemented by me, during my student project. The report includes both the project description, the requirements set against the solution, the already existing alternatives for solving the problem, and the final solution that has been implemented. Reading this document you may have a better understanding of what I was working on for eleven weeks in the summer of 2016

    Regional development in Romania: institutional basis for EU cohesion policy

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    http://www.regional-studies-assoc.ac.ukinfo:eu-repo/semantics/publishe

    Motor activity parameters in undisturbed circumstances during light and dark phases.

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    <p>Mean AL (activity level; A), MI (movement index; B), RMI (relative movement index; C), PN (phase number; D), PL (phase length; E) with duration of uninterrupted immobility (DI) or active (DA) period. * p<0.05 between groups; # <0.05 between the day cycles; x p <0.05 between the DI and DA. Data are presented as means ± SEM.</p

    Body temperature parameters in undisturbed circumstances during light and dark phases.

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    <p>The mean values of BT minimum (A), BT maximum (B), BT amplitudes (C), and the mean of changes in BT between two consecutive data points (D). * p <0.05 between groups; # p <0.05 between the day cycles; x p <0.05 between the BT decreases and increases. Data are presented as means ± SEM.</p

    Schedule of the experimental protocol for selective breeding and behavioral testing.

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    <p>Abbreviations: TF: tail-flick test, PPI: prepulse inhibition test, HB: hole-board test.</p><p>Schedule of the experimental protocol for selective breeding and behavioral testing.</p
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