3,915 research outputs found
Interpretation of runaway electron synchrotron and bremsstrahlung images
The crescent spot shape observed in DIII-D runaway electron synchrotron
radiation images is shown to result from the high degree of anisotropy in the
emitted radiation, the finite spectral range of the camera and the distribution
of runaways. The finite spectral camera range is found to be particularly
important, as the radiation from the high-field side can be stronger by a
factor than the radiation from the low-field side in DIII-D. By
combining a kinetic model of the runaway dynamics with a synthetic synchrotron
diagnostic we see that physical processes not described by the kinetic model
(such as radial transport) are likely to be limiting the energy of the
runaways. We show that a population of runaways with lower dominant energies
and larger pitch-angles than those predicted by the kinetic model provide a
better match to the synchrotron measurements. Using a new synthetic
bremsstrahlung diagnostic we also simulate the view of the Gamma Ray Imager
(GRI) diagnostic used at DIII-D to resolve the spatial distribution of
runaway-generated bremsstrahlung.Comment: 21 pages, 11 figure
Influence of peptidylarginine deiminase type 4 genotype and shared epitope on clinical characteristics and autoantibody profile of rheumatoid arthritis.
Background: Recent evidence suggests that distinction
of subsets of rheumatoid arthritis (RA) depending on anticyclic
citrullinated peptide antibody (anti-CCP) status may
be helpful in distinguishing distinct aetiopathologies and in
predicting the course of disease. HLA-DRB1 shared
epitope (SE) and peptidylarginine deiminase type 4
(PADI4) genotype, both of which have been implicated in
anti-CCP generation, are assumed to be associated with
RA.
Objectives: To elucidate whether PADI4 affects the
clinical characteristics of RA, and whether it would
modulate the effect of anti-CCPs on clinical course. The
combined effect of SE and PADI4 on autoantibody profile
was also analysed.
Methods: 373 patients with RA were studied. SE,
padi4_94C.T, rheumatoid factor, anti-CCPs and antinuclear
antibodies (ANAs) were determined. Disease
severity was characterised by cumulative therapy
intensity classified into ordinal categories (CTI-1 to CTI-3)
and by Steinbrocker score.
Results: CTI was significantly associated with disease
duration, erosive disease, disease activity score (DAS) 28
and anti-CCPs. The association of anti-CCPs with CTI was
considerably influenced by padi4_94C.T genotype (C/C:
ORadj=0.93, padj=0.92; C/T: ORadj=2.92,
padj=0.093; T/T: ORadj=15.3, padj=0.002). Carriage of
padi4_94T exhibited a significant trend towards higher
Steinbrocker scores in univariate and multivariate
analyses. An association of padi4_94C.T with ANAs
was observed, with noteworthy differences depending on
SE status (SE2: ORadj=6.20, padj,0.04; SE+:
ORadj=0.36, padj=0.02) and significant heterogeneity
between the two SE strata (p=0.006).
Conclusions: PADI4 genotype in combination with anti-
CCPs and SE modulates clinical and serological characteristics
of RA
Hamiltonian dynamics of extended objects
We consider a relativistic extended object described by a reparametrization
invariant local action that depends on the extrinsic curvature of the
worldvolume swept out by the object as it evolves. We provide a Hamiltonian
formulation of the dynamics of such higher derivative models which is motivated
by the ADM formulation of general relativity. The canonical momenta are
identified by looking at boundary behavior under small deformations of the
action; the relationship between the momentum conjugate to the embedding
functions and the conserved momentum density is established. The canonical
Hamiltonian is constructed explicitly; the constraints on the phase space, both
primary and secondary, are identified and the role they play in the theory
described. The multipliers implementing the primary constraints are identified
in terms of the ADM lapse and shift variables and Hamilton's equations shown to
be consistent with the Euler-Lagrange equations.Comment: 24 pages, late
Recommended from our members
Correlated Microscale Isotope and Scanning Transmission X-Ray Analyses of Isotopically Anomalous Organic Matter from the CR2 Chondrite EET 92042
We discuss correlated examinations of organic matter from the CR2 chondrite EET 92042, using SIMS, STXM and other methods. We found a large, isotopically highly anomalous region of probable presolar origin that is C- and 13C-poor and 15N-rich
Central limit theorem for multiplicative class functions on the symmetric group
Hambly, Keevash, O'Connell and Stark have proven a central limit theorem for
the characteristic polynomial of a permutation matrix with respect to the
uniform measure on the symmetric group. We generalize this result in several
ways. We prove here a central limit theorem for multiplicative class functions
on symmetric group with respect to the Ewens measure and compute the covariance
of the real and the imaginary part in the limit. We also estimate the rate of
convergence with the Wasserstein distance.Comment: 23 pages; the mathematics is the same as in the previous version, but
there are several improvments in the presentation, including a more intuitve
name for the considered function
The Phase Diagram of an Anisotropic Potts Model
A study is made of an anisotropic Potts model in three dimensions where the
coupling depends on both the Potts state on each site but also the direction of
the bond between them using both analytical and numerical methods. The phase
diagram is mapped out for all values of the exchange interactions. Six distinct
phases are identified. Monte Carlo simulations have been used to obtain the
order parameter and the values for the energy and entropy in the ground state
and also the transition temperatures. Excellent agreement is found between the
simulated and analytic results. We find one region where there are two phase
transitions with the lines meeting in a triple point. The orbital ordering that
occurs in occurs as one of the ordered phases.Comment: 30 pages, 19 figures, one tabl
Aluminum-, Calcium- And Titanium-Rich Oxide Stardust In Ordinary Chondrite Meteorites
We report isotopic data for a total of 96 presolar oxide grains found in
residues of several unequilibrated ordinary chondrite meteorites. Identified
grain types include Al2O3, MgAl2O4, hibonite (CaAl12O19) and Ti oxide. This
work greatly increases the presolar hibonite database, and is the first report
of presolar Ti oxide. O-isotopic compositions of the grains span previously
observed ranges and indicate an origin in red giant and asymptotic giant branch
(AGB) stars of low mass (<2.5 MSun) for most grains. Cool bottom processing in
the parent AGB stars is required to explain isotopic compositions of many
grains. Potassium-41 enrichments in hibonite grains are attributable to in situ
decay of now-extinct 41Ca. Inferred initial 41Ca/40Ca ratios are in good
agreement with model predictions for low-mass AGB star envelopes, provided that
ionization suppresses 41Ca decay. Stable Mg and Ca isotopic ratios of most of
the hibonite grains reflect primarily the initial compositions of the parent
stars and are generally consistent with expectations for Galactic chemical
evolution, but require some local interstellar chemical inhomogeneity. Very
high 17O/16O or 25Mg/24Mg ratios suggest an origin for some grains in binary
star systems where mass transfer from an evolved companion has altered the
parent star compositions. A supernova origin for the hitherto enigmatic
18O-rich Group 4 grains is strongly supported by multi-element isotopic data
for two grains. The Group 4 data are consistent with an origin in a single
supernova in which variable amounts of material from the deep 16O-rich interior
mixed with a unique end-member mixture of the outer layers. The Ti oxide grains
primarily formed in low-mass AGB stars. They are smaller and rarer than
presolar Al2O3, reflecting the lower abundance of Ti than Al in AGB envelopes.Comment: Accepted for publication in ApJ; 47 pages, 13 figure
Comments on Black Holes in Matrix Theory
The recent suggestion that the entropy of Schwarzschild black holes can be
computed in matrix theory using near-extremal D-brane thermodynamics is
examined. It is found that the regime in which this approach is valid actually
describes black strings stretched across the longitudinal direction, near the
transition where black strings become unstable to the formation of black holes.
It is argued that the appropriate dynamics on the other (black hole) side of
the transition is that of the zero modes of the corresponding super Yang-Mills
theory. A suggestive mean field theory argument is given for the entropy of
black holes in all dimensions. Consequences of the analysis for matrix theory
and the holographic principle are discussed.Comment: 15 pages, harvmac, minor errors correcte
NLTE analysis of the methylidyne radical (CH) molecular lines in metal-poor stellar atmospheres
An analysis of the CH molecule in non-local thermodynamic equilibrium (NLTE)
is performed for the physical conditions of cool stellar atmospheres typical of
red giants (log g = 2.0, Teff = 4500 K) and the Sun. The aim of the present
work is to explore whether the G-band of the CH molecule, which is commonly
used in abundance diagnostics of Carbon-Enhanced Metal-Poor (CEMP) stars, is
sensitive to NLTE effects. LTE and NLTE theoretical spectra are computed with
the MULTI code. We use one-dimensional (1D) LTE hydrostatic MARCS model
atmospheres with parameters representing eleven red giant stars with
metallicities ranging from [Fe/H] = -4.0 to [Fe/H] = 0.0 and carbon-to-iron
ratios [C/Fe] = 0.0, +0.7, +1.5, and +3.0. The CH molecule model is represented
by 1981 energy levels, 18377 radiative bound-bound transitions, and 932
photo-dissociation reactions. The rates due to transitions caused by collisions
with free electrons and hydrogen atoms are computed using classical recipes.
Our calculations suggest that NLTE effects in the statistical equilibrium of
the CH molecule are significant and cannot be neglected for precision
spectroscopic analysis of C abundances. The NLTE effects in the G-band increase
with decreasing metallicity. We show that the C abundances are always
under-estimated if LTE is assumed. The NLTE corrections to C abundance inferred
from the CH feature range from +0.04 dex for the Sun to +0.21 dex for a red
giant with metallicity [Fe/H] = -4.0. Departures from the LTE assumption in the
CH molecule are non-negligible and NLTE effects have to be taken into account
in the diagnostic spectroscopy based on the CH lines. We show here that the
NLTE effects in the optical CH lines are non-negligible for the Sun and red
giant stars, but further calculations are warranted to investigate the effects
in other regimes of stellar parameters.Comment: Accepted for publication in Astronomy & Astrophysic
Majorana Electroformed Copper Mechanical Analysis
The MAJORANA DEMONSTRATOR is a large array of ultra-low background high-purity germanium detectors, enriched in 76Ge, designed to search for zero-neutrino double-beta decay. The DEMONSTRATOR will utilize ultra high purity electroformed copper for a variety of detector components and shielding. A preliminary mechanical evaluation was performed on the Majorana prototype electroformed copper material. Several samples were removed from a variety of positions on the mandrel. Tensile testing, optical metallography, scanning electron microscopy, and hardness testing were conducted to evaluate mechanical response. Analyses carried out on the Majorana prototype copper to this point show consistent mechanical response from a variety of test locations. Evaluation shows the copper meets or exceeds the design specifications
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