The Health and Health Care of People with Intellectual Disabilities

New research studies conducted by Special Olympics found disturbing evidence that individuals with intellectual disabilities face widespread health problems, while physicians, dentists and other health professionals are not receiving adequate training in order to treat them. The research reinforces previous studies that found that despite the widespread belief that individuals with intellectual disabilities receive better health care than the rest of the population, people with intellectual disabilities actually have poorer health, more specialized ealth care needs and greater difficulty accessing health care services and doctors compared to the general public.Research Methodology: Special Olympics recently commissioned two research studies related to the health and health care of individuals with intellectual disabilities

Electroblotting onto activated glass. High efficiency preparation of proteins from analytical sodium dodecyl sulfate-polyacrylamide gels for direct sequence analysis

We have developed a new method for the isolation of proteins for microsequencing. It consists of electrophoretic transfer (electroblotting) of proteins or their cleavage fragments onto activated glass filter paper sheets immediately after separation by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The proteins are immobilized on the glass fiber sheets by ionic interactions or by covalent attachment. A wide range of proteins can be prepared in this fashion with no apparent restriction due to solubility, size, charge, or other intrinsic properties of the proteins. As little as 50 ng of the transferred proteins can be detected using Coomassie Blue or fluorescent dye staining procedures and even smaller amounts of radiolabeled proteins by autoradiography. After detection, the protein- containing bands or spots are cut out and inserted directly into a gas- phase sequenator. The piece of glass fiber sheet acts as a support for the protein during the sequencing. Amounts of protein in the 5- to 150- pmol range can be sequenced, and extended runs can be obtained from the blotted samples because of improved stepwise yields and lower backgrounds. The method has been successfully applied to the sequencing of a variety of proteins and peptides isolated from one-dimensional and two-dimensional polyacrylamide gels

Application of Citizen Science Risk Communication Tools in a Vulnerable Urban Community

IMPACT. 1: The results demonstrated that eight metals occurred at statistically-significantly greater levels than natural background levels, but most were below risk-based residential soil screening levels. -- 2. This study demonstrates that community-led coalitions in collaboration with academic teams and state agencies can effectively address environmental concerns. -- 3. This data when combined with the USEPA EJ Screen tool data for 43207 suggests that the Stambaugh-Elwood community is vulnerable.OSU PARTNERS: School of Environment and Natural Resources; Division of Environmental Health Sciences; Division of Epidemiology; College of Public Health; Center for Clinical and Translational ScienceCOMMUNITY PARTNERS: Columbus Public Health; Ohio-Environmental Protection Agency; Southside Health Advisory Committee; Stambaugh-Elwood Citizens for the Environment; VERTICES, LLC; Universities Space Research Association at NASA, Marshall Space Flight CenterPRIMARY CONTACT: Darryl B. Hood ([email protected])A public participatory geographical information systems (PPGIS) demographic, environmental, socioeconomic, health status portal was developed for the Stambaugh-Elwood community in Columbus, OH. A soil study was conducted at SE residences

Development of a Public Participatory Geographic Information Systems (PPGIS) Portal to Communicate Risk from Potential Exposure to Airborne Environmental Contaminants in a Vulnerable Columbus, OH Community

IMPACT. 1: To partner with the local community organizations and stakeholders to reduce disparate health outcomes in Columbus, Ohio. -- 2. Maintain an interactive mapping website to provide community members with access to environmental health data to develop evidence-based health promotion and public/environmental health interventions. -- 3. Encourage communication and learning among academic and community partners to conduct and disseminate research findings that will result in improved health equity.OSU PARTNERS: College of Public Health; Division of Environmental Health SciencesCOMMUNITY PARTNERS: Columbus Public Health; South Side Health Advisory Committee Community; Partners; CareSource of OhioPRIMARY CONTACT: Darryl B. Hood ([email protected])The purpose of the study is to integrate PPGIS to encourage Columbus community members to utilize the findings in future risk communication of possible adverse health outcomes from environmental exposures. Soil sampling and analysis from residents and impacted communities will help to identify environmental exposures that may be related to disparate health outcomes

Energy efficient transport technology: Program summary and bibliography

The Energy Efficient Transport (EET) Program began in 1976 as an element of the NASA Aircraft Energy Efficiency (ACEE) Program. The EET Program and the results of various applications of advanced aerodynamics and active controls technology (ACT) as applicable to future subsonic transport aircraft are discussed. Advanced aerodynamics research areas included high aspect ratio supercritical wings, winglets, advanced high lift devices, natural laminar flow airfoils, hybrid laminar flow control, nacelle aerodynamic and inertial loads, propulsion/airframe integration (e.g., long duct nacelles) and wing and empennage surface coatings. In depth analytical/trade studies, numerous wind tunnel tests, and several flight tests were conducted. Improved computational methodology was also developed. The active control functions considered were maneuver load control, gust load alleviation, flutter mode control, angle of attack limiting, and pitch augmented stability. Current and advanced active control laws were synthesized and alternative control system architectures were developed and analyzed. Integrated application and fly by wire implementation of the active control functions were design requirements in one major subprogram. Additional EET research included interdisciplinary technology applications, integrated energy management, handling qualities investigations, reliability calculations, and economic evaluations related to fuel savings and cost of ownership of the selected improvements

Arkansas Cotton Variety Test 2008

The primary goal of the Arkansas Cotton Variety Test is to provide unbiased data regarding the agronomic performance of cotton varieties and advanced breeding lines in the major cotton-growing areas of Arkansas. This information helps seed companies establish marketing strategies and assists producers in choosing varieties to plant

Arkansas Cotton Variety Test 2007

The primary goal of the Arkansas Cotton Variety Test is to provide unbiased data regarding the agronomic performance of cotton varieties and advanced breeding lines in the major cotton-growing areas of Arkansas. This information helps seed companies establish marketing strategies and assists producers in choosing varieties to plant

The Mr 28,000 gap junction proteins from rat heart and liver are different but related

The sequence of the amino-terminal 32 residues of the rat heart Mr 28,000 gap junction protein presented here allows, for the first time, a sequence comparison of gap junctional proteins from different tissues (heart and liver). Comparison of the rat heart gap junction protein sequence and that available from rat liver reveals 43% sequence identity and conservative changes at an additional 25% of the positions. Both proteins exhibit a hydrophobic domain which could represent a transmembrane span of the junction. This result unequivocally demonstrates the existence of at least two forms of the gap junction protein. As yet, no homology is evident between the gap junctional proteins of either heart or liver and main intrinsic protein from rat eye lens