62 research outputs found
Error Analysis of a Rational Interpolation Spline
Abstract. This paper deals with the approximation properties of a rational cubic interpolation with linear denominator. The rational cubic spline based on function values only and the two families of parameters, in the description of the rational interpolant, modify the shape of the curve freely. Error expression of the values and the derivatives of interpolating functions are derived, which shows the interpaltion is stable
Correction: A study of association between expression of hOGG1, VDAC1, HK-2 and cervical carcinoma
A study of association between expression of hOGG1, VDAC1, HK-2 and cervical carcinoma
<p>Abstract</p> <p>Background</p> <p>Human 8-oguanine glycosylase 1(hOGG1), voltage-dependent anion channel 1(VDAC1), hexokinase 2(HK-2), represented the process of oxidative DNA damage, cell apoptosis and glycolysis, respectively. This study aims to explore the association between expression of hOGG1, VDAC1, HK-2 and cervical carcinoma.</p> <p>Methods</p> <p>A case-control study was conducted. 65 cervical biopsy samples consist of 20 control and 45 cases. The expression of hOGG1, VDAC1 and HK-2 were examined with immunohistochemistry(IHC), immunolabeling was evaluated with stereological cell counts.</p> <p>Results</p> <p>The data showed that the positive proportion of hOGG1 and HK-2 in the case group was higher than that of the control group (P < 0.05). Further, there was an increasing trend for the positive proportion and expression degree of hOGG1 and HK-2 from Control, Mild cervical carcinoma (MCC), Intermediate cervical carcinoma(ICC) to Severe cervical carcinoma(SCC) in order (P < 0.05). To VDAC1, the significant result was not obtained.</p> <p>Conclusions</p> <p>The results suggested that there was a close association between expression of hOGG1, HK-2 and cervical cancer. hOGG1 and HK-2 might play a key role at the early stage of cervical cancer, and the findings of hOGG1 and HK-2 should be considered as a significant biomarker at the early stage of cervical cancer.</p
Genomic diversity and evolution analysis of severe fever with thrombocytopenia syndrome in East Asia from 2010 to 2022
BackgroundConducting an up-to-date analysis on the genomic diversity and evolution patterns of severe fever with thrombocytopenia syndrome virus (SFTSV) is crucial for elucidating the underlying mechanisms of its emergency and pathogenicity, as well as assessing the extent of its threat to public health.MethodsComplete genome sequences of SFTSV were obtained from GenBank until December 19, 2022. A thorough phylogenetic analysis was conducted using comprehensive bioinformatics methods to estimate the genomic diversity and evolution.ResultsThe phylogenetic classification of SFTSV strains yielded seven lineages (A-G) for each genome segment. SFTSV displayed notable variations in evolutionary patterns among different regions and segments, without a linear accumulation of nucleotide substitutions within segments and regions. The comprehensive analysis revealed 54 recombination events and 17 reassortment strains, including the first discovery of recombination events involving sea-crossing and species-crossing. Selection analysis identified three positive sites (2, 671, 1353) in RNA-dependent RNA polymerase, three positive sites (22, 298, 404) in glycoprotein, and two positive sites (9, 289) in nonstructural protein. No positive selection sites were found in nucleoprotein.ConclusionOur study unveiled the existence of multiple evolutionary forces influencing SFTSV, contributing to its increasing genetic diversity, which had the potential to modify its antigenicity and pathogenicity. Furthermore, our study highlights the importance of tracking the spread of SFTSV across regions and species
Integrating Blue and Green Water to Identify Matching Characteristics of Agricultural Water and Land Resources in China
The uneven distribution and spatial mismatch between water and land resources (WLR) limit the utilization efficiency of agricultural water and land resources (AWLR), and then pose a threat to food production. There is a critical need to understand their matching characteristics for strategic resource allocation decisions and management. In this study, a holistic index (RSI) derived from resource equivalency analysis (REA) was developed which contributed to examine the abundance or deficiency of agricultural water and land resources (AWLR) based on the conception of generalized water resources (including blue water and green water). Results indicate that the matching degree of AWLR was the lowest in Northeast China, North China and Gansu in Northwest China, while the highest value was in Xinjiang due to the higher blue water use. In north China, other provinces suffered water scarcity except in Jilin, Liaoning, Henan, while all provinces in south China suffered land scarcity except in Tibet and Jiangsu. Meanwhile, the matching of AWLR was not exactly consistent with the distribution pattern of precipitation. The higher proportion of green water resources was not located in southeast China with rich precipitation; it had to do with water management. Too much or little water resources can result in the increasing of blue water use. The proposed approach can be a powerful instrument to implement public policies and management strategy as an attempt to improve the utilization efficiency and enhance the optimize-allocation of AWLR
Integrating Blue and Green Water to Identify Matching Characteristics of Agricultural Water and Land Resources in China
The uneven distribution and spatial mismatch between water and land resources (WLR) limit the utilization efficiency of agricultural water and land resources (AWLR), and then pose a threat to food production. There is a critical need to understand their matching characteristics for strategic resource allocation decisions and management. In this study, a holistic index (RSI) derived from resource equivalency analysis (REA) was developed which contributed to examine the abundance or deficiency of agricultural water and land resources (AWLR) based on the conception of generalized water resources (including blue water and green water). Results indicate that the matching degree of AWLR was the lowest in Northeast China, North China and Gansu in Northwest China, while the highest value was in Xinjiang due to the higher blue water use. In north China, other provinces suffered water scarcity except in Jilin, Liaoning, Henan, while all provinces in south China suffered land scarcity except in Tibet and Jiangsu. Meanwhile, the matching of AWLR was not exactly consistent with the distribution pattern of precipitation. The higher proportion of green water resources was not located in southeast China with rich precipitation; it had to do with water management. Too much or little water resources can result in the increasing of blue water use. The proposed approach can be a powerful instrument to implement public policies and management strategy as an attempt to improve the utilization efficiency and enhance the optimize-allocation of AWLR
Effects of phenanthrene on seed germination and some physiological activities of wheat seedling
Primary study on computer-aided qualitative and quantitative radial thin-layer chromatography methods for analysis of Yiqing tablets
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