1,340 research outputs found
Optical Monitoring of the Seyfert Galaxy NGC 4151 and Possible Periodicities in the Historical Light Curve
We report B, V, and R band CCD photometry of the Seyfert galaxy NGC 4151
obtained with the 1.0-m telescope at Weihai Observatory of Shandong University
and the 1.56-m telescope at Shanghai Astronomical Observatory from 2005
December to 2013 February. Combining all available data from literature, we
have constructed a historical light curve from 1910 to 2013 to study the
periodicity of the source using three different methods (the Jurkevich method,
the Lomb-Scargle periodogram method and the Discrete Correlation Function
method). We find possible periods of P_1=4\pm0.1, P_2=7.5\pm0.3 and
P_3=15.9\pm0.3 yr.Comment: 8 pages, 5 figures, Accepted by Research in Astronomy and
Astrophysic
Resolution of finite fuzzy relation equations based on strong pseudo-t-norms
AbstractThis work studies the problem of solving a sup-T composite finite fuzzy relation equation, where T is an infinitely distributive strong pseudo-t-norm. A criterion for the equation to have a solution is given. It is proved that if the equation is solvable then its solution set is determined by the greatest solution and a finite number of minimal solutions. A necessary and sufficient condition for the equation to have a unique solution is obtained. Also an algorithm for finding the solution set of the equation is presented
Ectopic expression of MdSPDS1 in sweet orange (Citrus sinensis Osbeck) reduces canker susceptibility: involvement of H2O2 production and transcriptional alteration
Diaquabis(1-methyl-1H-imidazole-κN 3)bis[2-(naphthalen-1-yl)acetato-κO]cobalt(II)
In the title compound, [Co(C12H9O2)2(C4H6N2)2(H2O)2], the CoII ion is located on an inversion centre and displays a distorted octahedral coordination geometry. Two O atoms from two water molecules and two carboxylate O atoms from two 2-(naphthalen-1-yl)acetate ligands are in the equatorial plane and two N atoms from two 1-methyl-1H-imidazole ligands are in the axial positions. The structure is stabilized by intramolecular O—H⋯O hydrogen bonds. Intermolecular O—H⋯O hydrogen bonds link the complex molecules into chains along [100]
Bis(1H-benzimidazole-κN 3)bis[2-(naphthalen-1-yl)acetato-κ2 O,O′]nickel(II) monohydrate
In the title compound, [Ni(C12H9O2)2(C7H6N2)2]·H2O, The NiII cation is located on a twofold rotation axis and is six-coordinated in a distorted NiN2O4 octahedral geometry. The asymmetric unit consists of a nickel(II) ion, one 2-(naphthalen-1-yl)acetate anion, a neutral benzotriazole ligand and one half of a lattice water molecule. The crystal packing is stabilized by O—H⋯O and N—H⋯O hydrogen bonds. The title compound is isotypic with its CdII analogue
Predictors for presence and abundance of small mammals in households of villages endemic for commensal rodent plague in Yunnan Province, China
<p>Abstract</p> <p>Background</p> <p>Ninety-one rodent plague epidemics have occurred in Lianghe county, Yunnan Province, China, between 1990 and 2006. This study aimed to identify predictors for the presence and abundance of small mammals in households of villages endemic for rodent plague in Lianghe county.</p> <p>Results</p> <p><it>Rattus flavipectus </it>and <it>Suncus murinus </it>were the two species captured in 110 households. Keeping cats decreased the number of captures of <it>R. flavipectus </it>by one to two thirds and the chance of reported small mammal sightings in houses by 60 to 80%. Food availability was associated with fewer captures. Keeping food in sacks decreased the small mammal captures, especially of <it>S. murinus </it>4- to 8-fold. Vegetables grown around house and maize grown in the village reduced the captures of <it>S. murinus </it>and <it>R. flavipectus </it>by 73 and 45%, respectively. An outside toilet and garbage piles near the house each reduced <it>R. flavipectus </it>captures by 39 and 37%, respectively, while raising dogs and the presence of communal latrines in the village increased <it>R. flavipectus </it>captures by 76 and 110% but were without detectable effect on small mammal sightings. Location adjacent to other houses increased captures 2-fold but reduced the chance of sightings to about half. In addition, raising ducks increased the chance of sighting small mammals 2.7-fold. Even after adjusting for these variables, households of the Dai had higher captures than those of the Han and other ethnic groups.</p> <p>Conclusion</p> <p>Both species captures were reduced by availability of species-specific foods in the environment, whereas other predictors for capture of the two species differed. Other than the beneficial effect of cats, there were also discrepancies between the effects on small mammal captures and those on sightings. These differences should be considered during the implementation and interpretation of small mammal surveys.</p
Pyrrolidin-1-ium 2-(naphthalen-1-yl)acetate–2-(naphthalen-1-yl)acetic acid (1/1)
In the title compound, C4H10N+·C12H9O2
−·C12H10O2, the pyrrolidine ring adopts an envelope conformation and the dihedral angle between the planes of the two naphthalene ring systems is 8.34 (10)°. The crystal structure is stabilized by O—H⋯O and N—H⋯O hydrogen bonds
Efficacy and safety of guselkumab for the treatment of patients with moderate-to-severe plaque psoriasis: A metaanalysis of randomized clinical trials
Purpose: To conduct a systematic analysis on data from randomized controlled trials (RCTs) on different doses of guselkumab, and provide high-quality evidence for its use in the treatment of patients with moderate-to-severe plaque psoriasis (PsO).
Methods: Related studies were searched using online search engines including MEDLINE, PubMed, and central registry of Cochrane controlled trials from January 2001 to October 2017. Only randomized, placebo-controlled, double-blind clinical trials involving guselkumab- and placebo-treated PsO subjects were included.
Results: Five eligible double-blind, randomized, and placebo-controlled trials involving patients with moderate-to-severe PsO subjects treated with guselkumab were included. Compared with the placebo groups, the proportion of patients with improvements in Psoriasis Area and Severity Index (PASI) 75 (RR= 12.14; 95% CI= 9.11-16.16; p < 0.001); PASI 90 (RR= 23.26; 95% CI =14.57-37.13; p < 0.001), and PASI 100 (RR = 37.66; 95% CI = 15.81-89.69; p < 0.001) were significantly higher than those in guselkumab-treated groups. Furthermore, the guselkumab-treated groups showed significant decreases in Physician’s Global Assessment (PGA) score (RR = 10.46; 95% CI = 7.96-13.83; p < 0.001) and the Dermatology Life Quality Index (DLQI) score (SMD = -1.3; 95% CL = -1.4 to -1.19; p < 0.001), when compared with the placebo groups. However, there were no significant differences in adverse events (AEs) (RR = 1.01; 95% CL = 0.93-1.11; p > 0.05); severe adverse events (SAEs) (RR = 1.32; 95% CI =0.69-2.54; p > 0.05) and study discontinuations (RR = 0.79; 95% CI = 0.42-1.48; p > 0.05) between the two groups.
Conclusion: This meta-analysis summarizes available evidence for the use of guselkumab in psoriasis. The results suggest that guselkumab is superior to placebo in moderate-to-severe psoriasis, and is welltolerated, effective, and safe in improving the severity of disease and quality of life.
Keywords: Guselkumab, Effectiveness, Safety, Plaque psoriasis, Meta-analysis, Quality of lif
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