10,457 research outputs found
Solid-state NMR investigations of cellulose structure and interactions with matrix polysaccharides in plant primary cell walls
Until recently, the 3D architecture of plant cell walls was poorly understood due to the lack of high-resolution techniques for characterizing the molecular structure, dynamics, and intermolecular interactions of the wall polysaccharides in these insoluble biomolecular mixtures. We introduced multidimensional solid-state NMR (SSNMR) spectroscopy, coupled with [superscript 13]C labelling of whole plants, to determine the spatial arrangements of macromolecules in near-native plant cell walls. Here we review key evidence from 2D and 3D correlation NMR spectra that show relatively few cellulose–hemicellulose cross peaks but many cellulose–pectin cross peaks, indicating that cellulose microfibrils are not extensively coated by hemicellulose and all three major polysaccharides exist in a single network rather than two separate networks as previously proposed. The number of glucan chains in the primary-wall cellulose microfibrils has been under active debate recently. We show detailed analysis of quantitative [superscript 13]C SSNMR spectra of cellulose in various wild-type (WT) and mutant Arabidopsis and Brachypodium primary cell walls, which consistently indicate that primary-wall cellulose microfibrils contain at least 24 glucan chains.United States. Dept. of Energy. Office of Basic Energy Sciences (Center for Lignocellulose Structure and Formation Award # DE-SC0001090
Strong Cosmic Censorship in Charged de Sitter spacetime with Scalar Field Non-minimally Coupled to Curvature
We examine the stability and the strong cosmic censorship in the
Reissner-Nordstrom-de Sitter (RN-dS) black hole by investigating the evolution
of a scalar field non-minimally coupled to the curvature. We find that when the
coupling parameter is negative, the RN-dS black hole experiences instability.
The instability disappears when the coupling parameter becomes non-negative.
With the increase of the coupling parameter, the violation of the strong cosmic
censorship occurs at a larger critical charge ratio. But such an increase of
the critical charge is suppressed by the increase of the cosmological constant.
Different from the minimal coupling situation, it is possible to accommodate
in the near extremal black hole when the scalar field is
non-minimally coupled to curvature. The increase of the cosmological constant
can allow to be satisfied for even smaller value of the coupling
parameter. The existence of implies that the resulting curvature
can continuously cross the Cauchy horizon.Comment: 14 pages, 4 figures, 5 table
Analyzing Bivariate Survival Data with Interval Sampling and Application to Cancer Epidemiology
In medical follow-up studies, ordered bivariate survival data are frequently encountered when bivariate failure events are used as the outcomes to identify the progression of a disease. In cancer studies interest could be focused on bivariate failure times, for example, time from birth to cancer onset and time from cancer onset to death. This paper considers a sampling scheme where the first failure event (cancer onset) is identified within a calendar time interval, the time of the initiating event (birth) can be retrospectively confirmed, and the occurrence of the second event (death) is observed sub ject to right censoring. To analyze this type of bivariate failure time data, it is important to recognize the presence of bias arising due to interval sampling. In this paper, nonparametric and semiparametric methods are developed to analyze the bivariate survival data with interval sampling under stationary and semi-stationary conditions. Numerical studies demonstrate the proposed estimating approaches perform well with practical sample sizes in different simulated models. We apply the proposed methods to SEER ovarian cancer registry data for illustration of the methods and theory
Rotor fault diagnosis based on wavelet packet energy spectrum and adaptive fuzzy weighted support vector machine
In this study, a novel application of a wavelet packet energy-weighted support vector machine (WPE-WSVM) is proposed to perform fault classification of helicopter rotor. Because the helicopter rotor fault signal is weak, it is difficult to extract fault feature. The wavelet package is adopted to decompose the vibration signals on the fuselage into different frequency bands, and to eliminate the noise. And then single signal was reconstructed to extract the energy in each frequency band serving as fault feature vectors. And support vector machine was applied for classifying the failure mode of the helicopter rotor. For classification task support vector machine is used due to its good robustness and generalization performances. But the classification accuracy of standard support vector machine is relative slow when the number of samples of different classes is dramatically different. So a fuzzy weighted support vector machine was proposed, which added weight coefficient to samples of different classes. A comparative analysis of standard support vector machine and proposed fuzzy weighted support vector machine is done. The proposed fuzzy weighted support vector machine improved the classification accuracy of class with fewer samples. The proposed method is sufficiently accurate, fast, and robust, which makes it suitable for use in helicopter rotor fault diagnosis applications
Research on dynamic characteristics of spiral basilar membrane after replacing artificial auditory ossicle based on the reconstructed human ear model
In this paper, PATRAN software was used to establish a complete 3D finite element model of human ears, and it was then combined with NASTRAN software to analyze frequency responses. This paper conducted a detailed analysis on the dynamic parameters including umbo and stapes displacements of normal human ears under sound pressures 90 dB and 105 dB. The numerically computational results were compared with experimental data. When the analyzed frequency was less than 1000 Hz, the computational result of numerical simulation was well consistent with the upper limit. When the analyzed frequency was more than 1000 Hz, the computational result of numerical simulation was well consistent with the lower limit. Therefore, the numerically computational model was reliable. In addition, based on the verified model, this paper studied vibration characteristics of spiral basilar membrane after replacing artificial auditory ossicle based on the whole hearing system, and found that vibration characteristics of spiral basilar membrane had an obvious change at low and high frequencies after replacing artificial auditory ossicle TORP. Using finite element method to analyze vibration characteristics of spiral basilar membrane can well predict the hearing recovery effect after replacing artificial auditory ossicle. Compared with normal ears, the vibration level of spiral basilar membrane after replacing artificial auditory ossicle has slowed down in 100 Hz-600 Hz, 2000 Hz-4000 Hz and 7000 Hz-10000 Hz, and has been strengthened in 600 Hz-2000 Hz and 4000 Hz-7000 Hz, which provided some help for the hearing recovery at the high-frequency band
Optimal View Angle in Collective Dynamics of Self-propelled Agents
We study a system of self-propelled agents in which each agent has a part of
omnidirectional or panoramic view of its sensor disc, the field of vision of
the agent in this case is only a sector of a disc bounded by two radii and the
included arc. The inclination of these two radii is characterized as the view
angle. Contrary to our intuition, we find that, the non-omnidirectional-view
for swarm agents with periodic boundary conditions in noiseless Vicsek model
can accelerate the transient process of the emergence of the ordered state. One
consequent implication is that, there are generally superfluous communications
in the Vicsek Model, which may even obstruct the possible fast swarm emergence.
This phenomenon may invoke further efforts and attentions to explore the
underlying mechanism of the emergence in self-propelled agents.Comment: 4 pages, 6 figure
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