Comparison of MIL-101(Cr) metal-organic framework and 13X zeolite monoliths for CO2 capture

A comparative study was conducted to determine the pore properties and adsorptive performance of monoliths containing either the MIL-101(Cr) metal-organic framework or 13X zeolite for carbon dioxide (CO2) capture. Although there has been a great deal of previous work on CO2 adsorption onto zeolites and MOFs, there has been far fewer studies on structured adsorbents such as monoliths. The results indicate that MIL-101(Cr) monoliths have 1.3 times higher porosity than 13X zeolite monoliths. Increasing CO2 partial pressure in the gas mixture shortens breakthrough and equilibrium times and increases their breakthrough and equilibrium adsorption capacities of CO2. MIL-101(Cr) monoliths show better mass transfer of CO2 in the adsorbent bed with shorter breakthrough and equilibrium times of about 20% and 35%, respectively, than 13X zeolite monoliths. The adsorption capacity of CO2 on MIL-101(Cr) monoliths is higher by about 37% (based on weight in mmol/g) at breakthrough and slightly lower by about 7% at equilibrium when compared to 13X zeolite monoliths. MIL-101(Cr) monoliths were found to be 1.5 times more efficient for CO2 adsorption than 13X zeolite monoliths. The effects of regeneration temperature after CO2 adsorption on MIL-101(Cr) and 13X zeolite monoliths were studied and results showed an increase in CO2 adsorption capacity as the regeneration temperature was increased. In summary, the study showed MIL-101(Cr) monoliths have better CO2 adsorption properties than 13X zeolite monoliths

tert-Butyl 3-[N-(tert-butoxy­carbonyl)methyl­amino]-4-methoxy­imino-3-methyl­piperidine-1-carboxyl­ate

The title compound, C18H33N3O5, was prepared from N-tert-butoxy­carbonyl-4-piperidone using a nine-step reaction, including condensation, methyl­ation, oximation, hydrolysis, esterification, ammonolysis, Hoffmann degradation, tert-butoxy­carbonyl protection and methyl­ation. The E configuration of the methyl­oxime geometry of the compound is confirmed

Low major histocompatibility complex class II DQA diversity in the Giant Panda (Ailuropoda melanoleuca)

© 2007 Zhu et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licens

THE HERBAL MIXTURE XIAO-CHAI-HU TANG (XCHT) INDUCES APOPTOSIS OF HUMAN HEPATOCELLULAR CARCINOMA HUH7 CELLS IN VITRO AND IN VIVO

Background: Xiao-Chai-Hu Tang (XCHT) is an extract of seven herbs with anticancer properties, but its mechanism of action is unknown. In this study, we evaluated XCHT-treated hepatocellular carcinoma (HCC) for anti-proliferative and pro-apoptotic effects. Materials and Methods: Using a hepatic cancer xenograft model, we investigated the in vivo efficacy of XCHT against tumor growth by evaluating tumor volume and weight, as well as measuring apoptosis and cellular proliferation within the tumor. To study the effects of XCHT in vitro, we measured the cell viability of XCHT-treated Huh7 cells, as well as colony formation and apoptosis. To identify a potential mechanism of action, the gene and protein expression levels of Bax, Bcl-2, CDK4 and cyclin-D1 were measured in XCHT-treated Huh7 cells. Results: We found that XCHT reduced tumor size and weight, as well as significantly decreased cell viability both in vivo and in vitro. XCHT suppressed the expression of the proliferation marker Ki-67 in HCC tissues and inhibited Huh7 colony formation. XCHT induced apoptosis in HCC tumor tissues and in Huh7 cells. Finally, XCHT altered the expression of Bax, Bcl-2, CDK4 and cyclin-D1, which halted cell proliferation and promoted apoptosis. Conclusion: Our data suggest that XCHT enhances expression of pro-apoptotic pathways, resulting in potent anticancer activity