Systematic review of brucellosis in the Middle East: disease frequency in ruminants and humans and risk factors for human infection

This paper considers the problem of finding global states incoming to a specified global state in a Boolean network, which may be useful for pre-processing of finding a sequence of control actions for a Boolean network and for identifying the basin of attraction for a given attractor, We show that this problem is NP-hard in general along with related theoretical results, On the other hand, we present algorithms that are much faster than the naive exhaustive search-based algorithm. ©2007 IEEE.link_to_subscribed_fulltex

A laser-driven target of high-density nuclear polarized hydrogen gas

We report the best figure-of-merit achieved for an internal nuclear polarized hydrogen gas target and a Monte Carlo simulation of spin-exchange optical pumping. The dimensions of the apparatus were optimized using the simulation and the experimental results were in good agreement with the simulation. The best result achieved for this target was 50.5% polarization with 58.2% degree of dissociation of the sample beam exiting the storage cell at a hydrogen flow rate of $1.1\times 10^{18}$ atoms/s.Comment: Accepted as a Rapid Communication article in Phys. Rev.

Evidence for Proportionate Partition Between the Magnetic Field and Hot Gas in Turbulent Cassiopeia A

We present a deep X-ray observation of the young Galactic supernova remnant Cas A, acquired with the ROSAT High Resolution Imager. This high dynamic range (232 ks) image reveals low-surface-brightness X-ray structure, which appears qualitatively similar to corresponding radio features. We consider the correlation between the X-ray and radio morphologies and its physical implications. After correcting for the inhomogeneous absorption across the remnant, we performed a point by point (4" resolution) surface brightness comparison between the X-ray and radio images. We find a strong (r = 0.75) log-log correlation, implying an overall relationship of $\log(\Sigma_{_{\rm X-ray}}) \propto (2.21\pm0.05) \times \log(\Sigma_{_{\rm radio}})$. This is consistent with proportionate partition (and possibly equipartition) between the local magnetic field and the hot gas --- implying that Cas A's plasma is fully turbulent and continuously amplifying the magnetic field.Comment: 8 pages with embedded bitmapped figures, Accepted by ApJ Letters 5/1/9

A Geometrical Method of Decoupling

The computation of tunes and matched beam distributions are essential steps in the analysis of circular accelerators. If certain symmetries - like midplane symmetrie - are present, then it is possible to treat the betatron motion in the horizontal, the vertical plane and (under certain circumstances) the longitudinal motion separately using the well-known Courant-Snyder theory, or to apply transformations that have been described previously as for instance the method of Teng and Edwards. In a preceeding paper it has been shown that this method requires a modification for the treatment of isochronous cyclotrons with non-negligible space charge forces. Unfortunately the modification was numerically not as stable as desired and it was still unclear, if the extension would work for all thinkable cases. Hence a systematic derivation of a more general treatment seemed advisable. In a second paper the author suggested the use of real Dirac matrices as basic tools to coupled linear optics and gave a straightforward recipe to decouple positive definite Hamiltonians with imaginary eigenvalues. In this article this method is generalized and simplified in order to formulate a straightforward method to decouple Hamiltonian matrices with eigenvalues on the real and the imaginary axis. It is shown that this algebraic decoupling is closely related to a geometric "decoupling" by the orthogonalization of the vectors $\vec E$, $\vec B$ and $\vec P$, that were introduced with the so-called "electromechanical equivalence". We present a structure-preserving block-diagonalization of symplectic or Hamiltonian matrices, respectively. When used iteratively, the decoupling algorithm can also be applied to n-dimensional systems and requires ${\cal O}(n^2)$ iterations to converge to a given precision.Comment: 13 pages, 1 figur

Who will use pre-exposure prophylaxis (PrEP) and why?: Understanding PrEP awareness and acceptability amongst men who have sex with men in the UK – a mixed methods study

Background: Recent clinical trials suggest that pre-exposure prophylaxis (PrEP) may reduce HIV transmission by up to 86% for men who have sex with men (MSM), whilst relatively high levels of PrEP acceptability have been reported to date. This study examines PrEP awareness amongst sub-groups of MSM communities and acceptability amongst MSM in a low prevalence region (Scotland, UK), using a mixed methods design. Methods: Quantitative surveys of n = 690 MSM recruited online via social and sociosexual media were analysed using descriptive statistics and multivariate logistic regression. In addition, n = 10 in-depth qualitative interviews with MSM were analysed thematically. Results: Under one third (29.7%) of MSM had heard of PrEP, with awareness related to living in large cities, degree level education, commercial gay scene use and reporting an HIV test in the last year. Just under half of participants (47.8%) were likely to use PrEP if it were available but there was no relationship between PrEP acceptability and previous PrEP awareness. Younger men (18–25 years) and those who report higher risk UAI were significantly more likely to say they would use PrEP. Qualitative data described specific PrEP scenarios, illustrating how risk, patterns of sexual practice and social relationships could affect motivation for and nature of PrEP use. Conclusion: These findings suggest substantial interest PrEP amongst MSM reporting HIV risk behaviours in Scotland. Given the Proud results, there is a strong case to investigate PrEP implementation within the UK. However, it appears that disparities in awareness have already emerged along traditional indicators of inequality. Our research identifies the need for comprehensive support when PrEP is introduced, including a key online component, to ensure equity of awareness across diverse MSM communities (e.g. by geography, education, gay scene use and HIV proximity), as well as to responding to the diverse informational and sexual health needs of all MSM communities

Fast outflows in compact radio sources: evidence for AGN-induced feedback in the early stages of radio source evolution

We present intermediate resolution, wide wavelength coverage spectra for a complete sample of 14 compact radio sources taken with the aim of investigating the impact of the nuclear activity on the circumnuclear (ISM) in the early stages of radio source evolution. We observe spatially extended line emission (up to 20 kpc) in the majority of sources which is consistent with a quiescent halo. In the nuclear apertures we observe broad, highly complex emission line profiles. Multiple Gaussian modelling of the [O III]5007 line reveals 2-4 components which can have FWHM and blueshifts relative to the halo of up to 2000 km/s. We interpret these broad, blueshifted components as material in outflow and discuss the kinematical evidence for jet-driven outflows. Comparisons with samples in the literature show that compact radio sources harbour more extreme nuclear kinematics than their extended counterparts, a trend seen within our sample with larger velocities in the smaller sources. The observed velocities are also likely to be influenced by source orientation with respect to the observer's line of sight. Nine sources have associated HI absorption. In common with the optical emission line gas, the HI profiles are often highly complex with the majority of the detected components significantly blueshifted, tracing outflows in the neutral gas. The sample has been tested for stratification in the ISM (FWHM/ionisation potential/critical density) as suggested by Holt et al. (2003) for PKS1345+12 but we find no significant trends within the sample using a Spearman Rank analysis. This study supports the idea that compact radio sources are young radio loud AGN observed during the early stages of their evolution and currently shedding their natal cocoons through extreme circumnuclear outflows.Comment: Accepted for publication in MNRAS, 24 pages, 7 figure

PKS2250-41: a case study for triggering

We present the results of a multiwavelength study of the z = 0.31 radio source PKS2250-41. Integral field unit and long-slit spectroscopy obtained using VIMOS and FORS1 on the VLT, and archival HST optical imaging observations are used to study the morphology, kinematics and ionisation state of the extended emission line region (EELR) surrounding this source, and also a companion galaxy at a similar redshift. Near-infrared imaging observations obtained using the NTT are used to analyse the underlying galaxy morphologies. The EELR displays a complex variety of different gas kinematics and ionization states, consistent with a mixture of radio source shocks and AGN photoionization. The radio galaxy is likely to lie within a group environment, and is plausibly undergoing interactions with one or more other objects. The disk-like galaxy to the northeast of the radio source lies at a similar redshift to the radio galaxy itself, and has its major axis position angle aligned with the filamentary continuum and line emission extending outwards from the radio galaxy. This filamentary structure is most plausibly interpreted as a tidal structure associated with an interaction involving the radio source host galaxy and the aligned companion galaxy to the north-east; this encounter may have potentially triggered the current epoch of radio source activity. Overall, PKS2250-41 displays some of the best evidence that radio source activity can be triggered in this manner. [abridged]Comment: 16 pages, 13 figures (some colour). Accepted for publication in MNRAS. Abstract abridge

HEAO 1 observations of the X-ray pulsar 4U1626-67

Results of an observation of the 7-s pulsar 4U1626-67 with the A2 experiments on HEAO 1 are reported. The phase-averaged X-ray spectra which change radically as a function of pulse phase. Included in this spectral change is the sudden appearance and subsequent decay of a continuum or emission feature with a mean energy of 19 keV which contains about 1/2 the power in this spectral range. Pulse timing results include a new determination of the pulse period and a factor 8 reduction in the upper limit for the light travel time for orbital periods between 1 and 7 hours. The findings for this system are discussed and compared with the general nature of pulsar spectra

Mission Design for the Lunar Pallet Lander

Marshall Space Flight Center is developing a small lunar lander capable of delivering up to 300 kg of payload to the lunar surface near the North or South Pole. Originally designed as a lander for a small rover, the Lunar Pallet Lander, has seen several design iterations over the last couple of years. This paper will cover how the vehicle and mission design changed from being a co-manifested payload candidate in NASAs Space Launch System to its current design, which could be launched with an Evolved Expendable Launch Vehicle (EELV), and reach a wide range of polar landing sites