The Effect of Physical Activity on the Insulin Response to Frequent Meals

Long, uninterrupted bouts of sedentary behavior are thought to negatively influence insulin sensitivity, and may impact metabolic function regardless of adherence to general physical activity guidelines. The purpose of this study was to determine the combined effect of physical activity (1 h continuous exercise v. intermittent exercise throughout the day) and meal consumption on glucose excursions, insulin secretion, and appetite markers in obese individuals with prediabetes. Methods: Eleven healthy, obese subjects (\u3e30 kg/m2) with prediabetes underwent 3, 12 h study days including sedentary behavior (SED), exercise (EX; 1h morning exercise, 60-65% VO2 max), and physical activity (PA; 12 hourly, intensity-matched 5-minute bouts). Meals were provided every 2 h. Blood samples were taken every 10 min for 12 h. Baseline and area under the curve (AUC) for serum glucose, insulin, c-peptide, total PYY concentrations, and subjective appetite ratings; as well as insulin pulsatility were determined. Results: No significant differences in baseline glucose, insulin or c-peptide concentrations across study days were observed (P\u3e0.05). Glucose AUC (12 h and 2 h) were significantly different across study days, with AUC attenuated in the PA condition compared to the EX condition (P\u3c0.05). The 12 h incremental insulin AUC was reduced by PA compared to SED (173,985±3556.8 v. 227,352±4581.2 pmol/L*min for 12 h, respectively; P\u3c0.05). Similarly, a significant main effect of condition in the 2 h insulin AUC was found, with the PA condition being reduced compared to SED condition (P\u3c0.05), but no differences between the EX and SED conditions. A significant reduction in 2 h c-peptide AUC was demonstrated with EX and PA compared to the SED condition (P\u3c0.05). Deconvolution analysis of insulin secretion revealed no significant differences between experimental conditions. There were no significant differences in total PYY between experimental conditions, though subjective measures of hunger and satiety were reduced with continuous and intermittent exercise. Conclusions: Short bouts of physical activity throughout the day attenuate glucose excursions and improve insulin clearance compared to an exercise day with 1 h of morning exercise. Further, both continuous and intermittent exercise mechanisms that improve satiety in obese individuals are not related to changes in concentrations of PYY

Cardiovascular and metabolic demands of the kettlebell swing using a Tabata interval versus a traditional resistance protocol

International Journal of Exercise Science 7(3) : 179-185, 2014. Tabata (TAB) training, consisting of eight cycles of 20 seconds of maximal exercise followed by 10 seconds of rest, is time-efficient, with aerobic and anaerobic benefit. This study investigated the cardiovascular and metabolic demands of a TAB versus traditional (TRAD) resistance protocol with the kettlebell swing. Fourteen young (18-25y), non-obese (BMI 25.7±0.8 kg/m2) participants reported on three occasions. All testing incorporated measurements of HR, oxygen consumption, and blood lactate accumulation. Each participant completed Tabata kettlebell swings (male- 8kg, female- 4.5kg; 8 intervals; 20s maximal repetitions, 10s rest). On a subsequent visit (TRAD), the total swings from the TAB protocol were evenly divided into 4 sets, with 90s rest between sets. Outcome measures were compared using paired t-tests. The TAB was completed more quickly than the TRAD protocol (240.0±0.0 v. 521.5±3.3 sec, P\u3c0.01), at a higher perceived exertion (Borg RPE; 15.1±0.7 v. 11.7±0.9, P\u3c0.01). The TAB elicited a higher average VO2 value (33.1±1.5 v. 27.2±1.6 ml/kg/min, P\u3c0.01), percent of VO2peak achieved (71.0±0.3 v. 58.4±0.3%, P\u3c0.01), maximal HR (162.4±4.6 v. 145.6±4.8 bpm, P\u3c0.01), and post-exercise blood lactate concentration (6.4±1.1 v. 3.7±0.5 mmol/L, P\u3c0.01). Conclusion: The kettlebell swing demonstrated significantly greater cardiovascular and metabolic responses within a TAB vs. TRAD framework. Appropriate screening and risk stratification are advised before implementing kettlebell swings

The Impact of the Cold Pressor Test on Inter-Arm Differences in Blood Pressure

International Journal of Exercise Science 16(2): 875-884, 2023. A large inter-arm difference (IAD+; ≥10mmHg between arms at rest) in blood pressure (BP) at rest is linked to cardiovascular risk, and exercise can change this difference. As mechanisms for IAD are elusive, unique physiological stimuli may provide insight towards a better understanding of this phenomenon. The cold pressor test (CPT) has a potent effect on BP and acts primarily through sympathetic nervous system (SNS) stimulation, though the effects of SNS stimulation on IAD are unknown. Therefore, the purpose of the present study was to examine the effects of the CPT on IAD. BP was monitored simultaneously using two automated, auscultatory monitors (SunTech Tango) and a non-invasive hemodynamic device (Physioflow). Participants completed a CPT test, including a 15-minute rest, three pre-test BP measurements (averaged), and a three-minute water immersion (3°C; measurements at 30-sec and 2-min). Descriptive statistics were calculated, and a repeated measures ANOVA test used to compare both the absolute and relative IAD responses. The CPT induced an average absolute increase in IAD of 4.0 mmHg at 30-sec and 6.7mmHg at 2-min across all participants (P\u3c0.05). Differences in both the absolute and relative IAD responses to the CPT were noted between IAD- and IAD+ individuals (P\u3c0.05). Despite a consistent HR response to the CPT between groups, stroke volume was lower in IAD+ participants at 30-sec and 2-min. Sympathetic stimulation via the CPT induced changes in both the inter-arm difference in blood pressure and hemodynamics in young, apparently-healthy individuals

Do Overweight and Obese Individuals Select a “Moderate Intensity” Workload When Asked to Do So?

The purpose of this study was (1) to determine if overweight/obese individuals (age 26–50 y) would self-select moderate exercise intensity when asked to do so and (2) to determine how this self-selected workload compared to exercising at a workload (60% peak aerobic capacity) that is known to provide cardioprotective health benefits. Oxygen consumption (VO2) and energy expenditure were measured in 33 men/women (BMI ≥ 27 kg/m2) who completed two 30 min walking bouts: (1) self-selected walking pace on an indoor track and (2) prescribed exercise pace (60% VO2 peak) on a treadmill. The data revealed that (1) the prescribed intensity was 6% higher than the self-selected pace and elicited a higher energy expenditure (P < 0.05) than the self-selected pace (+83 kJ); (2) overweight subjects walked at a slightly lower percentage of VO2 peak than the obese subjects (P < 0.05); (3) men walked at a lower percentage of VO2 peak than the women (P < 0.05). In conclusion when asked to walk at a moderate intensity, overweight/obese individuals tended to select a lower workload in the “moderate intensity” range which could be maintained for 30 min; however, a higher intensity which would be more cardioprotective could not be maintained for 30 min by most individuals

Stability of Resistance Training Implement alters EMG Activity during the Overhead Press

International Journal of Exercise Science 11(1): 708-716, 2018. Kettlebells often replace dumbbells during common resistance training exercises such as the overhead press. When performing an overhead press, the center of mass of a dumbbell is in line with the glenohumeral joint. In comparison, the center of mass of the kettlebell is posterior to the glenohumeral joint. Posterior displacement of the kettlebell center of mass may result in less stability during the pressing motion. The purpose of this study was to examine muscle activity during an overhead press with resistance training implements of differing stability. Surface electromyography (EMG) for the anterior deltoid and pectoralis major was analyzed for 21 subjects. Technique and pace of the overhead press were standardized and monitored. Filtered EMG data were collected, normalized, and average peak amplitude as a percentage of MVIC was calculated for each repetition. A repeated-measures analysis of variance was used to compare EMG values for the anterior deltoid and pectoralis major across implements. A statistically significant increase in normalized EMG activity (p \u3c .05) was identified in the anterior deltoid when using the dumbbell (63.3±13.3%) compared to the kettlebell (57.9±15.0%). In this study, EMG activity was augmented in the anterior deltoid when using the more stable implement, the dumbbell

A Comparison of Muscle Recruitment Across Three Straight-Legged, Hinge-Pattern Resistance Training Exercises

International Journal of Exercise Science 16(4): 12-22, 2023. Hinge exercises are critical to building a balanced resistance training program in concert with ‘knee-dominant’ (e.g., squat, lunge) exercises. Biomechanical differences between various straight-legged hinge (SLH) exercises may alter muscle activation. For example, a Romanian deadlift (RDL) is a closed-chain SLH, while a reverse hyperextension (RH) is open-chain. Likewise, the RDL offers resistance via gravity while the cable pull-through (CP) offers redirected-resistance through a pulley. A deeper understanding of the potential impact of these biomechanical differences between these exercises may improve their application to specific goals. Participants completed repetition-maximum (RM) testing on the RDL, RH, and CP. On a follow-up visit, surface electromyography of the longissimus, multifidus, gluteus maximus, semitendinosus, and biceps femoris, muscles that contribute to lumbar/hip extension, was recorded. After a warm-up, participants completed maximal voluntary isometric contractions (MVICs) in each muscle. They then completed five repetitions of the RDL, RH, and CP at 50% of estimated one RM. Testing order was randomized. A one-way, repeated-measures ANOVA test was used in each muscle to compare activation (%MVIC) across the three exercises. Shifting from a gravity- (RDL) to a redirected-resistance (CP) SLH significantly decreased activation in the longissimus (-11.0%), multifidus (-14.1%), biceps femoris (-13.1%), and semitendinosus (-6.8%). Alternately, changing from a closed- (RDL) to an open-chain (RH) SLH significantly increased activation in the gluteus maximus (+19.5%), biceps femoris (+27.9%), and semitendinosus (+18.2). Alterations in the execution of a SLH can change muscle activation in lumbar/hip extensors

The Quantification of Muscle Activation During the Loaded Carry Movement Pattern

International Journal of Exercise Science 17(1): 480-490, 2024. The ‘loaded carry’ is a popular resistance training activity that activates core musculature across multiple movement planes while the body is in locomotion. ‘Hold’ exercises are similar to carry exercises but lack the locomotive aspect. Both carry and hold exercises can be completed bilaterally (farmer’s carry (FC) and hold (FH)) or unilaterally (suitcase carry (SC) and hold (SH)). A deeper understanding of muscle activation between the FC and SC and intensity-matched FH and SH might improve their application. Healthy, college-aged individuals were recruited and surface electromyography of the rectus abdominis (RA), external oblique (EO), longissimus (LT), and multifidus (MF) was measured bilaterally using standard procedures. Participants completed time- and intensity-matched randomized sets of the plank, FC, SC, FH, and SH separated by 5-minute rests. A one-way ANOVA was utilized to compare exercises. The FC/FH load averaged 50.7±1.9 kg, where it was used across equally weighted dumbbells. The FC elicited higher activation bilaterally in the LT, MF, RA, and EO, compared to the FH. The SC/SH single-dumbbell load averaged 25.3±0.95 kg. There was greater activation bilaterally in the LT and MF during the SC compared to the SH. However, on the ipsilateral side of the SC, the RA and EO displayed greater activation compared to the SH, but this was not different on the contralateral side. The FC and SC were characterized by increased core muscle activation bilaterally, with the SC exhibiting unique additions to ipsilateral muscle activation

Eight Weeks of Kettlebell Swing Training Does Not Improve Sprint Performance in Recreationally Active Females

International Journal of Exercise Science 9(4): 437-444, 2016. The kettlebell swing (KBS), emphasizing cyclical, explosive hip extension in the horizontal plane, aligns with movement- and velocity-specificity of sprinting. The present study examined the effect of an eight-week KBS intervention on sprinting in recreationally-active females, in comparison to an eight-week intervention using the stiff-legged deadlift (SDL). Following a pre-testing session measuring 30 meter sprint and countermovement vertical jump performance, participants were divided evenly by sprint time into KBS (n=8) and SDL (n=10) cohorts. Following familiarization with the exercises, KBS met twice weekly to perform swings using the Tabata interval (20s work, 10s rest, 8 rounds), stressing a rapid, explosive tempo. In contrast, the SDL group performed their Tabata stiff-legged deadlifts at a conventional resistance training tempo (2 seconds concentric, 2 seconds eccentric). Following eight weeks and greater than 95% training adherence, the SDL group only had a slightly greater average training volume (~3%) than KBS. No significant differences in pre-test values, or changes were noted in sprint performance from pre- to post-intervention in either group. An improvement in vertical jump performance was noted across groups. Potential explanations for the lack of sprint improvement compared to previous studies include differences between recreationally-active and athletic females, and low exercise volume (~46% of a comparable study with improvements in vertical jump). Future studies should seek to determine the appropriate volume and intensity for KBS components of sprint programming

Environmental cues and constraints affecting the seasonality of dominant calanoid copepods in brackish, coastal waters: a case study of Acartia, Temora and Eurytemora species in the south-west Baltic

Information on physiological rates and tolerances helps one gain a cause-and-effect understanding of the role that some environmental (bottom–up) factors play in regulating the seasonality and productivity of key species. We combined the results of laboratory experiments on reproductive success and field time series data on adult abundance to explore factors controlling the seasonality of Acartia spp., Eurytemora affinis and Temora longicornis, key copepods of brackish, coastal and temperate environments. Patterns in laboratory and field data were discussed using a metabolic framework that included the effects of ‘controlling’, ‘masking’ and ‘directive’ environmental factors. Over a 5-year period, changes in adult abundance within two south-west Baltic field sites (Kiel Fjord Pier, 54°19′89N, 10°09′06E, 12–21 psu, and North/Baltic Sea Canal NOK, 54°20′45N, 9°57′02E, 4–10 psu) were evaluated with respect to changes in temperature, salinity, day length and chlorophyll a concentration. Acartia spp. dominated the copepod assemblage at both sites (up to 16,764 and 21,771 females m−3 at NOK and Pier) and was 4 to 10 times more abundant than E. affinis (to 2,939 m−3 at NOK) and T. longicornis (to 1,959 m−3 at Pier), respectively. Species-specific salinity tolerance explains differences in adult abundance between sampling sites whereas phenological differences among species are best explained by the influence of species-specific thermal windows and prey requirements supporting survival and egg production. Multiple intrinsic and extrinsic (environmental) factors influence the production of different egg types (normal and resting), regulate life-history strategies and influence match–mismatch dynamics

Periodontal health and gingival diseases and conditions on an intact and a reduced periodontium::Consensus report of workgroup 1 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions

Periodontal health is defined by absence of clinically detectable inflammation. There is a biological level of immune surveillance that is consistent with clinical gingival health and homeostasis. Clinical gingival health may be found in a periodontium that is intact, i.e. without clinical attachment loss or bone loss, and on a reduced periodontium in either a non-periodontitis patient (e.g. in patients with some form of gingival recession or following crown lengthening surgery) or in a patient with a history of periodontitis who is currently periodontally stable. Clinical gingival health can be restored following treatment of gingivitis and periodontitis. However, the treated and stable periodontitis patient with current gingival health remains at increased risk of recurrent periodontitis, and accordingly, must be closely monitored. Two broad categories of gingival diseases include non-dental plaque biofilm-induced gingival diseases and dental plaque-induced gingivitis. Non-dental plaque biofilm-induced gingival diseases include a variety of conditions that are not caused by plaque and usually do not resolve following plaque removal. Such lesions may be manifestations of a systemic condition or may be localized to the oral cavity. Dental plaque-induced gingivitis has a variety of clinical signs and symptoms, and both local predisposing factors and systemic modifying factors can affect its extent, severity, and progression. Dental plaque-induced gingivitis may arise on an intact periodontium or on a reduced periodontium in either a non-periodontitis patient or in a currently stable "periodontitis patient" i.e. successfully treated, in whom clinical inflammation has been eliminated (or substantially reduced). A periodontitis patient with gingival inflammation remains a periodontitis patient (Figure 1), and comprehensive risk assessment and management are imperative to ensure early prevention and/or treatment of recurrent/progressive periodontitis. Precision dental medicine defines a patient-centered approach to care, and therefore, creates differences in the way in which a "case" of gingival health or gingivitis is defined for clinical practice as opposed to epidemiologically in population prevalence surveys. Thus, case definitions of gingival health and gingivitis are presented for both purposes. While gingival health and gingivitis have many clinical features, case definitions are primarily predicated on presence or absence of bleeding on probing. Here we classify gingival health and gingival diseases/conditions, along with a summary table of diagnostic features for defining health and gingivitis in various clinical situations