Living at the Friendship House: Findings from the Transition Planning Inventory

A residential initiative, named the Friendship House, was created through advocates focused on helping people with intellectual disabilities live independently in affordable and safe housing on a university campus. The Friendship House is a small residence hall where individuals with intellectual disabilities live side-by-side with similarly aged and same gendered university students. Qualitative finding as in resident reports and observational data provides support that the Friendship House experience has been successful. However, to better equip these residents with intellectual disabilities, it is important to assess the program in terms of post school transition acquisition skills. This study focuses on whether the residents with intellectual disabilities are mastering the skills necessary to live successful lives after high school. Hence, the purpose of this quantitative study is to determine the effect of living in the Friendship House on the acquired transition skills (as measured by the nine Transition Planning Inventory skill sets) on individuals with intellectual disabilities

Living at the Friendship House: Findings from the Transition Planning Inventory

A residential initiative, named the Friendship House, was created through advocates focused on helping people with intellectual disabilities live independently in affordable and safe housing on a university campus. The Friendship House is a small residence hall where individuals with intellectual disabilities live side-by-side with similarly aged and same gendered university students. Qualitative finding as in resident reports and observational data provides support that the Friendship House experience has been successful. However, to better equip these residents with intellectual disabilities, it is important to assess the program in terms of post school transition acquisition skills. This study focuses on whether the residents with intellectual disabilities are mastering the skills necessary to live successful lives after high school. Hence, the purpose of this quantitative study is to determine the effect of living in the Friendship House on the acquired transition skills (as measured by the nine Transition Planning Inventory skill sets) on individuals with intellectual disabilities

Center for STEM Inquiry: STEM Scholars Program

This project engages science or math education majors in education research projects via coursework and intensive field placements. A May term STEM methods course includes pedagogical and curriculum instruction. The Hope STEM scholars then implement inquiry-based, action research as co-leaders of two STEM Academies - summer inquiry experiences for high school students

Conquering Worrisome Word Problems – Algebra Success

High school students can struggle with word problems in upper level math classes. Causes for this struggle could include lower reading comprehension, limited mathematic vocabulary, and difficulty changing words to algebraic expressions. This article proposes three techniques to help teachers instruct these struggling students that include (a) organization by difficulty of comprehension and computation (b) scaffolding and (c) utilizing the Explain, Practice and Assess (EPA) strategy

Foundations to Algebraic Mastery

Realizing that Algebra 1 is a gatekeeper to not only higher mathematics, but STEM careers in general (Blanchard & Muller, 2015; Stoelinga & Lynn, 2013), it is imperative that our students master the content matter. To this end, four essential components to ensuring success for Algebra 1 students have been identified: (a) basic skill development, (b) computational ease, (c) step-by-step scaffolding, and (d) the extensive use of the Explain-Practice-Assess (EPA) Strategy (Holmes, Spence, Finn, & Ingram, 2017). In this article, each of these four components is described in detail with accompanying examples. These examples model evidenced-based practices and provide a very useful guide for algebra teachers in their own classrooms

Factors that Influence the Sociological Construct of Adulthood in Adults with Moderate Intellectual Disabilities (ID): An ID Case Study

The most common criteria used to evaluate successful transition into adulthood for young adults have included obtaining employment and establishing autonomous non-relative social support networks (correlate to community involvement). Hence, employment and community involvement are critical in the transition to adulthood for all young adults, including those with intellectual disabilities (ID). However, with respect to those with ID, the construct of Adulthood is multi-faceted and murky. Hence, this exploratory study seeks to determine factors (measured by the Transition Planning Inventory-2) that impact the sociological construct of Adulthood in young adults with ID and to model pictorially the relationship between them. Results indicate for adults with ID, vocational purpose, community involvement, and wellness explain 47% of the variance in the sociological construct of Adulthood. Factor analysis reveals that vocational purpose is characterized by employment and self determination; community involvement by leisure activity, community participation, and interpersonal relationships; and wellness by health and daily living

The Effects of Project-Based Learning (PBL) Approach on the Achievement and Efficacy of High School Mathematics Students: A Longitudinal Study Investigating the Effects of the PBL Approach in Mathematics Education

Abstract Project-Based Learning (PBL) is a teaching method that is significantly different from the conventional classroom teaching; however, the positive effects of PBL have not been clearly established. This longitudinal study investigates the effect of Project-Based Learning on secondary mathematics' students in order to determine both academic skill development and motivational factors that affect learning. Motivational factors to be measured include self-regulation, self-efficacy, and learning strategies. Unlike previous studies conducted in conventional school environments, this study is conducted on a dedicated project-based high school, where PBL is not being used as additional or supplemental teaching, but as a whole curriculum. This study provides the opportunity for teachers to reflect on the effectiveness of this pedagogical approach to mathematics teaching and learning. Because this study's participants represent a wide range of mathematical abilities and demographic diversity, it may bring clarity on controversial issues regarding the benefits of PBL on certain populations. Specifically, PBL has been shown to work well with students who already have a deep conceptual knowledge of the subject matter, but it may be less effective with those possessing only surface knowledge (Vernon & Blake, 1993; Dochy, Segers, van den bossche, & Gijbels, 2003). In addition, the benefits of PBL on low SES students are debated Keywords: PBL, mathematics, education This study follows 8th and 9th graders through high school graduation, thus providing teachers with a solid picture of the developmental process of learning secondary mathematics through PBL

Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity.

Global dispersal and increasing frequency of the SARS-CoV-2 spike protein variant D614G are suggestive of a selective advantage but may also be due to a random founder effect. We investigate the hypothesis for positive selection of spike D614G in the United Kingdom using more than 25,000 whole genome SARS-CoV-2 sequences. Despite the availability of a large dataset, well represented by both spike 614 variants, not all approaches showed a conclusive signal of positive selection. Population genetic analysis indicates that 614G increases in frequency relative to 614D in a manner consistent with a selective advantage. We do not find any indication that patients infected with the spike 614G variant have higher COVID-19 mortality or clinical severity, but 614G is associated with higher viral load and younger age of patients. Significant differences in growth and size of 614G phylogenetic clusters indicate a need for continued study of this variant

Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans

Genome-wide association studies (GWAS) have identified numerous common prostate cancer (PrCa) susceptibility loci. We have fine-mapped 64 GWAS regions known at the conclusion of the iCOGS study using large-scale genotyping and imputation in 25 723 PrCa cases and 26 274 controls of European ancestry. We detected evidence for multiple independent signals at 16 regions, 12 of which contained additional newly identified significant associations. A single signal comprising a spectrum of correlated variation was observed at 39 regions; 35 of which are now described by a novel more significantly associated lead SNP, while the originally reported variant remained as the lead SNP only in 4 regions. We also confirmed two association signals in Europeans that had been previously reported only in East-Asian GWAS. Based on statistical evidence and linkage disequilibrium (LD) structure, we have curated and narrowed down the list of the most likely candidate causal variants for each region. Functional annotation using data from ENCODE filtered for PrCa cell lines and eQTL analysis demonstrated significant enrichment for overlap with bio-features within this set. By incorporating the novel risk variants identified here alongside the refined data for existing association signals, we estimate that these loci now explain ∼38.9% of the familial relative risk of PrCa, an 8.9% improvement over the previously reported GWAS tag SNPs. This suggests that a significant fraction of the heritability of PrCa may have been hidden during the discovery phase of GWAS, in particular due to the presence of multiple independent signals within the same regio

Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B.1.617.2) compared with alpha (B.1.1.7) variants of concern: a cohort study

Background: The SARS-CoV-2 delta (B.1.617.2) variant was first detected in England in March, 2021. It has since rapidly become the predominant lineage, owing to high transmissibility. It is suspected that the delta variant is associated with more severe disease than the previously dominant alpha (B.1.1.7) variant. We aimed to characterise the severity of the delta variant compared with the alpha variant by determining the relative risk of hospital attendance outcomes. Methods: This cohort study was done among all patients with COVID-19 in England between March 29 and May 23, 2021, who were identified as being infected with either the alpha or delta SARS-CoV-2 variant through whole-genome sequencing. Individual-level data on these patients were linked to routine health-care datasets on vaccination, emergency care attendance, hospital admission, and mortality (data from Public Health England's Second Generation Surveillance System and COVID-19-associated deaths dataset; the National Immunisation Management System; and NHS Digital Secondary Uses Services and Emergency Care Data Set). The risk for hospital admission and emergency care attendance were compared between patients with sequencing-confirmed delta and alpha variants for the whole cohort and by vaccination status subgroups. Stratified Cox regression was used to adjust for age, sex, ethnicity, deprivation, recent international travel, area of residence, calendar week, and vaccination status. Findings: Individual-level data on 43 338 COVID-19-positive patients (8682 with the delta variant, 34 656 with the alpha variant; median age 31 years [IQR 17–43]) were included in our analysis. 196 (2·3%) patients with the delta variant versus 764 (2·2%) patients with the alpha variant were admitted to hospital within 14 days after the specimen was taken (adjusted hazard ratio [HR] 2·26 [95% CI 1·32–3·89]). 498 (5·7%) patients with the delta variant versus 1448 (4·2%) patients with the alpha variant were admitted to hospital or attended emergency care within 14 days (adjusted HR 1·45 [1·08–1·95]). Most patients were unvaccinated (32 078 [74·0%] across both groups). The HRs for vaccinated patients with the delta variant versus the alpha variant (adjusted HR for hospital admission 1·94 [95% CI 0·47–8·05] and for hospital admission or emergency care attendance 1·58 [0·69–3·61]) were similar to the HRs for unvaccinated patients (2·32 [1·29–4·16] and 1·43 [1·04–1·97]; p=0·82 for both) but the precision for the vaccinated subgroup was low. Interpretation: This large national study found a higher hospital admission or emergency care attendance risk for patients with COVID-19 infected with the delta variant compared with the alpha variant. Results suggest that outbreaks of the delta variant in unvaccinated populations might lead to a greater burden on health-care services than the alpha variant. Funding: Medical Research Council; UK Research and Innovation; Department of Health and Social Care; and National Institute for Health Research