Investigating Grip Range of Motion and Force Exerted by Individuals with and without Hand Arthritis during Functional Tasks and while Swinging a Golf Club

Hand arthritis is the leading cause of disability in individuals over the age of 50; resulting in dysfunction and pain, making activities of daily living and recreational activities such as golf difficult. Few studies have been conducted on the biomechanical response of individuals with hand arthritis when performing functional activities. This research quantified hand grip movements and strength differences seen in individuals with hand arthritis. Using a video-based motion capture system (Dartfish), a grip limitation of 17.2% (maximum flexion), and 12.7% (maximum extension) was discovered. A wireless finger force measurement system (FingerTPS), was used to show that larger diameter, softer firmness golf grips assisted in reducing the grip force in individuals with and without hand arthritis during a golf swing. This research will benefit the sport biomechanics and clinical fields, providing quantitative results to develop more sophisticated joint protection devices and gain a better understanding of hand arthritis mechanics

How to deliver an effective senior exercise class

In a time when people are living longer and more active lifestyles, we propose that we may be selling many of our seniors short by oversimplifying the design of group exercise classes. This article suggests ways of delivering effective senior exercise classes incorporating functional movement and sound conditioning principles applied to the older adult population.Funding for the interventions that this article was based on was provided in part by Carolina Meadows CCRC, Chapel Hill, NC, US

Look at Me Now: What Attracts U.S. Shareholders?

This paper investigates the underlying determinants of home bias using a comprehensive data set on U.S. investors' aggregate holdings of every foreign stock. Among those foreign stocks that are not listed on U.S. exchanges, which account for more than 96 percent of our usable data sample, we find that U.S. investors prefer firms with characteristics associated with greater information transparency, such as stronger home-country accounting standards. We document that a U.S. cross-listing is economically important, as U.S. ownership of a foreign firm roughly doubles upon cross-listing in the United States. We explore the cross-sectional variation in this "cross-listing effect" and find that the increase in U.S. investment is greatest for firms that are from weak accounting backgrounds and are otherwise informationally opaque, suggesting that the key effect of cross-listing is improvements in disclosure that are valued by U.S. investors. By contrast, cross-listing does not increase the appeal of stocks from countries with weak shareholder rights, suggesting that U.S. cross-listing cannot substitute for legal protections in the home country. Nor does the cross-listing effect appear to be driven simply by increased "familiarity"� with the stock or lowered cross-border transactions costs.

U.S. International Equity Investment

U.S. investors are the largest group of international equity investors in the world, but to date conclusive evidence on which types of foreign firms are able to attract U.S. investment is not available. Using a comprehensive dataset of all U.S. investment in foreign equities, we find that the single most important determinant of the amount of U.S. investment a foreign firm receives is whether the firm cross-lists on a U.S. exchange. Correcting for selection biases, cross-listing leads to a doubling (or more) in U.S. investment, an impact greater than all other factors combined. We also show that our firm-level analysis has implications for country-level studies, suggesting that research investigating equity investment patterns at the country-level should include cross-listing as an endogenous control variable. We describe easy-to-implement methods for including the importance of cross-listing at the country level.

Mitochondrial ferredoxin determines vulnerability of cells to copper excess

The essential micronutrient copper is tightly regulated in organisms, as environmental exposure or homeostasis defects can cause toxicity and neurodegenerative disease. The principal target(s) of copper toxicity have not been pinpointed, but one key effect is impaired supply of iron-sulphur (FeS) clusters to the essential protein Rli1 (ABCE1). Here, to find upstream FeS-biosynthesis/delivery protein(s) responsible for this, we compared copper sensitivity of yeast overexpressing candidate targets. Overexpression of the mitochondrial ferredoxin Yah1 produced copper hyper-resistance. 55Fe turnover assays revealed that FeS1-integrity of Yah1 was particularly vulnerable to copper among the test proteins. Furthermore, destabilization of the FeS domain of Yah1 produced copper hypersensitivity, and YAH1 overexpression rescued Rli1 dysfunction. This copper-resistance function was conserved in the human ferredoxin, Fdx2. The data indicate that the essential mitochondrial ferredoxin is an important copper target, determining a tipping point where plentiful copper supply becomes excess. This knowledge could help in tackling copper-related diseases

Graduate Keynote. Golf Grip Force Evaluation in Individuals with and without Hand Arthritis Using a New Wearable Sensor Technology

BACKGROUND Hand osteoarthritis (H-OA) is the most common type of osteoarthritis largely affecting individuals over 45. H-OA involves pain, loss of grip strength and limiting participation in recreational activities such as golf. Currently, a number of ‘arthritic’ grips are designed using joint protection principles to ‘reduce hand forces and tight gripping’. However, no comprehensive examinations in their effectiveness have been conducted. HYPOTHESIS The purpose of this study is to systematically analyse the hand forces produced from various golf grips and arthritis grips at the distal-phalanges of the hand-grip interface in individuals with and without hand arthritis using new wearable sensor technology. METHODS The finger forces in the hand were measured using Pressure Profiles FingerTPS system for participant’s bottom gripping hand thumb, index, middle and ring fingers. The participants performed 3 golf shots using a real ball on artificial turf with 12, mid-iron clubs fitted with various types of standard and arthritis grips. RESULTS Preliminary results of 4 healthy participants demonstrated that serrated style golf grips designed for players with arthritis produced some of the highest forces. Also, players with larger hand length measures produce higher forces in smaller diameter grips and small hand length measures in larger diameter grips. DISCUSSION These preliminary results demonstrate the possibility that ‘arthritic’ golf grips are not appropriately designed for the given user along with the potential relationship between grip geometry and hand size to finger forces. In better understanding the mechanics of arthritis and its relation to sports, the design of more advanced sporting equipment can be developed

The process of individual unlearning: a neglected topic in an under-researched field

This article presents the findings of a participative action research project into how arts-based inquiry can revitalise equality and diversity organisational practices. We demonstrate that the arts-based methodologies introduced enabled participants to explore the meanings they brought to equality and diversity work, by creating a liminal space for learning. We illustrate our findings through an exploration of how participants engaged with the inquiry, the learning about equality and diversity that took place in the workshops and the challenges and opportunities of translating this into change practice in the workplace. The article’s originality lies in its analysis of poetic writings, dreams and visual artefacts created in the context of participative inquiry. Engaging with tacit knowledge extended understanding of the contribution that arts-based, aesthetic inquiry can bring to organisational practice, and more specifically towards restoring the transformative potential of organisational practices to promote equality and diversity

Can I Trust You? Negative Affective Priming Influences Social Judgments in Schizophrenia

Successful social interactions rely on the ability to make accurate judgments based on social cues as well as the ability to control the influence of internal or external affective information on those judgments. Prior research suggests that individuals with schizophrenia misinterpret social stimuli and this misinterpretation contributes to impaired social functioning. We tested the hypothesis that for people with schizophrenia, social judgments are abnormally influenced by affective information. Twenty-three patients with schizophrenia and 35 healthy control participants rated the trustworthiness of faces following the presentation of neutral, negative (threat-related), or positive affective primes. Results showed that all participants rated faces following negative affective primes as less trustworthy than faces following neutral or positive primes. Importantly, this effect was significantly more pronounced for participants with schizophrenia, suggesting that schizophrenia may be characterized by an exaggerated influence of negative affective information on social judgment. Furthermore, the extent that the negative affective prime influenced trustworthiness judgments was significantly associated with patients' severity of positive symptoms, particularly feelings of persecution. These findings suggest that for people with schizophrenia, negative affective information contributes to an interpretive bias, consistent with paranoid ideation, when judging the trustworthiness of others. This bias may contribute to social impairments in schizophrenia.Psycholog

Why Do Firms Use Insurance to Fund Worker Health Benefits? The Role of Corporate Finance

When a firm offers health benefits to workers, it exposes the firm to the risk of making payments when workers get sick. A firm can either pay health expenses out of its general assets, keeping the risk inside the firm, or it can purchase insurance, shifting the risk outside the firm. We analyze the firm’s decision to manage this risk. Using data on the insurance decisions of publicly-traded firms, we find that smaller firms, firms with more investment opportunities, and firms that face a convex tax schedule are more likely to hedge the risk of health benefit payments. Health risk is common to all firms, making this application an important contribution to understanding firms’ hedging decisions. Additionally, we reveal new and important determinants of the hedging decision relative to regulatory regimes. We also show that hedging health risk mitigates investment-cash flow sensitivities