1,037 research outputs found

    Evaluation of the fidelity of feature descriptor-based specimen tracking for automatic NDE data integration

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    This research addresses inspection location tracking in the field of nondestructive evaluation (NDE) using a computer vision technique to determine the position and orientation of typical NDE equipment in a test setup. The objective is the tracking accuracy for typical NDE equipment to facilitate automatic NDE data integration. Since the employed tracking technique relies on surface curvatures of an object of interest, the accuracy can be only experimentally determined. We work with flash-thermography and conducted an experiment in which we tracked a specimen and a thermography flash hood, measured the spatial relation between both, and used the relation as input to map thermography data onto a 3D model of the specimen. The results indicate an appropriate accuracy, however, unveiled calibration challenges

    Aerodynamic Characterization of a Modern Launch Vehicle

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    A modern launch vehicle is by necessity an extremely integrated design. The accurate characterization of its aerodynamic characteristics is essential to determine design loads, to design flight control laws, and to establish performance. The NASA Ares Aerodynamics Panel has been responsible for technical planning, execution, and vetting of the aerodynamic characterization of the Ares I vehicle. An aerodynamics team supporting the Panel consists of wind tunnel engineers, computational engineers, database engineers, and other analysts that address topics such as uncertainty quantification. The team resides at three NASA centers: Langley Research Center, Marshall Space Flight Center, and Ames Research Center. The Panel has developed strategies to synergistically combine both the wind tunnel efforts and the computational efforts with the goal of validating the computations. Selected examples highlight key flow physics and, where possible, the fidelity of the comparisons between wind tunnel results and the computations. Lessons learned summarize what has been gleaned during the project and can be useful for other vehicle development projects

    Redox changes accompanying inorganic carbon limitation in Synechocystis sp. PCC 6803

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    AbstractInorganic carbon (Ci) is the major sink for photosynthetic reductant in organisms capable of oxygenic photosynthesis. In the absence of abundant Ci, the cyanobacterium Synechocystis sp. strain PCC6803 expresses a high affinity Ci acquisition system, the CO2-concentrating mechanisms (CCM), controlled by the transcriptional regulator CcmR and the metabolites NADP+ and α-ketoglutarate, which act as co-repressors of CcmR by modulating its DNA binding. The CCM thus responds to internal cellular redox changes during the transition from Ci-replete to Ci-limited conditions. However, the actual changes in the metabolic state of the NADPH/NADP+ system that occur during the transition to Ci-limited conditions remain ill-defined. Analysis of changes in the redox state of cells experiencing Ci limitation reveals systematic changes associated with physiological adjustments and a trend towards the quinone and NADP pools becoming highly reduced. A rapid and persistent increase in F0 was observed in cells reaching the Ci-limited state, as was the induction of photoprotective fluorescence quenching. Systematic changes in the fluorescence induction transients were also observed. As with Chl fluorescence, a transient reduction of the NADPH pool (‘M’ peak), is assigned to State 2→State 1 transition associated with increased electron flow to NADP+. This was followed by a characteristic decline, which was abolished by Ci limitation or inhibition of the Calvin–Benson–Bassham (CBB) cycle and is thus assigned to the activation of the CBB cycle. The results are consistent with the proposed regulation of the CCM and provide new information on the nature of the Chl and NADPH fluorescence induction curves

    Automated Construction and Insertion of Layer-by Layer Finite Element Sub-Models of Damaged Composites

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    Finite element models of composite structures are generally shell-based and modeled at the laminate level. More detailed layer-by-layer lamina-level models are sometimes needed for representing joints or for modeling defect growth processes. We describe a method and toolkit for automating the creation and insertion of layerby-layer finite element sub-models of composite laminate. We focus in particular on representing damage captured from nondestructive evaluation (NDE) measurements. The method is based on scripting existing simulation and solid modeling tools (ABAQUS and ACIS). It works even on complicated, curved CAD models. The submodel location is identified by the intersection of a cylinder with the structure. We then execute a series of instructions to generate a new shell with the submodel region removed, generate the layer-by-layer submodel, and bond together the layers and models with desired boundary conditions and defects. The instructions represent the steps of lamination and bonding for creating the composite. The output of the method includes CAD models of the new shell and each lamina within the submodel, and a Python script for ABAQUS that will load the CAD models, bond them together, and apply the specified boundary conditions

    Effect of urinary pH and diatrizoate on Bence Jones protein nephrotoxicity in the rat

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    Effect of urinary pH and diatrizoate on Bence Jones protein nephrotoxicity in the rat. Both low urinary pH and radiocontrast agents may intensify myeloma nephrotoxicity. To study the effects of these factors, we determined inulin clearances (CIn) before and after infusions of human Bence Jones protein (BJP) in male Sprague-Dawley rats in a dose previously shown to be nephrotoxic. Rats that drank 0.15 M NaHCO3 for 48 hr before study had no change in CIn (+ 3 ± 20%) after BJP unlike those that drank 0.15 M NH4Cl (- 33 ± 14%, P < 0.05); urinary pH differed (7.6 ± 0.1 vs. 6.2 ± 0.1, P < 0.05), but urinary flow rates did not. The acidifying regimen was used in all subsequent groups. Infusion of diatrizoate (DTZ) after BJP produced a further decrease in CIn (- 85 ± 8%, P < 0.05). In contrast, infusion of albumin, which raised plasma protein concentration to that seen in BJP-infused rats, did not change CIn (+ 39 ± 17%). Infusion of beta-lactoglobulin also led to a greater decrease in CIn after DTZ (- 35 ± 9 vs. - 67 ± 8%, P < 0.05), but myoglobin did not (- 58 ± 7 vs. - 54 ± 12%). Urinary pH and flow rate did not differ between any DTZ-infused group and its appropriate control. These data suggest that aciduria independent of urinary flow rate increases the nephrotoxicity of BJP. In this setting, DTZ further intensifies the nephrotoxicity of BJP as well as some but not all filterable proteins.Effet du pH urinaire et du diatrizoate sur la néphrotoxicité de la protéine de Bence Jones chez le rat. Un pH urinaire bas et les produits de contraste peuvent accroître la néphrotoxité du myélome. Pour étudier les effets de ces facteurs, nous avons déterminé les clearances de l'inuline (CIn) avant et après perfusion de protéine de Bence Jones humaine (BJP) chez des rats mâles Sprague-Dawley à dose préalablement montrée néphrotoxique. Les rats qui buvaient 0,15 M NaHCO3 pendant 48 hr avant l'étude n'avaient pas de modification de CIn (+ 3 ± 20%) après BJP à la différence de ceux qui buvaient 0,15 M NH4Cl (- 33 ± 14%, P < 0,05); les pH urinaires différaient (7,6 ± 0,1 contre 6,2 ± 0,1, P < 0,05), mais non les débits urinaires. Le régime acidifiant a été utilisé chez tous les groupes ultérieurs. La perfusion de diatrizoate (DTZ) après BJP a entraîné une diminution supplémentaire de CIn (- 85 ± 8%, P < 0,05). A l'opposé une perfusion d'albumine, qui augmentait la protidémie à la valeur observée chez les rats perfusés avec BJP ne modifiait pas CIn (+ 39 ± 17%). Une perfusion de béta-lactoglobuline a également entraîné une plus forte baisse de CIn après DTZ (- 35 ± 9 contre - 67 ± 8%, P < 0,05), mais non de la myoglobine (- 58 ± 7 contre - 54 ± 12%). Le pH et le débit urinaires ne différaient pas entre aucun des groupes perfusés par le DTZ et leur contrôle approprié. Ces données suggèrent que l'acidurie, indépendamment du débit urinaire, augmente la néphrotoxicité de la BJP. Dans ce schéma, DTZ accentue encore la néphrotoxicité de la BJP, de même que certaines, mais non toutes les protéines filtrables

    An integrated framework for solid modeling and structural analysis of layered composites with defects

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    Laminated fiber-reinforced polymer (FRP) composites are widely used in aerospace and automotive industries due to their combined properties of high strength and low weight. However, owing to their complex structure, it is difficult to assess the impact of manufacturing defects and service damage on their residual life. Non-destructive evaluation (NDE) of composites using ultrasonic testing (UT) can identify the presence of defects. However, manually incorporating the damage in a CAD model of a multi-layered composite structure and evaluating its structural integrity is a tedious process. We have developed an automated framework to create a layered 3D CAD model of a composite structure and automatically preprocess it for structural finite element (FE) analysis. In addition, we can incorporate flaws and known composite damage automatically into this CAD model. The framework generates a layer-by-layer 3D structural CAD model of the composite laminate, replicating its manufacturing process. The framework can create non-trivial composite structures such as those that include stiffeners. Outlines of structural defects, such as delaminations detected using UT of the laminate, are incorporated into the CAD model between the appropriate layers. The framework is also capable of incorporating fiber/matrix cracking, another common defect observed in fiber-reinforced composites. Finally, the framework can preprocess the resulting 3D CAD models with defects for direct structural analysis by automatically applying the appropriate boundary conditions. In this paper, we show a working proof-of-concept of the framework with capabilities of creating composite structures with stiffeners, incorporating delaminations between the composite layers, and automatically preprocessing the CAD model for finite element structural analysis. The framework will ultimately aid in accurately assessing the residual life of the composite and making informed decisions regarding repairs

    Results of the 2016 Indianapolis Biodiversity Survey, Marion County, Indiana

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    Surprising biodiversity can be found in cities, but urban habitats are understudied. We report on a bioblitz conducted primarily within a 24-hr period on September 16 and 17, 2016 in Indianapolis, Indiana, USA. The event focused on stretches of three waterways and their associated riparian habitat: Fall Creek (20.6 ha; 51 acres), Pleasant Run (23.5 ha; 58 acres), and Pogue’s Run (27.1 ha; 67 acres). Over 75 scientists, naturalists, students, and citizen volunteers comprised 14 different taxonomic teams. Five hundred ninety taxa were documented despite the rainy conditions. A brief summary of the methods and findings are presented here. Detailed maps of survey locations and inventory results are available on the Indiana Academy of Science website (https://www.indianaacademyofscience.org/)

    A Database of Cepheid Distance Moduli and TRGB, GCLF, PNLF and SBF Data Useful for Distance Determinations

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    We present a compilation of Cepheid distance moduli and data for four secondary distance indicators that employ stars in the old stellar populations: the planetary nebula luminosity function (PNLF), the globular cluster luminosity function (GCLF), the tip of the red giant branch (TRGB), and the surface brightness fluctuation (SBF) method. The database includes all data published as of July 15, 1999. The main strength of this compilation resides in all data being on a consistent and homogeneous system: all Cepheid distances are derived using the same calibration of the period-luminosity relation, the treatment of errors is consistent for all indicators, measurements which are not considered reliable are excluded. As such, the database is ideal for inter-comparing any of the distance indicators considered, or for deriving a Cepheid calibration to any secondary distance indicator. Specifically, the database includes: 1) Cepheid distances, extinctions and metallicities; 2) apparent magnitudes of the PNLF cutoff; 3) apparent magnitudes and colors of the turnover of the GCLF (both in the V- and B-bands); 4) apparent magnitudes of the TRGB (in the I-band) and V-I colors at and 0.5 magnitudes fainter than the TRGB; 5) apparent surface brightness fluctuation magnitudes I, K', K_short, and using the F814W filter with the HST/WFPC2. In addition, for every galaxy in the database we give reddening estimates from DIRBE/IRAS as well as HI maps, J2000 coordinates, Hubble and T-type morphological classification, apparent total magnitude in B, and systemic velocity. (Abridged)Comment: Accepted for publication in the Astrophysical Journal Supplement Series. Because of space limitations, the figures included are low resolution bitmap images. Original figures can be found at http://www.astro.ucla.edu/~laura/pub.ht
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