142 research outputs found
How effective is the early support program Babylotse-Plus for psychosocially burdened mothers and their infants? A comparative intervention study
Objectives:
Our aim was to examine the effects of an early perinatal prevention program offered to mothers and families suffering from significant psychosocial burden.
Methods:
All mothers giving birth in a Berlin university hospital during Jan-Aug 2013 were screened with a standardized 27-item questionnaire by trained staff. Mothers with a screening-score ≥ 3, who were not enrolled in other public support programs, were defined as psychosocially burdened. They received a detailed needs assessment and were followed up with counseling. When necessary, affected mothers were voluntarily guided through to specialized 'early support' institutions during the 12-month-intervention period. The historical control group (care-as-usual) consisted of children born at the same hospital the year before.At 12 months postnatally, we interviewed mothers in both groups to assess their stress burden and coping skills by Parenting Stress Index and assessed the current childcare condition. Differences between the groups were compared by multivariable logistic regression analyses adjusting for potential confounders.
Results:
The intervention group and the control group included 225 and 157 families, respectively. After 12-months, mothers in the 'early support' intervention group had significantly less often depression (adjusted odds ratio 0.25, 95%-confidence interval 0.07-0.94), less often a disturbed relationship with the parenting partner (0.34, 0.10-1.14) and reported reduced stress due to the child's demands (0.40, 0.15-1.10) compared to the control group. Childcare indicators did not differ between the 2 groups.
Conclusions:
In mothers at high psychosocial risk, the 'early support' intervention program Babylotse-Plus seemed to reduce the occurrence of depression and several stress indicators in the first postnatal year
RNAi-mediated suppression of isoprene emission in poplar transiently impacts phenolic metabolism under high temperature and high light intensities: a transcriptomic and metabolomic analysis
In plants, isoprene plays a dual role: (a) as thermo-protective agent proposed to prevent degradation of enzymes/membrane structures involved in photosynthesis, and (b) as reactive molecule reducing abiotic oxidative stress. The present work addresses the question whether suppression of isoprene emission interferes with genome wide transcription rates and metabolite fluxes in grey poplar (Populusxcanescens) throughout the growing season. Gene expression and metabolite profiles of isoprene emitting wild type plants and RNAi-mediated non-isoprene emitting poplars were compared by using poplar Affymetrix microarrays and non-targeted FT-ICR-MS (Fourier transform ion cyclotron resonance mass spectrometry). We observed a transcriptional down-regulation of genes encoding enzymes of phenylpropanoid regulatory and biosynthetic pathways, as well as distinct metabolic down-regulation of condensed tannins and anthocyanins, in non-isoprene emitting genotypes during July, when high temperature and light intensities possibly caused transient drought stress, as indicated by stomatal closure. Under these conditions leaves of non-isoprene emitting plants accumulated hydrogen peroxide (H2O2), a signaling molecule in stress response and negative regulator of anthocyanin biosynthesis. The absence of isoprene emission under high temperature and light stress resulted transiently in a new chemo(pheno)type with suppressed production of phenolic compounds. This may compromise inducible defenses and may render non-isoprene emitting poplars more susceptible to environmental stress
B-flavor tagging at Belle II
We report on new flavor tagging algorithms developed to determine the quark-flavor content of bottom ( ) mesons at Belle II. The algorithms provide essential inputs for measurements of quark-flavor mixing and charge-parity violation. We validate and evaluate the performance of the algorithms using hadronic decays with flavor-specific final states reconstructed in a data set corresponding to an integrated luminosity of 62.8 fb−1
, collected at the resonance with the Belle II detector at the SuperKEKB collider. We measure the total effective tagging efficiency to be
εeff=(30.0±1.2(stat)±0.4(syst))%
for a category-based algorithm and
εeff=(28.8±1.2(stat)±0.4(syst))%
for a deep-learning-based algorithm
Measurement of the lifetime
An absolute measurement of the lifetime is reported using
decays in events reconstructed from data
collected by the Belle II experiment at the SuperKEKB asymmetric-energy
electron-positron collider. The total integrated luminosity of the data sample,
which was collected at center-of-mass energies at or near the
resonance, is 207.2~\mbox{fb}^{-1}. The result, fs, is the most precise
measurement to date and is consistent with previous determinations.Comment: Accepted for publication in PR
Search for an invisible in a final state with two muons and missing energy at Belle II
The extension of the standard model predicts the existence
of a lepton-flavor-universality-violating boson that couples only
to the heavier lepton families. We search for such a through its
invisible decay in the process . We use a
sample of electron-positron collisions at a center-of-mass energy of 10.58GeV
collected by the Belle II experiment in 2019-2020, corresponding to an
integrated luminosity of 79.7fb. We find no excess over the expected
standard-model background. We set 90-confidence-level upper limits on the
cross section for this process as well as on the coupling of the model, which
ranges from at low masses to 1 at
masses of 8
Precise Measurement of the D and D Lifetimes at Belle II
We report a measurement of the D and D lifetimes using D→Kπ and D→Kππ decays reconstructed in ee→ data recorded by the Belle II experiment at the SuperKEKB asymmetric-energy ee collider. The data, collected at center-of-mass energies at or near the Υ(4S) resonance, correspond to an integrated luminosity of 72 fb. The results, τ(D)=410.5±1.1(stat)±0.8(syst) fs and τ(D)=1030.4±4.7(stat)±3.1(syst) fs, are the most precise to date and are consistent with previous determinations
Measurement of the branching fraction and asymmetry of decays using pairs in Belle II data
We report measurements of the branching fraction and asymmetry in
decays reconstructed at Belle II in an
electron-positron collision sample containing
pairs. We measure a branching fraction \mathcal{B}(\Bpipi) =
(1.38 \pm 0.27 \pm 0.22) \times 10^{-6} and a asymmetry \Acp(\Bpipi)
= 0.14 \pm 0.46 \pm 0.07, where the first uncertainty is statistical and the
second is systematic
Search for a resonance in events with the Belle II experiment
We report the first search for a non-standard-model resonance decaying into
pairs in events in
the 3.6-10 GeV/ mass range. We use a 62.8 fb sample of
collisions collected at a center-of-mass energy of 10.58 GeV by the Belle II
experiment at the SuperKEKB collider. The analysis probes three different
models predicting a spin-1 particle coupling only to the heavier lepton
families, a Higgs-like spin-0 particle that couples preferentially to charged
leptons (leptophilic scalar), and an axion-like particle, respectively. We
observe no evidence for a signal and set exclusion limits at 90% confidence
level on the product of cross section and branching fraction into pairs,
ranging from 0.7 fb to 24 fb, and on the couplings of these processes. We
obtain world-leading constraints on the couplings for the leptophilic scalar
model for masses above 6.5 GeV/ and for the axion-like particle model over
the entire mass range
Observation of decays using the 2019-2022 Belle II data sample
We present a measurement of the branching fractions of four decay modes. The measurement is based on data from
SuperKEKB electron-positron collisions at the resonance
collected with the Belle II detector and corresponding to an integrated
luminosity of . The event yields are extracted from fits
to the distributions of the difference between expected and observed meson
energy to separate signal and background, and are efficiency-corrected as a
function of the invariant mass of the system. We find the branching
fractions to be: where the first uncertainty is statistical and
the second systematic. These results include the first observation of
, , and decays and a significant improvement in the precision
of compared to previous measurements
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