The faint-galaxy hosts of gamma-ray bursts

The observed redshifts and magnitudes of the host galaxies of gamma-ray bursts (GRBs) are compared with the predictions of three basic GRB models, in which the comoving rate density of GRBs is (1) proportional to the cosmic star formation rate density, (2) proportional to the total integrated stellar density and (3) constant. All three models make the assumption that at every epoch the probability of a GRB occuring in a galaxy is proportional to that galaxy's broad-band luminosity. No assumption is made that GRBs are standard candles or even that their luminosity function is narrow. All three rate density models are consistent with the observed GRB host galaxies to date, although model (2) is slightly disfavored relative to the others. Models (1) and (3) make very similar predictions for host galaxy magnitude and redshift distributions; these models will be probably not be distinguished without measurements of host-galaxy star-formation rates. The fraction of host galaxies fainter than 28 mag may constrain the faint end of the galaxy luminosity function at high redshift, or, if the fraction is observed to be low, may suggest that the bursters are expelled from low-luminosity hosts. In all models, the probability of finding a z<0.008 GRB among a sample of 11 GRBs is less than 10^(-4), strongly suggesting that GRB 980425, if associated with supernova 1998bw, represents a distinct class of GRBs.Comment: 7 pages, ApJ in press, revised to incorporate yet more new and revised observational result

Acute Spinal Cord Injury: Correlations and Causal Relations Between Intraspinal Pressure, Spinal Cord Perfusion Pressure, Lactate-to-Pyruvate Ratio, and Limb Power.

BACKGROUND/OBJECTIVE: We have recently developed monitoring from the injury site in patients with acute, severe traumatic spinal cord injuries to facilitate their management in the intensive care unit. This is analogous to monitoring from the brain in patients with traumatic brain injuries. This study aims to determine whether, after traumatic spinal cord injury, fluctuations in the monitored physiological, and metabolic parameters at the injury site are causally linked to changes in limb power. METHODS: This is an observational study of a cohort of adult patients with motor-incomplete spinal cord injuries, i.e., grade C American spinal injuries association Impairment Scale. A pressure probe and a microdialysis catheter were placed intradurally at the injury site. For up to a week after surgery, we monitored limb power, intraspinal pressure, spinal cord perfusion pressure, and tissue lactate-to-pyruvate ratio. We established correlations between these variables and performed Granger causality analysis. RESULTS: Nineteen patients, aged 22-70 years, were recruited. Motor score versus intraspinal pressure had exponential decay relation (intraspinal pressure rise to 20 mmHg was associated with drop of 11 motor points, but little drop in motor points as intraspinal pressure rose further, R2 = 0.98). Motor score versus spinal cord perfusion pressure (up to 110 mmHg) had linear relation (1.4 motor point rise/10 mmHg rise in spinal cord perfusion pressure, R2 = 0.96). Motor score versus lactate-to-pyruvate ratio (greater than 20) also had linear relation (0.8 motor score drop/10-point rise in lactate-to-pyruvate ratio, R2 = 0.92). Increased intraspinal pressure Granger-caused increase in lactate-to-pyruvate ratio, decrease in spinal cord perfusion, and decrease in motor score. Increased spinal cord perfusion Granger-caused decrease in lactate-to-pyruvate ratio and increase in motor score. Increased lactate-to-pyruvate ratio Granger-caused increase in intraspinal pressure, decrease in spinal cord perfusion, and decrease in motor score. Causality analysis also revealed multiple vicious cycles that amplify insults to the cord thus exacerbating cord damage. CONCLUSION: Monitoring intraspinal pressure, spinal cord perfusion pressure, lactate-to-pyruvate ratio, and intervening to normalize these parameters are likely to improve limb power

Interleukin-12 p40 secretion by cutaneous CD11c(+) and F4/80(+) cells is a major feature of the innate immune response in mice that develop Th1-mediated protective immunity to Schistosoma mansoni

Radiation-attenuated (RA) schistosome larvae are potent stimulators of innate immune responses at the skin site of exposure (pinna) that are likely to be important factors in the development of Th1-mediated protective immunity. In addition to causing an influx of neutrophils, macrophages, and dendritic cells (DCs) into the dermis, RA larvae induced a cascade of chemokine and cytokine secretion following in vitro culture of pinna biopsy samples. While macrophage inflammatory protein 1alpha and interleukin-1beta (IL-1beta) were produced transiently within the first few days, the Th1-promoting cytokines IL-12 and IL-18 were secreted at high levels until at least day 14. Assay of C3H/HeJ mice confirmed that IL-12 secretion was not due to lipopolysaccharide contaminants binding Toll-like receptor 4. Significantly, IL-12 p40 secretion was sustained in pinnae from vaccinated mice but not in those from nonprotected infected mice. In contrast, IL-10 was produced from both vaccinated and infected mice. This cytokine regulates IL-12-associated dermal inflammation, since in vaccinated IL-10(-/-) mice, pinna thickness was greatly increased concurrent with elevated levels of IL-12 p40. A significant number of IL-12 p40(+) cells were detected as emigrants from in vitro-cultured pinnae, and most were within a population of rare large granular cells that were Ia(+), consistent with their being antigen-presenting cells. Labeling of IL-12(+) cells for CD11c, CD205, CD8alpha, CD11b, and F4/80 indicated that the majority were myeloid DCs, although a proportion were CD11c(-) F4/80(+), suggesting that macrophages were an additional source of IL-12 in the skin

The effect of structure formation on the expansion of the universe

Observations of the expansion rate of the universe at late times disagree by a factor of 1.5-2 with the prediction of homogeneous and isotropic models based on ordinary matter and gravity. We discuss how the departure from linearly perturbed homogeneity and isotropy due to structure formation could explain this discrepancy. We evaluate the expansion rate in a dust universe which contains non-linear structures with a statistically homogeneous and isotropic distribution. The expansion rate is found to increase relative to the exactly homogeneous and isotropic case by a factor of 1.1-1.3 at some tens of billion of years. The timescale follows from the cold dark matter transfer function and the amplitude of primordial perturbations without additional free parameters.Comment: 6 pages, 1 figure. Awarded Honorable Mention in the 2008 Gravity Research Foundation essay competition. More extended treatment of the topics can be found in arXiv:0801.2692v

Training and Turnover in Organizations

We present a two-level model of organizational training and agent production. Managers decide whether or not to train based on both the costs of training compared to the benefits and on their expectations and observations of the number of other firms that also train. Managers also take into account the sum of their employees' contributions and the average tenure length within their organization. Employees decide whether or not to contribute to production based on their expectations as to how other employees will act. Trained workers learn over time and fold their increased productivity into their decision whether or not to contribute. We find that the dynamical behavior at the two levels is closely coupled: the evolution of the industry over time depends not only on the characteristics of training programs, learning curves, and cost-benefit analyses, but on the vagaries of chance as well. For example, in one case, the double dilemma can be resolved for the industry as a whole and productivity then increases steadily over time. In another, the organizational level dilemma may remain unresolved and workers may contribute at fluctuating levels. In this case the overall productivity stays low. We also find a correlation between high productivity and low turnover and show that a small increase in training rates can lead to explosive growth in productivity.Comment: 9 pages. Also available through anonymous ftp from parcftp.xerox.com in the directory pub/dynamics as training.p

The dependence on morphology of the gas content in galactic disks

The classification S0 was introduced by Hubble to serve as a description of galaxies whose morphological characteristics seemed to lie between the disk-dominated spirals and the spheroidal elliptical systems. Since then there has been extensive discussion as to whether this classification sequence is also an evolutionary sequence. Many studies have focussed on a particular feature such as the luminosity profile, the bulge-to-disk ratio, or the nature of the interstellar matter, but the question of the evolution remains contentious. Equally contentious is the question of the classification itself. For systems with well-developed disks there usually is no problem. Many spheroidal systems also are unambiguously classified as ellipticals in most catalogs. However, there are a number of early systems which have been reclassified following review using improved optical material. For example, Eder et al. (AJ, 102, 572, 1991) found that many of the S0 galaxies which are rich in neutral hydrogen have faint spiral features. The confusion about classification propagates into the discussion of the properties of early-type systems. Attempts to put the classification system on a quantitative basis have in general been unsuccessful. Recently Sandage (private communication) has reviewed the classification of early systems and has defined a set of sub-classes for these objects. The S0 galaxies are divided into three groups, depending on the prominence of the disk. There are six subdivisions of Sa galaxies, depending upon the relative prominence of knots and other arm-like characteristics. We have explored the total gas content in these objects to see if there is a dependence on the galaxy morphology, as denoted by these new subclasses

Screen Barriers for Reducing Interplot Movement of Three Adult Plant Bug (Hemiptera: Miridae) Species in Small Plot Experiments

Fiberglass screen barriers 1.2 m high were erected around small (7.3 x 3.7 m) plots of birdsfoot trefoil, Lotus corniculatus, to study the effectiveness of screen barriers in reducing adult plant bug migration into small field plots. Screened and unscreened (control) plots were sprayed with an insecticide at the onset of the experiment, and subsequent adult mirid migration into these trefoil plots was measured by sweep net samples during the following 24 day period. Combined adult Adelphocoris lineolatus, Lygus lineolaris, and Plagiognathus chrysanthemi densities were significantly lower in screened versus unscreened plots with 37070, 28010, and 23070 fewer adults at 7, 17, and 24 days, respectively, following insecticide application. Although these barriers were inexpensive and simple to construct, we conclude that they were not practical and effective enough for reducing adult mirid migration in small plot experiments of this type

Survival, Development and Population Dynamics of \u3ci\u3eEmpoasca Fabae\u3c/i\u3e (Homoptera: Cicadellidae) on Three Legume Hosts

Survival and development of potato leafhopper, Empoasca fabae, nymphs were measured on alfalfa (Medicago sativa), birdsfoot trefoil (Lotus corniculatus), and red clover (Trifolium pratense). Survival was not significantly different among host plants (mean = 62%). There was no interaction between sex and host plant for developmental time. Males developed significantly faster than females. Developmental time was fastest on alfalfa, intermediate on trefoil, and slowest on red clover. Plots of alfalfa, trefoil, and red clover were planted to compare the seasonal abundance of the potato leafhopper in the three forages. Nymphs were more abundant in trefoil than in alfalfa and red clover late in July, but no differences occurred on the other sample dates. At their peak, adults were more abundant in alfalfa than in trefoil and red clover