25,417 research outputs found
VR/Urban: SMSlingshot
In this paper we describe the concept and design objectives of VR/Urban's media intervention tool SMSlingshot, which was presented at the Riga White Night Arts Festival 2009 for the first time
Telehealth methods to deliver multifactorial dietary interventions in adults with chronic disease: A systematic review protocol
Background: The long-term management of chronic diseases requires adoption of complex dietary recommendations, which can be facilitated by regular coaching to support sustained behaviour change. Telehealth interventions can overcome patient-centred barriers to accessing face-to-face programs and provide feasible delivery methods, ubiquitous and accessible regardless of geographic location. The protocol for this systematic review explains the methods that will be utilised to answer the review question of whether telehealth interventions are effective at promoting change in dietary intake and improving diet quality in people with chronic disease. Methods/design: A structured search of Medline, EMBASE, CINAHL, and PsychINFO, from their inception, will be conducted. We will consider randomised controlled trials which evaluate complex dietary interventions in adults with chronic disease. Studies must provide diet education in an intervention longer than 4 weeks in duration, and at least half of the intervention contact must be delivered via telehealth. Comparisons will be made against usual care or a non-telehealth intervention. The primary outcome of interest is dietary change with secondary outcomes relating to clinical markers pre-specified in the methodology. The process for selecting studies, extracting data, and resolving conflicts will follow a set protocol. Two authors will independently appraise the studies and extract the data, using specified methods. Meta-analyses will be conducted where appropriate, with parameters for determining statistical heterogeneity pre-specified. The GRADE tool will be used for determining the quality of evidence for analysed outcomes. Discussion: To date, there has been a considerable variability in the strategies used to deliver dietary education, and the overall effectiveness of telehealth dietary interventions for facilitating dietary change has not been reviewed systematically in adults with chronic disease. A systematic synthesis of telehealth strategies will inform the development of evidence-based telehealth programs that can be tailored to deliver dietary interventions specific to chronic disease conditions. Systematic review registration: PROSPERO CRD42015026398
Enhancement of perfluorooctanoate and perfluorooctanesulfonate activity at acoustic cavitation bubble interfaces
Acoustic cavitation driven by ultrasonic irradiation decomposes and mineralizes the recalcitrant perfluorinated surfactants perfluorooctanesulfonate (PFOS) and perfluorooctanoate (PFOA). Pyrolytic cleavage of the ionic headgroup is the rate-determining step. In this study, we examine the sonochemical adsorption of PFOX, where X = S for PFOS and A for PFOA, by determining kinetic order and absolute rates over an initial PFOX concentration range of 20 nM to 200 μM. Sonochemical PFOX kinetics transition from pseudo-first-order at low initial concentrations, [PFOX]_i 40 μM, as the bubble interface sites are saturated. At PFOX concentrations below 100 μM, concentration-dependent rates were modeled with Langmuir−Hinshelwood (LH) kinetics. Empirically determined rate maximums, V_(Max)^(−PFOA) = 2230 ± 560 nM min^−1 and V_(Max)^(−PFOS) = 230 ± 60 nM min^−1, were used in the LH model, and sonochemical surface activities were estimated to be K_(Sono)^(PFOS) = 120000 M^−1 and K_(Sono)^(PFOA) = 28500 M^−1, 60 and 80 times greater than equilibrium surface activities, K_(Eq)^(PFOS) and K_(Eq)^(PFOA). These results suggest enhanced sonochemical degradation rates for PFOX when the bubble interface is undersaturated. The present results are compared to previously reported sonochemical kinetics of nonvolatile surfactants
Evidence for a brown adipocyte specific enhancer in the first intron of the murine Ucp3 gene
Analytic structure of solutions to multiconfiguration equations
We study the regularity at the positions of the (fixed) nuclei of solutions
to (non-relativistic) multiconfiguration equations (including Hartree--Fock) of
Coulomb systems. We prove the following: Let {phi_1,...,phi_M} be any solution
to the rank--M multiconfiguration equations for a molecule with L fixed nuclei
at R_1,...,R_L in R^3. Then, for any j in {1,...,M} and k in {1,...,L}, there
exists a neighbourhood U_{j,k} in R^3 of R_k, and functions phi^{(1)}_{j,k},
phi^{(2)}_{j,k}, real analytic in U_{j,k}, such that phi_j(x) =
phi^{(1)}_{j,k}(x) + |x - R_k| phi^{(2)}_{j,k}(x), x in U_{j,k} A similar
result holds for the corresponding electron density. The proof uses the
Kustaanheimo--Stiefel transformation, as applied earlier by the authors to the
study of the eigenfunctions of the Schr"odinger operator of atoms and molecules
near two-particle coalescence points.Comment: 15 page
Comparative evaluation of insecticide efficacy tests against Drosophila suzukii on grape berries in laboratory, semi-field and field trials
As the period for field trials on grapevine is limited, we designed a laboratory test system to evaluate the effectiveness of selected insecticides against spotted-wing Drosophila (SWD), Drosophila suzukii, on different types of grape berries all year round. Tests were undertaken during winter and early spring with table grapes of different purchased varieties according to their seasonal availability and with wine grapes from experimental field plots in autumn. In preliminary experiments, we defined parameters for a standard laboratory test system for screening the effectiveness of several formulated insecticides in two different experimental set-ups: i) application before confining adults with berries and ii) application after confining adult D. suzukii with berries. These approaches allowed us to determine the contact activity of the products on adult D. suzukii or the impact on the larval development until the emergence of adult flies. The developed test system is suitable for screening substances with diverse types of activity on different grape types. In a second step, we combined laboratory bioassays with field applications in a semi-field persistence study and lastly we installed a randomized field plot in order to compare the effectiveness of selected insecticides in the laboratory and under field conditions. In all cases, the products Karate Zeon and SpinTor proved most efficacious in their contact mortality or as oviposition deterrents, while Mospilan SG and Coragen exhibited a good larvicidal activity. However, important disagreements occurred for the efficacy of currently authorized insecticides among laboratory, semi-field and practical field applications. The transferability of laboratory results into the field is discussed
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