21,882 research outputs found
Centrifugally Obtained Artificial Gravity
Centrifugally obtained artificial gravity effects on space station crew performanc
Coherent Excitation of the 6S1/2 to 5D3/2 Electric Quadrupole Transition in 138Ba+
The electric dipole-forbidden, quadrupole 6S1/2 5D3/2 transition in Ba+
near 2051 nm, with a natural linewidth of 13 mHz, is attractive for potential
observation of parity non-conservation, and also as a clock transition for a
barium ion optical frequency standard. This transition also offers a direct
means of populating the metastable 5D3/2 state to measure the nuclear magnetic
octupole moment in the odd barium isotopes. Light from a diode-pumped, solid
state Tm,Ho:YLF laser operating at 2051 nm is used to coherently drive this
transition between resolved Zeeman levels in a single trapped 138Ba+ ion. The
frequency of the laser is stabilized to a high finesse Fabry Perot cavity at
1025 nm after being frequency doubled. Rabi oscillations on this transition
indicate a laser-ion coherence time of 3 ms, most likely limited by ambient
magnetic field fluctuations.Comment: 5 pages, 5 figure
The role of social cognition in decision making
Successful decision making in a social setting depends on our ability to understand the intentions, emotions and beliefs of others. The mirror system allows us to understand other people's motor actions and action intentions. ‘Empathy’ allows us to understand and share emotions and sensations with others. ‘Theory of mind’ allows us to understand more abstract concepts such as beliefs or wishes in others. In all these cases, evidence has accumulated that we use the specific neural networks engaged in processing mental states in ourselves to understand the same mental states in others. However, the magnitude of the brain activity in these shared networks is modulated by contextual appraisal of the situation or the other person. An important feature of decision making in a social setting concerns the interaction of reason and emotion. We consider four domains where such interactions occur: our sense of fairness, altruistic punishment, trust and framing effects. In these cases, social motivations and emotions compete with each other, while higher-level control processes modulate the interactions of these low-level biases
On-board processing for future satellite communications systems: Satellite-Routed FDMA
A frequency division multiple access (FDMA) 30/20 GHz satellite communications architecture without on-board baseband processing is investigated. Conceptual system designs are suggested for domestic traffic models totaling 4 Gb/s of customer premises service (CPS) traffic and 6 Gb/s of trunking traffic. Emphasis is given to the CPS portion of the system which includes thousands of earth terminals with digital traffic ranging from a single 64 kb/s voice channel to hundreds of channels of voice, data, and video with an aggregate data rate of 33 Mb/s. A unique regional design concept that effectively smooths the non-uniform traffic distribution and greatly simplifies the satellite design is employed. The satellite antenna system forms thirty-two 0.33 deg beam on both the uplinks and the downlinks in one design. In another design matched to a traffic model with more dispersed users, there are twenty-four 0.33 deg beams and twenty-one 0.7 deg beams. Detailed system design techniques show that a single satellite producing approximately 5 kW of dc power is capable of handling at least 75% of the postulated traffic. A detailed cost model of the ground segment and estimated system costs based on current information from manufacturers are presented
Unfolding cross-linkers as rheology regulators in F-actin networks
We report on the nonlinear mechanical properties of a statistically
homogeneous, isotropic semiflexible network cross-linked by polymers containing
numerous small unfolding domains, such as the ubiquitous F-actin cross-linker
Filamin.
We show that the inclusion of such proteins has a dramatic effect on the
large strain behavior of the network. Beyond a strain threshold, which depends
on network density, the unfolding of protein domains leads to bulk shear
softening. Past this critical strain, the network spontaneously organizes
itself so that an appreciable fraction of the Filamin cross-linkers are at the
threshold of domain unfolding. We discuss via a simple mean-field model the
cause of this network organization and suggest that it may be the source of
power-law relaxation observed in in vitro and in intracellular microrheology
experiments. We present data which fully justifies our model for a simplified
network architecture.Comment: 11 pages, 4 figures. to appear in Physical Review
Second year technical report on-board processing for future satellite communications systems
Advanced baseband and microwave switching techniques for large domestic communications satellites operating in the 30/20 GHz frequency bands are discussed. The nominal baseband processor throughput is one million packets per second (1.6 Gb/s) from one thousand T1 carrier rate customer premises terminals. A frequency reuse factor of sixteen is assumed by using 16 spot antenna beams with the same 100 MHz bandwidth per beam and a modulation with a one b/s per Hz bandwidth efficiency. Eight of the beams are fixed on major metropolitan areas and eight are scanning beams which periodically cover the remainder of the U.S. under dynamic control. User signals are regenerated (demodulated/remodulated) and message packages are reformatted on board. Frequency division multiple access and time division multiplex are employed on the uplinks and downlinks, respectively, for terminals within the coverage area and dwell interval of a scanning beam. Link establishment and packet routing protocols are defined. Also described is a detailed design of a separate 100 x 100 microwave switch capable of handling nonregenerated signals occupying the remaining 2.4 GHz bandwidth with 60 dB of isolation, at an estimated weight and power consumption of approximately 400 kg and 100 W, respectively
Point-of-Care Diagnostic Device for the Quantitative Analysis of Human Estradiol at Low-Picomolar Concentrations
A fundamental issue in healthcare is the development of cost-effective and reliable diagnostic assays. While still a relatively new field, paper-based analytical devices are emerging as inexpensive and portable methods of providing healthcare professionals with real-time diagnostic information. Furthermore, these devices can often be used at the point of care, thus eliminating the need for a myriad of time-consuming laboratory techniques. While the original goal of this project was to develop a paper-based lateral flow immunoassay capable of colorimetric quantitation, the device design was altered over the course of the past year. Upon testing, the originally proposed lateral flow assay lacked adequate sensitivity and reliability. Therefore, a novel three-dimensional paper-based analytical device was developed. This new device design utilizes enzymatic amplification to break down a biomatrix, ultimately producing a chronometric readout. This unique biomatrix can detect \u3c1 femtomole (10-15) of analyte, with degradation time being directly correlated to analyte concentration. Thus far, device storage conditions, viable pH ranges, and viable temperature ranges have been determined. While further refinement is still needed, these diagnostic devices have the potential to revolutionize point-of-care assays through the quantification of analytes in both field and clinical settings
- …