Super Sudoku Squares

We refer to a completed Sudoku puzzle as a Sudoku Square of order 3. We define a more restricted, but natural, extension --- a Super Sudoku Square of order n, and determine for which orders n one exists

Enterprise Resource Planning (ERP) : a case study of Space and Naval Warfare Systems Center San Diego's Project Cabrillo

This thesis examines the Enterprise Resource Planning (ERP) pilot implementation conducted at the Space and Naval Warfare Systems Center San Diego (SSC-SD), the first of four Department of the Navy (DON) pilot implementations. Specifically, comparisons are drawn between both successful and unsuccessful ERP implementations within private sector organizations and that of SSC-SD. Any commonalities in implementation challenges could be applied to future ERP implementations in both the DON and Department of Defense (DOD). The findings are based in part upon interviews and data collected. From the comparison, commonalities exist in ERP implementation challenges between private sector organizations and SSC-SD. Additionally the management techniques used to mitigate those challenges are similar. Finally, due to SSC-SD's financial management structure and appropriated funding constraints, unique obstacles were identified during the implementation. These unique obstacles will be encountered by other Working Capital Funded (WCF) organizations planning to implement ERP on the same scale as SSC-SD. This thesis supports that the implementation of ERP at SSC-SD was a success based on industry comparisons, the goals of Project Cabrillo's business case analysis (BCA), and its Chief Financial Officer (CFO) Act compliancy assessment, January 2002.http://archive.org/details/enterpriseresour109454714Lieutenant Commander, United States NavyCaptain, United States ArmyApproved for public release; distribution is unlimited

Application of an Extremal Result of Erdős and Gallai to the (n,k,t) Problem

An extremal result about vertex covers, attributed by Hajnal to Erdős and Gallai, is applied to prove the following: If n, k, and t are integers satisfying n ≥ k ≥ t ≥ 3 and k ≤ 2t - 2, and G is a graph with the minimum number of edges among graphs on n vertices with the property that every induced subgraph on k vertices contains a complete subgraph on t vertices, then every component of G is complete

Electron Transfer Precedes ATP Hydrolysis during Nitrogenase Catalysis

The biological reduction of N2 to NH3 catalyzed by Mo-dependent nitrogenase requires at least eight rounds of a complex cycle of events associated with ATP-driven electron transfer (ET) from the Fe protein to the catalytic MoFe protein, with each ET coupled to the hydrolysis of two ATP molecules. Although steps within this cycle have been studied for decades, the nature of the coupling between ATP hydrolysis and ET, in particular the order of ET and ATP hydrolysis, has been elusive. Here, we have measured first-order rate constants for each key step in the reaction sequence, including direct measurement of the ATP hydrolysis rate constant: kATP = 70 s−1, 25 °C. Comparison of the rate constants establishes that the reaction sequence involves four sequential steps: (i) conformationally gated ET (kET = 140 s−1, 25 °C), (ii) ATP hydrolysis (kATP = 70 s−1, 25 °C), (iii) Phosphate release (kPi = 16 s−1, 25 °C), and (iv) Fe protein dissociation from the MoFe protein (kdiss = 6 s−1, 25 °C). These findings allow completion of the thermodynamic cycle undergone by the Fe protein, showing that the energy of ATP binding and protein–protein association drive ET, with subsequent ATP hydrolysis and Pi release causing dissociation of the complex between the Feox(ADP)2 protein and the reduced MoFe protein

Irrigation Systems Management

Like most textbooks, this book grew out of our desire to have written material that matches the educational needs of both the students and the instructor of a college course, in this case a course entitled Irrigation Systems Management. The book is the culmination of course notes which have been in development and use for nearly 30 years. The emphasis of this book is on the management of irrigation systems that are used for agricultural crop production. There are two distinct components of the book, starting with the soil-water-plant-atmosphere system and how soil water should be managed to achieve the desired crop production outcomes. This includes in-depth presentations on soil water storage and movement, plant water use, managing the soil water reservoir through irrigation scheduling, and salinity management. The book then shifts to the second component, which is the description and management of the various forms of agricultural irrigation systems along with their water supply. Whether it be a surface, sprinkler, or microirrigation system, the irrigation manager must not only know how much water to apply but also how to manage the system itself to achieve efficient application. High application efficiency can only be realized by minimizing runoff, deep percolation, evaporation, and drift onto non-target areas. Since energy costs are an integral part of the management equation, one chapter in the book deals with the hydraulics and energy requirements of pumping and distributing water. One of the key themes spread throughout the book is providing guidance to irrigation managers on how to improve irrigation water productivity (production per unit of irrigation water) and minimize water resource contamination. Our goal is for the reader to understand the complexities of irrigation systems and how they are to be managed to meet the water needs of the crop production system. This is not an irrigation engineering design book; we have purposely minimized the presentation of design steps and the supporting equations. The intended audience of the book is upper-level undergraduate students and graduate students who are pursuing degrees in Agricultural or Natural Resource Sciences. Example majors include Agricultural Systems Technology, Agronomy, Crop Science, Mechanized Systems Management (or equivalent), Natural Resources Management, Soil Science, and Water Science. We expect the reader to have a basic understanding of soils, crops, physics, and the application of algebraic equations. We have also tried to add enough advanced material to challenge graduate students when the book is used in courses that are taught simultaneously at the undergraduate and graduate level. We hope the book will match the needs of students who plan to work in irrigation and related industries, university extension and outreach, private consulting, government service, or production agriculture and that it will continue to serve as a useful reference to them following completion of their formal education

Irrigation Systems Management

Management of irrigation systems should be based on the desired objectives or outcomes consistent with economic, energy, environmental, labor, water, and resource constraints. Goals can vary from maximizing profit, producing a contracted yield, optimizing water resource use, maintaining the quality of produce, or assuring an attractive landscape. Managers cannot achieve these goals without considering the performance of the irrigation system. This chapter discusses the basic characteristics of various irrigation systems, defines terms that quantify performance, describes basic requirements all systems must provide, gives a range of attributes for systems, and discusses how water supply requirements are governed by ET and system characteristics. Detailed characteristics of specific systems are presented in later chapters. The key here is to understand the basic systems and their relative performance

Negative Cooperativity in the Nitrogenase Fe Protein Electron Delivery Cycle

Nitrogenase catalyzes the ATP-dependent reduction of dinitrogen (N2) to two ammonia (NH3) molecules through the participation of its two protein components, the MoFe and Fe proteins. Electron transfer (ET) from the Fe protein to the catalytic MoFe protein involves a series of synchronized events requiring the transient association of one Fe protein with each αβ half of the α2β2 MoFe protein. This process is referred to as the Fe protein cycle and includes binding of two ATP to an Fe protein, association of an Fe protein with the MoFe protein, ET from the Fe protein to the MoFe protein, hydrolysis of the two ATP to two ADP and two Pi for each ET, Pi release, and dissociation of oxidized Fe protein-(ADP)2 from the MoFe protein. Because the MoFe protein tetramer has two separate αβ active units, it participates in two distinct Fe protein cycles. Quantitative kinetic measurements of ET, ATP hydrolysis, and Pi release during the presteady-state phase of electron delivery demonstrate that the two halves of the ternary complex between the MoFe protein and two reduced Fe protein-(ATP)2 do not undergo the Fe protein cycle independently. Instead, the data are globally fit with a two-branch negative-cooperativity kinetic model in which ET in one-half of the complex partially suppresses this process in the other. A possible mechanism for communication between the two halves of the nitrogenase complex is suggested by normal-mode calculations showing correlated and anticorrelated motions between the two halves

Invariance and plasticity in the Drosophila melanogaster metabolomic network in response to temperature

BACKGROUND: Metabolomic responses to extreme thermal stress have recently been investigated in Drosophila melanogaster. However, a network level understanding of metabolomic responses to longer and less drastic temperature changes, which more closely reflect variation in natural ambient temperatures experienced during development and adulthood, is currently lacking. Here we use high-resolution, non-targeted metabolomics to dissect metabolomic changes in D. melanogaster elicited by moderately cool (18°C) or warm (27°C) developmental and adult temperature exposures. RESULTS: We find that temperature at which larvae are reared has a dramatic effect on metabolomic network structure measured in adults. Using network analysis, we are able to identify modules that are highly differentially expressed in response to changing developmental temperature, as well as modules whose correlation structure is strongly preserved across temperature. CONCLUSIONS: Our results suggest that the effect of temperature on the metabolome provides an easily studied and powerful model for understanding the forces that influence invariance and plasticity in biological networks. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12918-014-0139-6) contains supplementary material, which is available to authorized users

Reassessment of the TM 1517 odonto-postcranial assemblage from Kromdraai B, South Africa, and the maturational pattern of Paranthropus robustus

Objectives The Pleistocene taxon Paranthropus robustus was established in 1938 following the discovery at Kromdraai B, South Africa, of the partial cranium TM 1517a and associated mandible TM 1517b. Shortly thereafter, a distal humerus (TM 1517g), a proximal ulna (TM 1517e), and a distal hallucial phalanx (TM 1517k) were collected nearby at the site, and were considered to be associated with the holotype. TM 1517a‐b represents an immature individual; however, no analysis of the potentially associated postcranial elements has investigated the presence of any endostructural remnant of recent epiphyseal closure. This study aims at tentatively detecting such traces in the three postcranial specimens from Kromdraai B. Materials and Methods By using μXCT techniques, we assessed the developmental stage of the TM 1517b's C‐M3 roots and investigated the inner structure of TM 1517g, TM 1517e, and TM 1517k. Results The M2 shows incompletely closed root apices and the M3 a half‐completed root formation stage. The distal humerus was likely completely fused, while the proximal ulna and the distal hallucial phalanx preserve endosteal traces of the diaphyseo‐epiphyseal fusion process. Discussion In the hominin fossil record, there are few unambiguously associated craniodental and postcranial remains sampling immature individuals, an essential condition for assessing the taxon‐specific maturational patterns. Our findings corroborate the original association of the craniodental and postcranial remains representing the P. robustus type specimen. As with other Plio‐Pleistocene hominins, the odonto‐postcranial maturational pattern of TM 1517 more closely fits an African great ape rather than the extant human pattern

Fiscal Centralization, Limited Government, and Public Revenues in Europe, 1650-1913

Old Regime polities typically suffered from fiscal fragmentation and absolutist rule. By the start of World War I, however, many such countries had centralized institutions and limited government. This article uses a new panel data set to perform a statistical analysis of political regimes and public revenues in Europe from 1650 to 1913. Panel regressions indicate that centralized and limited regimes were associated with significantly higher revenues than fragmented and absolutist ones. Structural break tests also suggest close relationships between major turning points in revenue series and political transformations