559 research outputs found

    International Conference on Litigation Funding

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    The aim of the research is to examine the potential for third party litigation funding as a tool to increase access to justice and overcome some of the obstacles faced by some plaintiffs due to the high costs of litigation. The research is empirical in nature and will examine the practical, ethical and regulatory issues relating to third party litigation funding

    Multi-Party Actions: A European Approach

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    Product Liability in Europe: Politics, Reform and Reality

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    Pronounced impairment of activities of daily living in posterior cortical atrophy

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    Introduction : The impact of several dementia syndromes on activities of daily living (ADLs) has been well documented, but no study has yet investigated functional ability in posterior cortical atrophy (PCA). The primarily visual nature of deficits in this condition is likely to have a pronounced impact on ADLs. Objective : The aim of this study was to profile functional change in PCA and identify predictors of change. Method : Twenty-nine PCA patients and 25 patients with typical Alzheimer’s disease (AD) and their caregivers were included in this cross-sectional study. ADLs were assessed using the Disability Assessment for Dementia (DAD), administered to caregivers, assessing basic ADLs (e.g., eating, dressing) and instrumental ADLs (e.g., managing finances, meal preparation). The predictive utility of cognitive domains (Addenbrooke’s Cognitive Examination), behavioural impairment (Cambridge Behavioural Inventory-Revised) and demographic variables on ADL ability was also examined. Results : PCA patients showed significantly reduced total ADL scores compared to AD patients (medium effect size, d = –0.7; p 0.05). A model combining patient mood, disinhibition, apathy, symptom duration, and memory and attention/orientation scores explained the variance of scores in functional decline (61.2%), but the key factor predicting ADL scores was attention/orientation (p = 0.048). Conclusion : This study shows the profound impact of PCA on ADLs and factors underpinning patients’ disability. Attention/orientation deficits were found to correlate and contribute to variance in ADL scores. Future work to develop tailored interventions to manage ADL impairment in PCA should take these findings into account

    Significado paleogeográfico de la presencia de gastrópodos marinos en rocas del Jurásico Temprano (Hettangiano medio) de la Formación Pogibshi, Alaska

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    A middle Hettangian marine gastropod assemblage is reported from the Kenai Peninsula of south-central Alaska supplying new paleontological evidence of this group in Lower Jurassic rocks of North America. Pleurotomaria pogibshiensis sp. nov. is described from the middle Hettangian marine succession informally known as Pogibshi formation, being the first occurrence of the genus in the Kenai Peninsula and the oldest occurrence of the genus in present-day Alaska and North America. One species of the genus Lithotrochus, namely Lithotrochus humboldtii (von Buch), is also reported for the first time from the Kenai Peninsula. Lithotrochus has been considered as endemic to South America for a time range from the early Sinemurian to the late Pliensbachian. The newest occurrence of Lithotrochus in rocks of the Pogibshi formation extends the paleobiogeographical and chronostratigraphical distribution of the genus into the present-day Northern Hemisphere. However, the Southern Hemisphere affinities are consistent with the hypothetical interpretations (although supported both by paleobiogeographical and paleomagnetic data) that the Peninsular terrane of south-central Alaska is far-traveled and may have originated at much more southerly paleolatitudes than its present-day position. Two other Early Jurassic caenogastropods typical of the Andean region of South America and of the Tethyan epicontinental seas are described for the first time in the Pogibshi formation, and these are Pseudomelania sp. and Pictavia sp. The new gastropod assemblage reported here shows close affinities with coeval South American and European gastropod faunas, supplying new evidence to interpret their distribution during the Early Jurassic.Una nueva asociación de gastrópodos del Hettangiano medio reconocida en la región sur central de Alaska, aporta nueva evidencia paleontólogica sobre la presencia de este grupo en el Jurásico Inferior de América del Norte. Pleurotomaria pogibshiensis sp. nov. está presente en depósitos marinos del Hettangiano medio de la unidad informalmente conocida como formación Pogibshi, y es la primera ocurrencia del género en la Península Kenai y el registro más antiguo para Alaska y Norte América. Una especie del género Lithotrochus, Lithotrochus humboldtii (von Buch), también se reporta por primera vez en Alaska. Lithotrochus ha sido considerado hasta el momento un género endémico de América del Sur para un intervalo de tiempo, que se extiende desde el Sinemuriano temprano al Pliensbachiano tardío. El nuevo registro de Lithotrochus en rocas de la Formación Pogibshi permite extender su distribución paleobiogeográfica y cronoestratigráfica en el actual hemisferio Norte. Sin embargo, las afinidades con el hemisferio Sur están en consonancia con la interpretación (apoyada por datos paleobiogeográficos y paleomagnéticos) de que el territorio peninsular del centro-sur de Alaska es alóctono y pudo haberse originado en paleolatitudes mucho más al sur que su posición actual. Otros dos caenogastrópodos típicos de la región andina de América del Sur y de los mares epicontinentales del Tethys, tales como Pseudomelania sp. and Pictavia sp., se describen por primera vez para el Jurásico Inferior de la formación Pogibshi. La nueva asociación de gastrópodos aquí descrita muestra estrechas afinidades con faunas coetáneas de América del Sur y Europa, lo que otorga nuevas evidencias para interpretar sus patrones de distribución paleobiogeográfica durante el Jurásico temprano.Fil: Ferrari, Silvia Mariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Instituto Patagónico de Geología y Paleontología; ArgentinaFil: Blodgett, Robert B.. Blodgett and Associates; Estados UnidosFil: Hodges, Montana S.. California State University Sacramento; Estados UnidosFil: Hodges, Christopher L.. California State University Sacramento; Estados Unido
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