Energy Density of Non-Minimally Coupled Scalar Field Cosmologies

Scalar fields coupled to gravity via $\xi R {\Phi}^2$ in arbitrary Friedmann-Robertson-Walker backgrounds can be represented by an effective flat space field theory. We derive an expression for the scalar energy density where the effective scalar mass becomes an explicit function of $\xi$ and the scale factor. The scalar quartic self-coupling gets shifted and can vanish for a particular choice of $\xi$. Gravitationally induced symmetry breaking and de-stabilization are possible in this theory.Comment: 18 pages in standard Late

Gene Expression Signature in Adipose Tissue of Acromegaly Patients.

To study the effect of chronic excess growth hormone on adipose tissue, we performed RNA sequencing in adipose tissue biopsies from patients with acromegaly (n = 7) or non-functioning pituitary adenomas (n = 11). The patients underwent clinical and metabolic profiling including assessment of HOMA-IR. Explants of adipose tissue were assayed ex vivo for lipolysis and ceramide levels. Patients with acromegaly had higher glucose, higher insulin levels and higher HOMA-IR score. We observed several previously reported transcriptional changes (IGF1, IGFBP3, CISH, SOCS2) that are known to be induced by GH/IGF-1 in liver but are also induced in adipose tissue. We also identified several novel transcriptional changes, some of which may be important for GH/IGF responses (PTPN3 and PTPN4) and the effects of acromegaly on growth and proliferation. Several differentially expressed transcripts may be important in GH/IGF-1-induced metabolic changes. Specifically, induction of LPL, ABHD5, and NRIP1 can contribute to enhanced lipolysis and may explain the elevated adipose tissue lipolysis in acromegalic patients. Higher expression of TCF7L2 and the fatty acid desaturases FADS1, FADS2 and SCD could contribute to insulin resistance. Ceramides were not different between the two groups. In summary, we have identified the acromegaly gene expression signature in human adipose tissue. The significance of altered expression of specific transcripts will enhance our understanding of the metabolic and proliferative changes associated with acromegaly

Can a wormhole supported by only small amounts of exotic matter really be traversable?

Recent studies have shown that (a) quantum effects may be sufficient to support a wormhole throat and (b) the total amount of "exotic matter" can be made arbitrarily small. Unfortunately, using only small amounts of exotic matter may result in a wormhole that flares out too slowly to be traversable in a reasonable length of time. Combined with the Ford-Roman constraints, the wormhole may also come close to having an event horizon at the throat. This paper examines a model that overcomes these difficulties, while satisfying the usual traversability conditions. This model also confirms that the total amount of exotic matter can indeed be made arbitrarily small.Comment: 8 pages, AMSTe

Heat kernel regularization of the effective action for stochastic reaction-diffusion equations

The presence of fluctuations and non-linear interactions can lead to scale dependence in the parameters appearing in stochastic differential equations. Stochastic dynamics can be formulated in terms of functional integrals. In this paper we apply the heat kernel method to study the short distance renormalizability of a stochastic (polynomial) reaction-diffusion equation with real additive noise. We calculate the one-loop {\emph{effective action}} and its ultraviolet scale dependent divergences. We show that for white noise a polynomial reaction-diffusion equation is one-loop {\emph{finite}} in $d=0$ and $d=1$, and is one-loop renormalizable in $d=2$ and $d=3$ space dimensions. We obtain the one-loop renormalization group equations and find they run with scale only in $d=2$.Comment: 21 pages, uses ReV-TeX 3.

On thin-shell wormholes evolving in flat FRW spacetimes

We analize the stability of a class of thin-shell wormholes with spherical symmetry evolving in flat FRW spacetimes. The wormholes considered here are supported at the throat by a perfect fluid with equation of state $\mathcal{P}=w\sigma$ and have a physical radius equal to $aR$, where $a$ is a time-dependent function describing the dynamics of the throat and $R$ is the background scale factor. The study of wormhole stability is done by means of the stability analysis of dynamic systems.Comment: 8 pages; to appear in MPL

Dilatonic wormholes: construction, operation, maintenance and collapse to black holes

The CGHS two-dimensional dilaton gravity model is generalized to include a ghost Klein-Gordon field, i.e. with negative gravitational coupling. This exotic radiation supports the existence of static traversible wormhole solutions, analogous to Morris-Thorne wormholes. Since the field equations are explicitly integrable, concrete examples can be given of various dynamic wormhole processes, as follows. (i) Static wormholes are constructed by irradiating an initially static black hole with the ghost field. (ii) The operation of a wormhole to transport matter or radiation between the two universes is described, including the back-reaction on the wormhole, which is found to exhibit a type of neutral stability. (iii) It is shown how to maintain an operating wormhole in a static state, or return it to its original state, by turning up the ghost field. (iv) If the ghost field is turned off, either instantaneously or gradually, the wormhole collapses into a black hole.Comment: 9 pages, 7 figure

Mirror symmetry breaking as a problem in dynamical critical phenomena

The critical properties of the Frank model of spontaneous chiral synthesis are discussed by applying results from the field theoretic renormalization group (RG). The long time and long wavelength features of this microscopic reaction scheme belong to the same universality class as multi-colored directed percolation processes. Thus, the following RG fixed points (FP) govern the critical dynamics of the Frank model for d<4: one unstable FP that corresponds to complete decoupling between the two enantiomers, a saddle-point that corresponds to symmetric interspecies coupling, and two stable FPs that individually correspond to unidirectional couplings between the two chiral molecules. These latter two FPs are associated with the breakdown of mirror or chiral symmetry. In this simplified model of molecular synthesis, homochirality is a natural consequence of the intrinsic reaction noise in the critical regime, which corresponds to extremely dilute chemical systems.Comment: 9 pages, 3 figure

Renormalization Group Analysis of a Quivering String Model of Posture Control

Scaling concepts and renormalization group (RG) methods are applied to a simple linear model of human posture control consisting of a trembling or quivering string subject to damping and restoring forces. The string is driven by uncorrelated white Gaussian noise intended to model the corrections of the physiological control system. We find that adding a weak quadratic nonlinearity to the posture control model opens up a rich and complicated phase space (representing the dynamics) with various non-trivial fixed points and basins of attraction. The transition from diffusive to saturated regimes of the linear model is understood as a crossover phenomenon, and the robustness of the linear model with respect to weak non-linearities is confirmed. Correlations in posture fluctuations are obtained in both the time and space domain. There is an attractive fixed point identified with falling. The scaling of the correlations in the front-back displacement, which can be measured in the laboratory, is predicted for both the large-separation (along the string) and long-time regimes of posture control.Comment: 20 pages, 13 figures, RevTeX, accepted for publication in PR

On a class of stable, traversable Lorentzian wormholes in classical general relativity

It is known that Lorentzian wormholes must be threaded by matter that violates the null energy condition. We phenomenologically characterize such exotic matter by a general class of microscopic scalar field Lagrangians and formulate the necessary conditions that the existence of Lorentzian wormholes imposes on them. Under rather general assumptions, these conditions turn out to be strongly restrictive. The most simple Lagrangian that satisfies all of them describes a minimally coupled massless scalar field with a reversed sign kinetic term. Exact, non-singular, spherically symmetric solutions of Einstein's equations sourced by such a field indeed describe traversable wormhole geometries. These wormholes are characterized by two parameters: their mass and charge. Among them, the zero mass ones are particularly simple, allowing us to analytically prove their stability under arbitrary space-time dependent perturbations. We extend our arguments to non-zero mass solutions and conclude that at least a non-zero measure set of these solutions is stable.Comment: 23 pages, 4 figures, uses RevTeX4. v2: Changes to accommodate added references. Statement about masses of the wormhole correcte

Positivity of Entropy in the Semi-Classical Theory of Black Holes and Radiation

Quantum stress-energy tensors of fields renormalized on a Schwarzschild background violate the classical energy conditions near the black hole. Nevertheless, the associated equilibrium thermodynamical entropy $\Delta S$ by which such fields augment the usual black hole entropy is found to be positive. More precisely, the derivative of $\Delta S$ with respect to radius, at fixed black hole mass, is found to vanish at the horizon for {\it all} regular renormalized stress-energy quantum tensors. For the cases of conformal scalar fields and U(1) gauge fields, the corresponding second derivative is positive, indicating that $\Delta S$ has a local minimum there. Explicit calculation shows that indeed $\Delta S$ increases monotonically for increasing radius and is positive. (The same conclusions hold for a massless spin 1/2 field, but the accuracy of the stress-energy tensor we employ has not been confirmed, in contrast to the scalar and vector cases). None of these results would hold if the back-reaction of the radiation on the spacetime geometry were ignored; consequently, one must regard $\Delta S$ as arising from both the radiation fields and their effects on the gravitational field. The back-reaction, no matter how "small",Comment: 19 pages, RevTe