Late-1980s regime shift in the formation of the North Pacific subtropical mode water

Author Posting. © American Geophysical Union, 2020. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Journal of Geophysical Research-Oceans 125(2), (2020): e2019JC015700, doi:10.1029/2019JC015700.The formation mechanism as well as its temporal change of the North Pacific subtropical mode water (NPSTMW) is investigated using a 50‐year (1960–2009) ocean general circulation model hindcast. The volume budget analysis suggests that the formation of the NPSTMW is mainly controlled by the air‐sea interaction and ocean dynamics, but there is a regime shift of the relative importance between the two around late‐1980s. While the local air‐sea interaction process is a main driver of the NPSTMW formation prior to late‐1980s, ocean dynamics including the vertical entrainment become dominant since then. The NPSTMW formation is affected by the North Pacific Oscillation simultaneously in the early period, but with a few years lag in the later period. The interdecadal change of the driving mechanism of the interannual variability of the NPSTMW is probably due to the stronger (weaker) influence of local atmospheric forcing in the western North Pacific and unfavorable (favorable) wind stress curl condition for the remote oceanic forcing from the central North Pacific during the former (later) period. This regime shift may be related to the change of centers of the actions of the wind stress curl since the late‐1980s.The CORE2 data set was obtained from https://data1.gfdl.noaa.gov/nomads/forms/core/COREv2.html. The World Ocean Atlas 2009 and the Polar Hydrographic Climatology data set were obtained from https://www.nodc.noaa.gov/OC5/WOA09/pr_woa09.html and http://psc.apl.washington.edu/nonwp_projects/PHC/Climatology.html, respectively. The OSCAR data were taken from https://podaac.jpl.nasa.gov/dataset/OSCAR_L4_OC_third‐deg. The database of mixed layer depth is downloaded from http://mixedlayer.ucsd.edu. The data set of the Argo floats was taken from http://uskess.whoi.edu/. The sea surface height data observed by the satellite are available from AVISO (http://www.aviso.altimetry.fr/duacs/). The EN4 data set was downloaded from https://www.metoffice.gov.uk/hadobs/en4/. This study was supported by the National Research Foundation of Korea (NRF) Grant NRF‐2009‐C1AAA001‐0093, funded by the Korea government (MEST). The numerical simulation in this paper was supported by the Supercomputing Center of Korea Institute of Science and Technology Information (KISTI), with its supercomputing resources and technical support (KSC‐2018‐CRE‐0117). Y.‐O. Kwon was funded by National Science Foundation (NSF) EaSM2 OCE‐1242989. Y. H. Kim was partly supported by research projects entitled “Investigation and prediction system development of marine heatwave around the Korean Peninsula originated from the subarctic and western Pacific” (20190344) funded by the Ministry of Oceans and Fisheries (MOF). G. Pak was supported by in‐house projects of the Korea Institute of Ocean Science & Technology (PE99711, PE99811).2020-09-0

Global efficiency and network structure of urban traffic flows: A percolation-based empirical analysis

Making the connection between the function and structure of networked systems is one of fundamental issues in complex systems and network science. Urban traffic flows are related to various problems in cities and can be represented as a network of local traffic flows. To identify an empirical relation between the function and network structure of urban traffic flows, we construct a time-varying traffic flow network of a megacity, Seoul, and analyze its global efficiency with a percolation-based approach. Comparing the real-world traffic flow network with its corresponding null-model network having a randomized structure, we show that the real-world network is less efficient than its null-model network during rush hour, yet more efficient during non-rush hour. We observe that in the real-world network, links with the highest betweenness tend to have lower quality during rush hour compared to links with lower betweenness, but higher quality during non-rush hour. Since the top betweenness links tend to traverse the entire network, their congestion has a stronger impact on the network's global efficiency. Our results suggest that urban traffic congestion might arise when such backbone links are severely congested rather than the whole system is slowing down.Comment: 7 pages, 4 figure

Platelet-derived growth factor induces p21/WAF1 promoter in vascular smooth muscle cells via activation of an Sp1 site

AbstractMany studies suggested that cyclin-dependent kinase inhibitor (CDKI) p21 acts as a universal inhibitor of cyclin/CDK catalytic activity. This protein has also been shown to be a component of active cyclin/CDK complexes. In addition, it has recently been suggested that p21 serves as an assembly factor in platelet-derived growth factor (PDGF)-stimulated vascular smooth muscle cells (VSMC). However, little is known concerning the molecular mechanisms by which PDGF induces p21 gene expression in VSMC. In this report we demonstrate that PDGF induces the p21 expression at both the mRNA and protein levels. This increase in p21 gene expression was due to activation of the p21 promoter by PDGF. Through both deletion and mutation analysis of the p21 promoter, we defined a 10-bp sequence that is required for the activation of the p21 promoter by PDGF. In addition, gel shift and supershift assays demonstrated that this PDGF-responsive element binds specifically to the transcription factor Sp1. These results demonstrate that Sp1 mediates PDGF-induced p21 gene expression in VSMC. Moreover, immunoblot and immonoprecipitation analysis showed that the level of hyperphosphorylated retinoblastoma protein (Rb) is increased and the protein is physically associated with Sp1 in PDGF-treated cells, indicating that phosphorylated Rb may play a role in regulating Sp1 to activate p21 expression

In vitro embryo rescue for the production of hypotetraploids after cross between hypotetraploid and tetraploid grape cultivars

Consumer demand for seedless grape with high quality and large berry has been increasing. Breeding of hypotetraploid grape was suggested as one of promising methods to satisfy it, but low frequency of hypotetraploid occurrence and low seed germination by abortive embryo were indicated as the major problem to hamper the development of hypotetraploid grape. Hence, this study was carried out to evaluate the basic efficiency of in ovulo embryo culture after the cross between hypotetraploid (‘Hanareum’) and tetraploid (‘Honey Black’ and ‘Kyoho’) grape cultivars on the establishment of hypotetraploid grapes. Embryos and plantlets were hardly obtained in ovules cultured at six after the cross pollination (WAP), but ovules inoculated at 10 WAP produced more embryos as well as plantlets regardless of cross combination. Furthermore, we found that embryo formation was not affected by the basal media in ovules cultured at six WAP, but utilization of specific medium can be more beneficial for embryo formation when ovules were cultured at 10 WAP. A total of 17 plants were obtained from ovules cultured at 10 WAP, and above 50% of plants were identified as hypotetraploid grapes. These results indicate that in vitro embryo rescue after cross pollination between hypotetraploid and tetraploid grape can enhance the efficiency for the breeding of hypotetraploid grapes

Impact of Toxocariasis in Patients with Unexplained Patchy Pulmonary Infiltrate in Korea

Toxocariasis is one of the causes of pulmonary eosinophilic infiltrate that is increasing in Korea. This study was designed to identify the prevalence of toxocara seropositivity in patients with unexplained pulmonary patchy infiltrate and to evaluate associated factors. We evaluated 102 patients with unexplained pulmonary patchy infiltrate on chest computed tomography (CT) scan. As a control set, 116 subjects with normal chest CT were also evaluated. History of allergic disease, drug use, parasitic disease and raw cow liver intake were taken. Blood eosinophil count and total IgE level were measured. Specific serum IgG antibody to Toxocara canis larval antigen and specific IgG antibodies to 4 other parasites were measured by enzyme-linked immunosorbent assay (ELISA). In the infiltrate group, 66.7% subjects were toxocara seropositive whereas 22.4% of the control group were seropositive (p<0.001). In the infiltrate group, patients with a history of eating raw cow liver (odds ratio [OR], 7.8) and patients with eosinophilia (OR, 5.2) had a higher incidence of toxocara seropositivity. Thirty-five percent of toxocara seropositive patients with infiltrate exhibited migrating infiltrate and 48% had decreased infiltrate on the follow-up CT. We recommend that toxocara ELISA should be performed in patients with unexplained pulmonary patchy infiltrate, and that the eating of raw cow liver should be actively discouraged

Climate smart agriculture and global food-crop production

Most business-as-usual scenarios for farming under changing climate regimes project that the agriculture sector will be significantly impacted from increased temperatures and shifting precipitation patterns. Perhaps ironically, agricultural production contributes substantially to the problem with yearly greenhouse gas (GHG) emissions of about 11% of total anthropogenic GHG emissions, not including land use change. It is partly because of this tension that Climate Smart Agriculture (CSA) has attracted interest given its promise to increase agricultural productivity under a changing climate while reducing emissions. Considerable resources have been mobilized to promote CSA globally even though the potential effects of its widespread adoption have not yet been studied. Here we show that a subset of agronomic practices that are often included under the rubric of CSA can contribute to increasing agricultural production under unfavorable climate regimes while contributing to the reduction of GHG. However, for CSA to make a significant impact important investments and coordination are required and its principles must be implemented widely across the entire sector