Growth and structural characterization of molecular superlattice of quaterrylene and N,N′-dioctyl-3,4,9,10-perylenedicarboximide

A molecular superlattice consisting of alternate layers of N,N 0 -dioctyl-3,4,9,10-perylenedi-carboximide (PTCDI-C 8 ) and quaterrylene was prepared by using an ultra-slow depositiontechnique. Film growth under equilibrium conditions with precise optimization of the sub-strate temperature enabled the layer-by-layer stacking of hetero-molecules at a single-layer level. The morphology of the films and the orientation of the molecules in each layerwere analyzed by atomic force microscopy (AFM) and an X-ray reflection (XRR) technique

Structural analysis and transistor properties of hetero-molecular bilayers

We examined the film morphologies and transistor properties of hetero-molecular bilayer consisting of N, N’-dioctyl-3, 4, 9, 10-perylenedicarboximide (PTCDI-C 8 ) and quaterrylene. First, the structure and carrierconduction of PTCDI-C 8 films were studied, followed by an analysis of the carrier accumulation process in aPTCDI-C 8 /quaterrylene hetero-bilayer transistor. Based on the displacement current measurement (DCM),we stress the potential of the hetero-bilayer for tuning carrier accumulation like carrier doping techniques infield-effect transistors

Effects of molsidomine on retinopathy and oxidative stress induced by radiotheraphy in rat eyes

Parlakpinar, Hakan/0000-0001-9497-3468; OZER, MURAT ATABEY/0000-0003-1807-6911WOS: 000400977100023PubMed: 27897441Purpose: To determine the role of Molsidomine in preventing radiation-induced retinopathy after head and neck region irradiation of rats with a single radiation dose of 15 Gy. Materials and Methods: Male Wistar albino rats were randomly grouped into five as follows: (1) control group rats, which were applied through an intraperitoneal (i.p.) vehicle without radiotherapy (RT); (2) RT group rats received a single dose of 15 Gy irradiation and after daily 0.1 ml vehicle i.p. for 5 consecutive days; (3) molsidomine (MOL) group rats were treated for 5 consecutive days by i.p. with 4 mg/kg/day MOL; (4) irradiation plus MOL group (RT+MOL) rats received irradiation and after 10 days single daily i.p. dose of MOL for 5 consecutive days; and (5) MOL+RT group rats were treated for 5 consecutive days by i.p. with MOL before RT. At the end of the work the rats were sacrificed under high-dose anesthesia on the 16(th) day and then eye tissues were taken for histopathological, immunohistochemical (caspase-3), and biochemical analyses (superoxide dismutase [SOD], glutathione peroxidase [GSH], and malondialdehyde [MDA]). Results: RT significantly decreased both the content of GSH and the activity of SOD, and significantly increased the production of MDA level in the rat eyes. MOL treatment significantly increased the SOD and GSH levels and significantly decreased the MDA production (p < 0.0001). In addition, RT significantly increased the number of ganglion cells (GCs; p = 0.001), whereas especially pretreatment with MOL improved (p = 0.013). RT led to significant retinopathy formation, and MOL therapy protected the retina from radiation-induced retinopathy (p < 0.0001). Conclusions: We suggest that MOL is a powerful antioxidant and free radical scavenger that prevents the rat eyes from radiation-induced retinopathy and oxidative stress