5 research outputs found

    COMBINING MODERATE PULSED ELECTRIC FIELDS WITH TEMPERATURE AND WITH ORGANIC ACIDS TO INACTIVATE ESCHERICHIA COLI SUSPENSIONS

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    The aim of this work was to study the efficiency of inactivation of Escherichia coli cells in aqueous suspensions using combined moderate pulsed electric field (PEF) and thermal treatments. The inactivation kinetics of E. coli cells in aqueous suspensions (1 wt%) was monitored using conductometric technique. The electric field strength E was within 5-7.5 kV/cm, the effective PEF treatment time was within 0-0.75 s, the pulse duration ti was within 0.3-1 ms, the medium temperature was 30-50°C, and the time of thermal treatment tT was within 0-7000 s. The organic acid concentration was within 0-0.5 g/L.The damage of E. coli was accompanied by release of intracellular components. The synergy between the PEF and thermal treatments in E. coli inactivation was clearly demonstrated. The damage efficiency was noticeably improved by addition of organic acids, especially lactic acid

    Neuropathie optique au cours de l’encéphalopathie de Gayet-Wernicke

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    L’encéphalopathie de Gayet-Wernicke est une neuropathie rare, secondaire à un déficit en thiamine (Vitamine B1). Elle est essentiellement rencontrée chez les patients alcooliques, chez les patients au décours d’une chirurgie bariatrique ainsi que dans le contexte d’hyperémèse gravidique. Le diagnostic est clinique, il comporte la triade : syndrome confusionnel, troubles oculomoteurs et ataxie. La confirmation du diagnostic repose sur le dosage plasmatique de la vitamine B1 et sur l’IRM cérébrale qui montre des hyper signaux en séquence FLAIR au niveau périaqueducal, thalamique et au niveau ses corps mamillaires. Le pronostic de cette pathologie est mauvais avec une mortalité atteignant 30 % en moyenne. Cependant, le diagnostic précoce et le traitement substitutif urgent permettent la réversibilité de l’atteinte neurologique. Abstract:Gayet-Wernicke encephalopathy is a rare neuropathy caused by a thiamine deficiency (Vitamin B1). Classically, is characterised by the triad: ophtalmoplegia/nystagmus, ataxia and confusion. It is often found in alcoholic patients, gastrectomized patients, but rarely in the context of hyperemesis during pregnancy. The prognosis for this pathology is poor, can lead to blindness, coma or death; in the absence of thiamine supplementation. We report the case of a patient who was 19 weeks of amenorrhea and presented Gayet-Wernicke encephalopathy secondary to pregnancy vomiting.
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