Recurrent rhabdomyolysis caused by carnitine palmitoyltransferase II deficiency, common but under-recognised: Lessons to be learnt

We discuss two adult siblings who presented with symptoms of myalgia and rhabdomyolysis following exercise with myoglobinuria; genetic testing confirmed carnitine palmitoyltransferase II deficiency and resulted in institution of appropriate crisis management and dietary advice. We explore the phenotypic variability of this commonest fatty oxidation defect that remains under-diagnosed in the adult population and provide clues for early recognition and diagnosis

Classification of multipartite entangled states by multidimensional determinants

We find that multidimensional determinants "hyperdeterminants", related to entanglement measures (the so-called concurrence or 3-tangle for the 2 or 3 qubits, respectively), are derived from a duality between entangled states and separable states. By means of the hyperdeterminant and its singularities, the single copy of multipartite pure entangled states is classified into an onion structure of every closed subset, similar to that by the local rank in the bipartite case. This reveals how inequivalent multipartite entangled classes are partially ordered under local actions. In particular, the generic entangled class of the maximal dimension, distinguished as the nonzero hyperdeterminant, does not include the maximally entangled states in Bell's inequalities in general (e.g., in the $n \geq 4$ qubits), contrary to the widely known bipartite or 3-qubit cases. It suggests that not only are they never locally interconvertible with the majority of multipartite entangled states, but they would have no grounds for the canonical n-partite entangled states. Our classification is also useful for the mixed states.Comment: revtex4, 10 pages, 4 eps figures with psfrag; v2 title changed, 1 appendix added, to appear in Phys. Rev.

An Extreme Solar Event of 20 January 2005: Properties of the Flare and the Origin of Energetic Particles

The extreme solar and SEP event of 20 January 2005 is analyzed from two perspectives. Firstly, we study features of the main phase of the flare, when the strongest emissions from microwaves up to 200 MeV gamma-rays were observed. Secondly, we relate our results to a long-standing controversy on the origin of SEPs arriving at Earth, i.e., acceleration in flares, or shocks ahead of CMEs. All emissions from microwaves up to 2.22 MeV line gamma-rays during the main flare phase originated within a compact structure located just above sunspot umbrae. A huge radio burst with a frequency maximum at 30 GHz was observed, indicating the presence of a large number of energetic electrons in strong magnetic fields. Thus, protons and electrons responsible for flare emissions during its main phase were accelerated within the magnetic field of the active region. The leading, impulsive parts of the GLE, and highest-energy gamma-rays identified with pi^0-decay emission, are similar and correspond in time. The origin of the pi^0-decay gamma-rays is argued to be the same as that of lower energy emissions. We estimate the sky-plane speed of the CME to be 2000-2600 km/s, i.e., high, but of the same order as preceding non-GLE-related CMEs from the same active region. Hence, the flare itself rather than the CME appears to determine the extreme nature of this event. We conclude that the acceleration, at least, to sub-relativistic energies, of electrons and protons, responsible for both the flare emissions and the leading spike of SEP/GLE by 07 UT, are likely to have occurred simultaneously within the flare region. We do not rule out a probable contribution from particles accelerated in the CME-driven shock for the leading GLE spike, which seemed to dominate later on.Comment: 34 pages, 14 Postscript figures. Solar Physics, accepted. A typo corrected. The original publication is available at http://www.springerlink.co

Multispecies virial expansions

We study the virial expansion of mixtures of countably many different types of particles. The main tool is the Lagrange–Good inversion formula, which has other applications such as counting coloured trees or studying probability generating functions in multi-type branching processes. We prove that the virial expansion converges absolutely in a domain of small densities. In addition, we establish that the virial coefficients can be expressed in terms of two-connected graphs

An Anglo-Saxon execution cemetery at Walkington Wold, Yorkshire

This paper presents a re-evaluation of a cemetery excavated over 30 years ago at Walkington Wold in east Yorkshire. The cemetery is characterized by careless burial on diverse alignments, and by the fact that most of the skeletons did not have associated crania. The cemetery has been variously described as being the result of an early post-Roman massacre, as providing evidence for a ‘Celtic’ head cult or as an Anglo-Saxon execution cemetery. In order to resolve the matter, radiocarbon dates were acquired and a re-examination of the skeletal remains was undertaken. It was confirmed that the cemetery was an Anglo-Saxon execution cemetery, the only known example from northern England, and the site is set into its wider context in the paper

Exact Minimum Eigenvalue Distribution of an Entangled Random Pure State

A recent conjecture regarding the average of the minimum eigenvalue of the reduced density matrix of a random complex state is proved. In fact, the full distribution of the minimum eigenvalue is derived exactly for both the cases of a random real and a random complex state. Our results are relevant to the entanglement properties of eigenvectors of the orthogonal and unitary ensembles of random matrix theory and quantum chaotic systems. They also provide a rare exactly solvable case for the distribution of the minimum of a set of N {\em strongly correlated} random variables for all values of N (and not just for large N).Comment: 13 pages, 2 figures included; typos corrected; to appear in J. Stat. Phy

Design, testing, and installation of a high-precision hexapod for the Hobby-Eberly Telescope Dark Energy Experiment (HETDEX)

Engineers from The University of Texas at Austin Center for Electromechanics and McDonald Observatory have designed, built, and laboratory tested a high payload capacity, precision hexapod for use on the Hobby-Eberly telescope as part of the HETDEX Wide Field Upgrade (WFU). The hexapod supports the 4200 kg payload which includes the wide field corrector, support structure, and other optical/electronic components. This paper provides a recap of the hexapod actuator mechanical and electrical design including a discussion on the methods used to help determine the actuator travel to prevent the hexapod payload from hitting any adjacent, stationary hardware. The paper describes in detail the tooling and methods used to assemble the full hexapod, including many of the structures and components which are supported on the upper hexapod frame. Additionally, details are provided on the installation of the hexapod onto the new tracker bridge, including design decisions that were made to accommodate the lift capacity of the Hobby-Eberly Telescope dome crane. Laboratory testing results will be presented verifying that the performance goals for the hexapod, including positioning, actuator travel, and speeds have all been achieved. This paper may be of interest to mechanical and electrical engineers responsible for the design and operations of precision hardware on large, ground based telescopes. In summary, the hexapod development cycle from the initial hexapod actuator performance requirements and design, to the deployment and testing on the newly designed HET tracker system is all discussed, including lessons learned through the process.Center for Electromechanic

The first multi-wavelength campaign of AXP 4U 0142+61 from radio to hard X-rays

For the first time a quasi-simultaneous multi-wavelength campaign has been performed on an Anomalous X-ray Pulsar from the radio to the hard X-ray band. 4U 0142+61 was an INTEGRAL target for 1 Ms in July 2005. During these observations it was also observed in the X-ray band with Swift and RXTE, in the optical and NIR with Gemini North and in the radio with the WSRT. In this paper we present the source-energy distribution. The spectral results obtained in the individual wave bands do not connect smoothly; apparently components of different origin contribute to the total spectrum. Remarkable is that the INTEGRAL hard X-ray spectrum (power-law index 0.79 +/- 0.10) is now measured up to an energy of ~230 keV with no indication of a spectral break. Extrapolation of the INTEGRAL power-law spectrum to lower energies passes orders of magnitude underneath the NIR and optical fluxes, as well as the low ~30 microJy (2 sigma) upper limit in the radio band.Comment: 6 pages, 1 figure. To be published in the proceedings of the conference "Isolated Neutron Stars: from the Interior to the Surface" (April 24-28, 2006, London, UK), eds. S. Zane, R. Turolla and D. Pag