Quality of life in adult patients with acne vulgaris before and after treatment

Objectives: To investigate effect of acne treatment on quality of life in patients with acne vulgaris.Materials and methods: The study was prospective and conducted in a university hospital, enrolling the previously untreated patients with acne vulgaris. Before treatment, dermatology life quality index (DLQI) was applied to all participants of both study and control group. After 3rd and 6th months of treatment administration, DLQI tool was applied to patients in the study group, and scores were compared.Results: The acne severity of patients in the study group was 17 (27.9%), 34 (55.7%) and 10 (16.4%) for mild, moderate and severe form, respectively. Mean scoring for DLQI in the study group and the control group was 8.74±5.07 and 2.21±2.44, respectively (p=0.0005). In the study, significant difference were observed in life quality scores between severe acne and mild acne patients, and between severe acne and moderate acne patients (p=0.003 and p=0.011, respectively), but not between mild and moderate acne patients (p=0.937). Effect of gender in acne vulgaris on quality of life was not significantly different (p=0.336). At stage of treatment at the end of 3rd and 6th month, improvements on quality of life was observed significant for overall and all classification of acne severity (mild, moderate and severe; p<0.001, p<0.001 and p<0.001, respectively).Conclusions: We concluded that acne vulgaris was one of the major skin diseases inversely affecting quality of life in patients and we observed that quality of life improved with treatment in patients

Erişkin akne vulgaris hastalarında tedavi öncesi ve sonrası hayat kalitesi

To investigate effect of acne treatment on quality of life in patients with acne vulgaris. Materials and methods: The study was prospective and conducted in a university hospital, enrolling the previously untreated patients with acne vulgaris. Before treatment, dermatology life quality index (DLQI) was applied to all participants of both study and control group. After 3rd and 6th months of treatment administration, DLQI tool was applied to patients in the study group, and scores were compared. Results: The acne severity of patients in the study group was 17 (27.9%), 34 (55.7%) and 10 (16.4%) for mild, moderate and severe form, respectively. Mean scoring for DLQI in the study group and the control group was 8.745.07 and 2.212.44, respectively (p0.0005). In the study, significant difference were observed in life quality scores between severe acne and mild acne patients, and between severe acne and moderate acne patients (p0.003 and p0.011, respectively), but not between mild and moderate acne patients (p0.937). Effect of gender in acne vulgaris on quality of life was not significantly different (p0.336). At stage of treatment at the end of 3rd and 6th month, improvements on quality of life was observed significant for overall and all classification of acne severity (mild, moderate and severe; p0.001, p0.001 and p0.001, respectively). Conclusions: We concluded that acne vulgaris was one of the major skin diseases inversely affecting quality of life in patients and we observed that quality of life improved with treatment in patients.Akne vulgaris hastalarında akne tedavisinin hayat kalitesi üzerine etkisinin incelenmesi amaçlanmıştır. Gereç ve yöntem: çalışma prospektif olarak tasarlandı. Daha öncesinde akne tedavisi almayan hastalar alındı ve çalışma bir üniversite hastanesinde yürütüldü. çalışma grubu ve kontrol grubu oluşturuldu. Tedavi öncesi hastalara ve kontrol grubuna Dermatolojik Yaşam Kalitesi İndeksi (DYKI) ölçeği uygulandı. Tedavi sonrası 3. ve 6. aylarda DYKI tekrar uygulandı. Tüm Skorlar karşılaştırıldı. Bulgular: çalışma grubunda bulunan akne olgularından 17 (%27,9) hasta hafif, 34 hasta orta (%55,7) ve 10 hasta (%16,4) ileri derece akne grubunda idi. çalışma grubu ve kontrol grubunun ortalama DYKI skoru sırası ile 8,74±5,07 ve 2,21±2,44 idi (p0,0005). çalışma grubunda ileri derece akne ile orta derece akne; ileri derece akne ile hafif dereceli akne arasında yaşam kalitesi skoru arasında anlamlı fark izlendi (p0,003, p0,011 sırası ile), fakat hafif ve orta derece akne arasında fark izlenmedi (p0,036). Cinsiyetin akne vulgarisin hastalarında yaşam kalitesi üzerine etkisi izlenmedi (p0,336). Tedavinin 3. ve 6. aylarında çalışma grubunda yaşam kalitesi tüm olgu ve her bir akne derecesi (hafif, orta ve ileri derece) için tekrar değerlendirildi (sırası ile; p<0,001, p<0,001, p<0,001 ve p<0,001). Sonuç: Sonuç olarak, çalışmamızda akne vulgarisin yaşam kalitesini ciddi anlamda etkileyen bir majör deri hastalıklarından biri olduğu, fakat tedavi ile yaşam kalitesinin düzeldiği sonucuna ulaştık

Nevus lipomatosus cutaneous superficialis: Case report

Nevüs lipomatöz superfisiyalis (NLS) üst dermiste ektopic adipositle karakterize seyrek bir deri malformasyonudur. Özellikle lezyonlar gövdenin alt kısmında ve kalçada lokalize olurlar. Zosteri form ve lineer özelliktedir. Buradaki olgu birinci basamakta nadir görülen bir hastalık olması nedeniyle rapor edildi. Vakamızda, 42 yaşında kadın hasta beş yıldır sırt bölgesinde sayıları giderek artan ağrısız ve kaşıntısız kabarık lezyonlarla polikliniğimize başvurdu. Hastanın muayenesinde; sağ skapular bölge alt kısmında zosteri form yerleşim gösteren çok sayıda papülo-nodüller saptandı. Histopatolojik inceleme sonucunda hastamıza NLS tanısı konuldu. NLS’li hastalarda başlıca tedavi seçeneği, benign lezyon olması nedeni ile kozmetik amaçlı yapılan cerrahi eksizyondur. Bu hastada da hastanın lezyonları eksize edildi.Nevus lipomatosus cutaneous superficialis (NLS) is a rare skin malformation characterized by ectopic adipocyte in upper dermis. It is composed of multiple nodular and papular lesions localized especially on lower part of trunk and gluteal region. These lesions have linear and zoster form pattern. In our case, 42 years-old woman admitted to our clinic, presenting with non-painful and non-itchy bulky lesion gradually increased on her upper back region since 5 years. On her examination, multiple nodulo-papular lesions with zoster form pattern localized on lower margin of right scapular region were detected. It was diagnosed as NLS, depending on histopathological investigation. Treatment for NLS is cosmetically surgical excision, and the patient&#8217;s lesion was excised, because it is benign lesion

Naproxen-induced fixed drug eruption: A case report

KARA, ISMAIL HAMDI/0000-0003-2022-1882; KARA, ISMAIL HAMDI/0000-0003-2022-1882WOS: 000296157700016PubMed: 21357631Naproxen is a non-steroidal anti-inflammatory drug (NSAID) widely used for symptomatic relief of arthritis and other painful disorders, such as dysmenorrheal. Pruritus is the most common side effect of naproxen. Fixed drug eruption (FDE) due to naproxen is a rarely reported side-effect. No previous report has declared cross-reactivity between naproxen and other propionic acid derivatives. A 28-year-old man, presented with edematous and erythematous patchy lesion along with pruritus and inflammation on lip, have been suffering since 3 hours. It started after taking naproxen 550 mg for headache. On detailed inquiry, he defined similar symptom which recurred after whenever he took naproxen. Based on clinical and histopathological findings, it is evaluated as naproxen-induced FDE. We have tested cross-reactivity between naproxen and other propionic acid derivatives, and then we obtained negative result for oral provocation test with flurbiprofen. Here, we present a case of naproxen-induced FDE of 28-year-old man, by overviewing literatures

Fiksni medikamentozni eksantem, ki ga izzove ornidazol: Prikaz primera

Fixed Drug Eruption (FDE) is characterized with skin lesions in the instant of ofending drug. It recurs at the same site of the skin or mucous membrane. In our case, 26-year-old female patient was admitted to our emergency department with distinctive and itchy skin lesions afer ornidazole administration. Physical examination revealed erythematous, hyperpigmented and desquamate, non-bullous and well-defned plaque lesions. She had similar medical history with ornidazole use. Histopathological examination with biopsy was performed. Te patient's skin lesions and irritation symptoms have gradually improved with discontinuation of ornidazole, and administering topical and systematic anti-histaminic and steroid therapy. In conclusion, the physician should perform a detailed enquiry for patient's anamnesis. Te offending drug should be discontinued And the patient should be informed about the ofending drug

Ornidazole-induced fixed drug eruption: A case report

KARA, ISMAIL HAMDI/0000-0003-2022-1882; Saritas, Ayhan/0000-0002-4302-1093; KARA, ISMAIL HAMDI/0000-0003-2022-1882; Kandis, Hayati/0000-0001-9151-6050WOS: 000303232000009Fixed Drug Eruption (FDE) is characterized with skin lesions in the instant of offending drug. It recurs at the same site of the skin or mucous membrane. In our case, 26-year-old female patient was admitted to our emergency department with distinctive and itchy skin lesions after ornidazole administration. Physical examination revealed erythematous, hyperpigmented and desquamate, non-bullous and well-defined plaque lesions. She had similar medical history with ornidazole use. Histopathological examination with biopsy was performed. The patient's skin lesions and irritation symptoms have gradually improved with discontinuation of ornidazole, and administering topical and systematic anti-histaminic and steroid therapy. In conclusion, the physician should perform a detailed enquiry for patient's anamnesis. The offending drug should be discontinued And the patient should be informed about the offending drug