Pressure to order g8∗log(g)g^8*log(g) in ϕ4\phi^4-theory at weak coupling

We calculate the pressure of massless $\phi^4$-theory to order $g^8\log(g)$ at weak coupling. The contributions to the pressure arise from the hard momentum scale of order $T$ and the soft momentum scale of order $gT$. Effective field theory methods and dimensional reduction are used to separate the contributions from the two momentum scales: The hard contribution can be calculated as a power series in $g^2$ using naive perturbation theory with bare propagators. The soft contribution can be calculated using an effective theory in three dimensions, whose coefficients are power series in $g^2$. This contribution is a power series in $g$ starting at order $g^3$. The calculation of the hard part to order $g^6$ involves a complicated four-loop sum-integral that was recently calculated by Gynther, Laine, Schr\"oder, Torrero, and Vuorinen. The calculation of the soft part requires calculating the mass parameter in the effective theory to order $g^6$ and the evaluation of five-loop vacuum diagrams in three dimensions. This gives the free energy correct up to order $g^7$. The coefficients of the effective theory satisfy a set of renormalization group equations that can be used to sum up leading and subleading logarithms of $T/gT$. We use the solutions to these equations to obtain a result for the free energy which is correct to order $g^8\log(g)$. Finally, we investigate the convergence of the perturbative series.Comment: 29 pages and 12 figs. New version: we have pushed the calculations to g^8*log(g) using the renormalization group to sum up log(g) from higher orders. Published in JHE

Constraints on Conformal Windows from Holographic Duals

We analyze a beta function with the analytic form of Novikov-Shifman-Vainshtein-Zakharov result in the five dimensional gravity-dilaton environment. We show how dilaton inherits poles and fixed points of such beta function through the zeros and points of extremum in its potential. Super Yang-Mills and supersymmetric QCD are studied in detail and Seiberg's electric-magnetic duality in the dilaton potential is explicitly demonstrated. Non-supersymmetric proposals of similar functional form are tested and new insights into the conformal window as well as determinations of scheme-independent value of the anomalous dimension at the fixed point are presented.Comment: Fig. 5b is corrected to match the discussion in the tex

Differential Cognitive Functioning and Benefit From Surgery in Patients Undergoing Coronary Artery Bypass Grafting and Carotid Endarterectomy

BackgroundStenosing atherosclerosis in both coronary and carotid arteries can adversely affect cognition. Also their surgical treatments, coronary artery bypass grafting (CABG) and carotid endarterectomy (CEA), are associated with cognitive changes, but the mechanisms of cognitive decline or improvement may not be the same. This study was designed to compare the cognitive profile and outcome in patients undergoing surgical treatment for coronary or carotid disease. MethodsA total of 100 CABG patients and 44 CEA patients were recruited in two previously reported studies. They were subjected to a comprehensive neuropsychological examination prior to surgery and in the acute (3-8 days) and stable (3 months) phase after operation. A group of 17 matched healthy controls were assessed with similar intervals. We used linear mixed models to compare cognitive trajectories within six functional domains between the CABG, CEA and control groups. Postoperative cognitive dysfunction (POCD) and improvement (POCI) were determined with the reliable change index method in comparison with healthy controls. ResultsBefore surgery, the CEA patients performed worse than CABG patients or healthy controls in the domains of executive functioning and processing speed. The CABG patients exhibited postoperative cognitive dysfunction more often than the CEA patients in most cognitive domains in the acute phase but had regained their performance in the stable phase. The CEA patients showed more marked postoperative improvement in executive functioning than the CABG group in the acute phase, but the difference did not reach significance in the stable phase. ConclusionOur findings suggest that anterior cerebral dysfunction in CEA patients impairs preoperative cognition more severely than global brain dysfunction in CABG patients. However, CEA may have more beneficial effects on cognition than CABG, specifically in executive functions mainly operated by the prefrontal lobes. In addition, the results underline that POCD is a heterogeneous condition and dependent on type of revascularization surgery.Peer reviewe

Technicolor and Beyond: Unification in Theory Space

The salient features of models of dynamical electroweak symmetry breaking are reviewed. The ideal walking idea is introduced according to which one should carefully take into account the effects of the extended technicolor dynamics on the technicolor dynamics itself. The effects amount at the enhancement of the anomalous dimension of the mass of the techniquarks allowing to decouple the Flavor Changing Neutral Currents problem from the one of the generation of the top mass. Precision data constraints are reviewed focussing on the latest crucial observation that the S-parameter can be computed exactly near the upper end of the conformal window (Conformal S-parameter) with relevant consequences on the selection of nature's next strong force. We will then introduce the Minimal Walking Technicolor (MWT) models. In the second part of this review we consider the interesting possibility to marry supersymmetry and technicolor. The reason is to provide a unification of different extensions of the standard model. For example, this means that one can recover, according to the parameters and spectrum of the theory distinct extensions of the standard model, from supersymmetry to technicolor and unparticle physiscs. A surprising result is that a minimal (in terms of the smallest number of fields) supersymmetrization of the MWT model leads to the maximal supersymmetry in four dimensions, i.e. N=4 SYM.Comment: Extended version of the PASCOS10 proceedings for the Plenary Tal

Large N and Bosonization in Three Dimensions

Bosonization is normally thought of as a purely two-dimensional phenomenon, and generic field theories with fermions in D>2 are not expected be describable by local bosonic actions, except in some special cases. We point out that 3D SU(N) gauge theories on R^{1,1} x S^{1}_{L} with adjoint fermions can be bosonized in the large N limit. The key feature of such theories is that they enjoy large N volume independence for arbitrary circle size L. A consequence of this is a large N equivalence between these 3D gauge theories and certain 2D gauge theories, which matches a set of correlation functions in the 3D theories to corresponding observables in the 2D theories. As an example, we focus on a 3D SU(N) gauge theory with one flavor of adjoint Majorana fermions and derive the large-N equivalent 2D gauge theory. The extra dimension is encoded in the color degrees of freedom of the 2D theory. We then apply the technique of non-Abelian bosonization to the 2D theory to obtain an equivalent local theory written purely in terms of bosonic variables. Hence the bosonized version of the large N three-dimensional theory turns out to live in two dimensions.Comment: 30 pages, 2 tables. v2 minor revisions, references adde

qSNE: quadratic rate t-SNE optimizer with automatic parameter tuning for large datasets

Motivation: Non-parametric dimensionality reduction techniques, such as t-distributed stochastic neighbor embedding (t-SNE), are the most frequently used methods in the exploratory analysis of single-cell datasets. Current implementations scale poorly to massive datasets and often require downsampling or interpolative approximations, which can leave less-frequent populations undiscovered and much information unexploited.Results: We implemented a fast t-SNE package, qSNE, which uses a quasi-Newton optimizer, allowing quadratic convergence rate and automatic perplexity (level of detail) optimizer. Our results show that these improvements make qSNE significantly faster than regular t-SNE packages and enables full analysis of large datasets, such as mass cytometry data, without downsampling.</p

Real-time static potential in hot QCD

We derive a static potential for a heavy quark-antiquark pair propagating in Minkowski time at finite temperature, by defining a suitable gauge-invariant Green's function and computing it to first non-trivial order in Hard Thermal Loop resummed perturbation theory. The resulting Debye-screened potential could be used in models that attempt to describe the ``melting'' of heavy quarkonium at high temperatures. We show, in particular, that the potential develops an imaginary part, implying that thermal effects generate a finite width for the quarkonium peak in the dilepton production rate. For quarkonium with a very heavy constituent mass M, the width can be ignored for T \lsim g^2 M/12\pi, where g^2 is the strong gauge coupling; for a physical case like bottomonium, it could become important at temperatures as low as 250 MeV. Finally, we point out that the physics related to the finite width originates from the Landau-damping of low-frequency gauge fields, and could be studied non-perturbatively by making use of the classical approximation.Comment: 20 pages. v2: a number of clarifications and a few references added; published versio

Differential Cognitive Functioning and Benefit From Surgery in Patients Undergoing Coronary Artery Bypass Grafting and Carotid Endarterectomy

BackgroundStenosing atherosclerosis in both coronary and carotid arteries can adversely affect cognition. Also their surgical treatments, coronary artery bypass grafting (CABG) and carotid endarterectomy (CEA), are associated with cognitive changes, but the mechanisms of cognitive decline or improvement may not be the same. This study was designed to compare the cognitive profile and outcome in patients undergoing surgical treatment for coronary or carotid disease. MethodsA total of 100 CABG patients and 44 CEA patients were recruited in two previously reported studies. They were subjected to a comprehensive neuropsychological examination prior to surgery and in the acute (3-8 days) and stable (3 months) phase after operation. A group of 17 matched healthy controls were assessed with similar intervals. We used linear mixed models to compare cognitive trajectories within six functional domains between the CABG, CEA and control groups. Postoperative cognitive dysfunction (POCD) and improvement (POCI) were determined with the reliable change index method in comparison with healthy controls. ResultsBefore surgery, the CEA patients performed worse than CABG patients or healthy controls in the domains of executive functioning and processing speed. The CABG patients exhibited postoperative cognitive dysfunction more often than the CEA patients in most cognitive domains in the acute phase but had regained their performance in the stable phase. The CEA patients showed more marked postoperative improvement in executive functioning than the CABG group in the acute phase, but the difference did not reach significance in the stable phase. ConclusionOur findings suggest that anterior cerebral dysfunction in CEA patients impairs preoperative cognition more severely than global brain dysfunction in CABG patients. However, CEA may have more beneficial effects on cognition than CABG, specifically in executive functions mainly operated by the prefrontal lobes. In addition, the results underline that POCD is a heterogeneous condition and dependent on type of revascularization surgery.</p

Extreme Technicolor & The Walking Critical Temperature

We map the phase diagram of gauge theories of fundamental interactions in the flavor-temperature plane using chiral perturbation theory to estimate the relation between the pion decaying constant and the critical temperature above which chiral symmetry is restored. We then investigate the impact of our results on models of dynamical electroweak symmetry breaking and therefore on the electroweak early universe phase transition.Comment: RevTeX, 18 pages, 3 figure

Agile Workflow For Interactive Analysis Of Mass Cytometry Data

Motivation: Single-cell proteomics technologies, such as mass cytometry, have enabled characterization of cell-to-cell variation and cell populations at a single cell resolution. These large amounts of data, require dedicated, interactive tools for translating the data into knowledge.Results: We present a comprehensive, interactive method called Cyto to streamline analysis of large-scale cytometry data. Cyto is a workflow-based open-source solution that automates the use of state-of-the-art single-cell analysis methods with interactive visualization. We show the utility of Cyto by applying it to mass cytometry data from peripheral blood and high-grade serous ovarian cancer (HGSOC) samples. Our results show that Cyto is able to reliably capture the immune cell sub-populations from peripheral blood as well as cellular compositions of unique immune- and cancer cell subpopulations in HGSOC tumor and ascites samples.Availability: The method is available as a Docker container at https://hub.docker.com/r/anduril/cyto and the user guide and source code are available at https://bitbucket.org/anduril-dev/cyto.</p