276 research outputs found

    Doing banlieue: politische, mediale und literarische Konstruktionen und Dekonstruktionen des Vorstadtdiskurses im Gegenwartsfrankreich

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    Wenn in Frankreich in Medien und Politik von den banlieues die Rede ist, wird nicht selten ein ‚parallelgesellschaftliches‘ Horrorszenario gezeichnet, das die ‚Mehrheitsgesellschaft‘ vermeintlich bedroht. Der Artikel profiliert die historische Genese und die gesellschaftlichen Machtinteressen, die diesen Diskurs motivieren, und interpretiert vor diesem Hintergrund Abd Al-Maliks La guerre des banlieues n’aura pas lieu (2009) als dekonstruktive Auseinandersetzung mit Stereotypen und Vorurteilen und als Versuch, über eine Ästhetik der Pluralität und Offenheit dem Ab- und Ausgrenzungsdiskurs eine auf Dialog ausgelegte Alternative entgegenzustellen.</p

    Zwischen Text und Leser Wege zur Zukunft der Kognitiven Literaturwissenschaft

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    Sophia Wege: Wahrnehmung, Wiederholung, Vertikalität. Zur Theorie und Praxis der Kognitiven Literaturwissenschaft. Bielefeld: Aisthesis 2013. 532 S. EUR (D) 48,- ISBN 978-3-89528-953-

    Bundles of Interacting Strings in Two Dimensions

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    Bundles of strings which interact via short-ranged pair potentials are studied in two dimensions. The corresponding transfer matrix problem is solved analytically for arbitrary string number N by Bethe ansatz methods. Bundles consisting of N identical strings exhibit a unique unbinding transition. If the string bundle interacts with a hard wall, the bundle may unbind from the wall via a unique transition or a sequence of N successive transitions. In all cases, the critical exponents are independent of N and the density profile of the strings exhibits a scaling form that approaches a mean-field profile in the limit of large N.Comment: 8 pages (latex) with two figure

    Das Leben der Anderen: historische, soziologische und narrative Dimensionen paralleler Sozialität

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    Einleitung der Herausgeber zum Beiheft Parallelgesellschafte

    Fluctuation Pressure of a Stack of Membranes

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    We calculate the universal pressure constants of a stack of N membranes between walls by strong-coupling theory. The results are in very good agreement with values from Monte-Carlo simulations.Comment: Author Information under http://www.physik.fu-berlin.de/~kleinert/institution.html Latest update of paper also at http://www.physik.fu-berlin.de/~kleinert/31

    Theoretical model for the formation of caveolae and similar membrane invaginations

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    We study a physical model for the formation of bud-like invaginations on fluid lipid membranes under tension, and apply this model to caveolae formation. We demonstrate that budding can be driven by membrane-bound proteins, provided that they exert asymmetric forces on the membrane that give rise to bending moments. In particular, caveolae formation does not necessarily require forces to be applied by the cytoskeleton. Our theoretical model is able to explain several features observed experimentally in caveolae, where proteins in the caveolin family are known to play a crucial role in the formation of caveolae buds. These include 1), the formation of caveolae buds with sizes in the 100-nm range and 2), that certain N- and C-termini deletion mutants result in vesicles that are an order-of-magnitude larger. Finally, we discuss the possible origin of the morphological striations that are observed on the surfaces of the caveolae

    Reliability of species detection in 16S microbiome analysis: Comparison of five widely used pipelines and recommendations for a more standardized approach

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    The use of NGS-based testing of the bacterial microbiota is often impeded by inconsistent or non-reproducible results, especially when applying different analysis pipelines and reference databases. We investigated five frequently used software packages by submitting the same monobacterial datasets to them, representing the V1-2 and the V3-4 regions of the 16S-rRNA gene of 26 well characterized strains, which were sequenced by the Ion Torrent™ GeneStudio S5 system. The results obtained were divergent and calculations of relative abundance did not yield the expected 100%. We investigated these inconsistencies and were able to attribute them to failures either of the pipelines themselves or of the reference databases they rely on. On the basis of these findings, we recommend certain standards which should help to render microbiome testing more consistent and reproducible, and thus useful in clinical practice

    Coiling Instability of Multilamellar Membrane Tubes with Anchored Polymers

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    We study experimentally a coiling instability of cylindrical multilamellar stacks of phospholipid membranes, induced by polymers with hydrophobic anchors grafted along their hydrophilic backbone. Our system is unique in that coils form in the absence of both twist and adhesion. We interpret our experimental results in terms of a model in which local membrane curvature and polymer concentration are coupled. The model predicts the occurrence of maximally tight coils above a threshold polymer occupancy. A proper comparison between the model and experiment involved imaging of projections from simulated coiled tubes with maximal curvature and complicated torsions.Comment: 11 pages + 7 GIF figures + 10 JPEG figure

    Contribution of Symptomatic, Herbal Treatment Options to Antibiotic Stewardship and Microbiotic Health

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    Epithelial surfaces in humans are home to symbiotic microbes (i.e., microbiota) that influence the defensive function against pathogens, depending on the health of the microbiota. Healthy microbiota contribute to the well-being of their host, in general (e.g., via the gut–brain axis), and their respective anatomical site, in particular (e.g., oral, urogenital, skin, or respiratory microbiota). Despite efforts towards a more responsible use of antibiotics, they are often prescribed for uncomplicated, self-limiting infections and can have a substantial negative impact on the gut microbiota. Treatment alternatives, such as non-steroidal anti-inflammatory drugs, may also influence the microbiota; thus, they can have lasting adverse effects. Herbal drugs offer a generally safe treatment option for uncomplicated infections of the urinary or respiratory tract. Additionally, their microbiota preserving properties allow for a more appropriate therapy of uncomplicated infections, without contributing to an increase in antibiotic resistance or disturbing the gut microbiota. Here, herbal treatments may be a more appropriate therapy, with a generally favorable safety profile

    Fluctuation spectrum of fluid membranes coupled to an elastic meshwork: jump of the effective surface tension at the mesh size

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    We identify a class of composite membranes: fluid bilayers coupled to an elastic meshwork, that are such that the meshwork's energy is a function Fel[Aξ]F_\mathrm{el}[A_\xi] \textit{not} of the real microscopic membrane area AA, but of a \textit{smoothed} membrane's area AξA_\xi, which corresponds to the area of the membrane coarse-grained at the mesh size ξ\xi. We show that the meshwork modifies the membrane tension σ\sigma both below and above the scale ξ\xi, inducing a tension-jump Δσ=dFel/dAξ\Delta\sigma=dF_\mathrm{el}/dA_\xi. The predictions of our model account for the fluctuation spectrum of red blood cells membranes coupled to their cytoskeleton. Our results indicate that the cytoskeleton might be under extensional stress, which would provide a means to regulate available membrane area. We also predict an observable tension jump for membranes decorated with polymer "brushes"
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