SISTEM PENDUKUNG KEPUTUSAN PEMILIHAN MAHASISWA BERPRESTASI BERBASIS WEB DENGAN METODE FUZZY QUERY

Student Selection and determination to achieve a long and complicated process. The selection process is to have many opportunities to make wrong decisions because the process of selecting students based on subjectivity. This means most likely that the best students are chosen does not achieve the desired standard and not getting the best candidates. Therefore made a decision support system that can perform the calculation on all the criteria for selection of student achievement in accordance with real data. This final project will implement the fuzzy logic into the query, called the Fuzzy Database Query. That is, a query that has a variable-valued fuzzy variables. The problems will be resolved is the selection process on academic merit. Fuzzy method used is the Mamdani fuzzy query model. Students who will be recommended to student achievement has a valuable criteria fuzzy or non-fuzzy value. Fuzzy criteria required GPA among others, training, intra-extracurricular activity, Essay. While non-fuzzy data needed among other majors and years of data. Results from this system in the form of a list of student achievement consistent with real data on academic merit Electronic Engineering Polytechnic Institute Surabaya. The final project is built using the MySQL database and PHP programming language. Key Word : Logika Fuzzy, Himpunan Fuzzy, Fuzzy Query Database, Student achievement

Efekvitas Pembelajaran Praktikum Berbasis Inkuiri Terbimbing terhadap Gerak Adaptif (Keterampilan) Mata Pelajaran Fisika

Tujuan penelitian ini adalah untuk mengetahui gambaran gerak adaptif (keterampilan)peserta didik mata pelajaran fisika sebelum dan setelah penerapan model pembelajaraninkuiri terbimbing kelas VII SMP Negeri 1 KAHU. Pemilihan sampel melalui teknik purposivesampling. Instrumen pengumpulan data untuk meningkatkan gerak adaptif (keterampilan)peserta didik pada mata pelajaran fisika melalui lembar observasi jenis partisipan dandokumentasi. Teknik analisis data menggunakan analisis deskriptif dan inferensial yaitu tsatusampel. Berdasarkan hasil analisis data dengan menggunakan statistik deskriptifdiperoleh nilai rata-rata gerak adaptif (keterampilan) peserta didik sebelum penerapan modelpembelajaran inkuiri terbimbing berada pada kategori cukup, sedangkan nilai rata-ratagerak adaptif (keterampilan) peserta didik setelah penerapan model pembelajaran inkuiriterbimbing berada pada kategori sangat baik. Hasil analisis data inferensial yaitu thitung<ttabelsehingga terdapat perbedaan yang signifikan dalam meningkatkan gerak adaptif(keterampilan) peserta didik dengan penerapan model pembelajaran inkuiri terbimbing padamata pelajaran fisik

Dissolving microarray patches for transdermal delivery of risperidone for schizophrenia management

Schizophrenia is a psychiatric disorder that results from abnormal levels of neurotransmitters in the brain. Risperidone (RIS) is a common drug prescribed for the treatment of schizophrenia. RIS is a hydrophobic drug that is typically administered orally or intramuscularly. Transdermal drug delivery (TDD) could potentially improve the delivery of RIS. This study focused on the development of RIS nanocrystals (NCs), for the first time, which were incorporated into dissolving microneedle array patches (DMAPs) to facilitate the drug delivery of RIS. RIS NCs were formulated via wet-media milling technique using poly(vinylalcohol) (PVA) as a stabiliser. NCs with particle size of 300 nm were produced and showed an enhanced release profile up to 80 % over 28 days. Ex vivo results showed that 1.16 ± 0.04 mg of RIS was delivered to both the receiver compartment and full-thickness skin from NCs loaded DMAPs compared to 0.75 ± 0.07 mg from bulk RIS DMAPs. In an in vivo study conducted using female Sprague Dawley rats, both RIS and its active metabolite 9-hydroxyrisperidone (9-OH-RIS) were detected in plasma samples for 5 days. In comparison with the oral group, DMAPs improved the overall pharmacokinetic profile in plasma with a ∼ 15 folds higher area under the curve (AUC) value. This work has represented the novel delivery of the antipsychotic drug, RIS, through microneedles. It also offers substantial evidence to support the broader application of MAPs for the transdermal delivery of poorly water-soluble drugs

Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

BackgroundDisorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment following COVID-19. Previous publications from the Global Burden of Disease, Injuries, and Risk Factor Study estimated the burden of 15 neurological conditions in 2015 and 2016, but these analyses did not include neurodevelopmental disorders, as defined by the International Classification of Diseases (ICD)-11, or a subset of cases of congenital, neonatal, and infectious conditions that cause neurological damage. Here, we estimate nervous system health loss caused by 37 unique conditions and their associated risk factors globally, regionally, and nationally from 1990 to 2021.MethodsWe estimated mortality, prevalence, years lived with disability (YLDs), years of life lost (YLLs), and disability-adjusted life-years (DALYs), with corresponding 95% uncertainty intervals (UIs), by age and sex in 204 countries and territories, from 1990 to 2021. We included morbidity and deaths due to neurological conditions, for which health loss is directly due to damage to the CNS or peripheral nervous system. We also isolated neurological health loss from conditions for which nervous system morbidity is a consequence, but not the primary feature, including a subset of congenital conditions (ie, chromosomal anomalies and congenital birth defects), neonatal conditions (ie, jaundice, preterm birth, and sepsis), infectious diseases (ie, COVID-19, cystic echinococcosis, malaria, syphilis, and Zika virus disease), and diabetic neuropathy. By conducting a sequela-level analysis of the health outcomes for these conditions, only cases where nervous system damage occurred were included, and YLDs were recalculated to isolate the non-fatal burden directly attributable to nervous system health loss. A comorbidity correction was used to calculate total prevalence of all conditions that affect the nervous system combined.FindingsGlobally, the 37 conditions affecting the nervous system were collectively ranked as the leading group cause of DALYs in 2021 (443 million, 95% UI 378–521), affecting 3·40 billion (3·20–3·62) individuals (43·1%, 40·5–45·9 of the global population); global DALY counts attributed to these conditions increased by 18·2% (8·7–26·7) between 1990 and 2021. Age-standardised rates of deaths per 100 000 people attributed to these conditions decreased from 1990 to 2021 by 33·6% (27·6–38·8), and age-standardised rates of DALYs attributed to these conditions decreased by 27·0% (21·5–32·4). Age-standardised prevalence was almost stable, with a change of 1·5% (0·7–2·4). The ten conditions with the highest age-standardised DALYs in 2021 were stroke, neonatal encephalopathy, migraine, Alzheimer's disease and other dementias, diabetic neuropathy, meningitis, epilepsy, neurological complications due to preterm birth, autism spectrum disorder, and nervous system cancer.InterpretationAs the leading cause of overall disease burden in the world, with increasing global DALY counts, effective prevention, treatment, and rehabilitation strategies for disorders affecting the nervous system are needed

Peran Usaha Kesehatan Sekolah (Uks) sebagai Proses Prilaku Hidup Bersih dan Sehat Peserta Didik

Pelaksanaan Usaha Kesehatan Sekolah merupakan ujung tombak pemberdayaan dilingkungan sekolah agar berperilaku hidup bersih dan sehat.&nbsp;Usaha Kesehatan Sekolah dapat meningkatkan derajat kesehatan serta membentuk prilaku hidup bersih dan sehat peserta didik meliputi: pendidikan kesehatan, pelayanan kesehatan dan pembinaan lingkungan sekolah sehat sebagai langkah untuk meningkatkan mutu kesehatan peserta didik yang optimal.&nbsp;Tujuan UKS adalah meningkatkan mutu pendidikan dan prestasi belajar peserta didik melalui peningkatan perilaku hidup bersih jasmani dan rohani sehingga anak didik dapat tumbuh berkembang secara harmonis dan optimal seiring dengan kemandirian dalam berktifitas dan pada akhirnya menjadi manusia yang berkualitas. Keberhasilan pembinaan dan pengembangan Usaha Kesehatan Sekolah (UKS) akan terlihat atau tercermin pada perilaku hidup bersih dan sehat peserta didik, dan ini merupakan dampak yang diharapkan dari keseluruhan pola pembinaan dan pengembangan UKS. Tujuan dari artikel ini mengenai peran Usaha Kesehatan Sekolah (UKS) sebagai proses Perilaku Hidup Sehat dan Bersih peserta didik

Identifikasi Pemahaman Siswa Menggunakan Model Peta Konsep Mata Pelajaran Kelistrikan Otomotif pada Kelas XI SMK Teknologi Somba Opu Kabupaten Gowa

Identifikasi Pemahaman Siswa Dengan Menggunakan Evaluasi Model Peta Konsep Mata Pelajaran Kelistrikan Otomotif Pada Siswa Kelas XI SMK Teknologi Somba Opu Kabupaten Gowa. Skripsi. Jurusan Pendidikan Teknik Otomotif, Fakultas Teknik, Universitas Negeri Makassar. Penelitian ini merupakan penelitian ex-post facto dalam bentuk deskriptif yang melibatkan variabel tunggal, yaitu pemahaman yang diidentifikasi dengan cara evaluasi model peta konsep. populasi penelitian ini adalah siswa kelas XI SMK Teknologi Somba Opu Kabupaten Gowa pada tahun pelajaran 2010/2011 sebanyak 120 siswa yang tersebar pada 3 kelas. Sampel yang dipilih secara acak sebanyak 30 siswa. Data dalam penelitian ini dikumpulkan melalui dua cara : Nilai siswa yang diperoleh melalui evaluasi multiple choice sebagai data pembanding dan nilai siswa yang diperoleh melalui evaluasi model peta konsep. Hasil penelitian ini dianalisis menggunakan deskriptif inferential, Selanjutnya data tersebut dideskriptifkan. Berdasarkan hasil analisis data dan pembahasannya dapat disimpulkan bahwa pemahaman kelistrikan otomotif siswa kelas XI SMK Teknologi Somba Opu kabupaten gowa yang diidentifikasi dengan evaluasi multiple choice oleh guru bidang studi berada pada kategori tinggi dengan persentase skor ≥ 43,33% sedangkan identifikasi pemahaman siswa oleh peneliti menggunakan evaluasi model peta konsep berada pada kategori rendah dengan persentase skor ≤ 30,00% dengan siswa yang sama. Melihat hal tersebut maka dapat disimpulkan bahwa evaluasi model peta konsep lebih ideal digunakan dalam mengevaluasi pemahaman konsep siswa karena gambaran pemahaman siswa terlihat pada diagram pemetaan konsep