16 research outputs found

    Effect of Portuguese Man-of-War Venom on Isolated Vascular Segments

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    ABSTRACT The purpose of this study was to characterize the mode of action of nematocyst venom from the Portuguese man-of-wa

    Identification of membrane-associated lymphotoxin (LT) on mitogen-activated human lymphocytes using heterologous anti-LT antisera in vitro

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    Surface-associated lymphotoxin (LT) molecules have been identified on mitogen-activated human lymphocytes employing heterologous anti-α-LT serum in vitro. These membrane-associated LT molecules are present on PHA- or Con A-activated lymphocytes but do not appear to be expressed on unstimulated cells. Furthermore, these molecules were detected primarily on activated T lymphocytes, with little detectable on activated B- or null-cell populations. The removal of surface LT-bearing lymphocytes, using anti-α-LT serum + C′, does not dramatically affect the capacity of the remaining cells to release LT after mitogen restimulation. In addition, the presence of toxic molecules on the surface of activated lymphocytes suggests that these materials may be expressed in an inactive, noncytotoxic form. © 1977

    Control of Cnida Discharge: I. Evidence for Two Classes of Chemoreceptor

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    Volume: 174Start Page: 163End Page: 17

    Developmental differences in Ca 2

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