Convergence to the maximal invariant measure for a zero-range process with random rates

We consider a one-dimensional totally asymmetric nearest-neighbor zero-range process with site-dependent jump-rates - an environment. For each environment p we prove that the set of all invariant measures is the convex hull of a set of product measures with geometric marginals. As a consequence we show that for environments p satisfying certain asymptotic property, there are no invariant measures concentrating on configurations with critical density bigger than $\rho^*(p)$, a critical value. If $\rho^*(p)$ is finite we say that there is phase-transition on the density. In this case we prove that if the initial configuration has asymptotic density strictly above $\rho^*(p)$, then the process converges to the maximal invariant measure.Comment: 19 pages, Revised versio

How can allocative inefficiency reveal risk preference? An empirical investigation on French wheat farms

We focus on a simple framework on wheat producer behaviour in a context of price output uncertainty. More precisely, we establish a relationship between ex post output price level and allocative inefficiency that allows to characterize farmers’ risk preferences. Given this analysis, the connection between risk aversion and other socioeconomic variables (such as degree of output specialisation, total asset, debts, farmer’s age…) can furthermore empirically be explored. This relationship is empirically tested on an unbalanced panel including about 650 wheat producers located in the French Department of Meuse over 1992- 2003.Producer behaviour, allocative inefficiency, risk aversion, Crop Production/Industries, Risk and Uncertainty,

CENP-A Is Dispensable for Mitotic Centromere Function after Initial Centromere/Kinetochore Assembly

Human centromeres are defined by chromatin containing the histone H3 variant CENP-A assembled onto repetitive alphoid DNA sequences. By inducing rapid, complete degradation of endogenous CENP-A, we now demonstrate that once the first steps of centromere assembly have been completed in G1/S, continued CENP-A binding is not required for maintaining kinetochore attachment to centromeres or for centromere function in the next mitosis. Degradation of CENP-A prior to kinetochore assembly is found to block deposition of CENP-C and CENP-N, but not CENP-T, thereby producing defective kinetochores and failure of chromosome segregation. Without the continuing presence of CENP-A, CENP-B binding to alphoid DNA sequences becomes essential to preserve anchoring of CENP-C and the kinetochore to each centromere. Thus, there is a reciprocal interdependency of CENP-A chromatin and the underlying repetitive centromere DNA sequences bound by CENP-B in the maintenance of human chromosome segregation

Phosphorylation of CENP-A on serine 7 does not control centromere function

CENP-A is the histone H3 variant necessary to specify the location of all eukaryotic centromeres via its CENP-A targeting domain and either one of its terminal regions. In humans, several post-translational modifications occur on CENP-A, but their role in centromere function remains controversial. One of these modifications of CENP-A, phosphorylation on serine 7, has been proposed to control centromere assembly and function. Here, using gene targeting at both endogenous CENP-A alleles and gene replacement in human cells, we demonstrate that a CENP-A variant that cannot be phosphorylated at serine 7 maintains correct CENP-C recruitment, faithful chromosome segregation and long-term cell viability. Thus, we conclude that phosphorylation of CENP-A on serine 7 is dispensable to maintain correct centromere dynamics and function

A Far-infrared Characterization of 24 μm Selected Galaxies at 0 < z < 2.5 using Stacking at 70 μm and 160 μm in the COSMOS Field

We present a study of the average properties of luminous infrared galaxies detected directly at 24 μm in the COSMOS field using a median stacking analysis at 70 μm and 160 μm. Over 35,000 sources spanning 0 ≤ z ≤ 3 and 0.06 mJy ≤ S_(24) ≤ 3.0 mJy are stacked, divided into bins of both photometric redshift and 24 μm flux. We find no correlation of S_(70)/S_(24) flux density ratio with S_(24), but find that galaxies with higher S_(24) have a lower S_(160)/S_(24) flux density ratio. These observed ratios suggest that 24 μm selected galaxies have warmer spectral energy distributions (SEDs) at higher mid-IR fluxes, and therefore have a possible higher fraction of active galactic nuclei. Comparisons of the average S_(70)/S_(24) and S_(160)/S_(24) colors with various empirical templates and theoretical models show that the galaxies detected at 24 μm are consistent with "normal" star-forming galaxies and warm mid-IR galaxies such as Mrk 231, but inconsistent with heavily obscured galaxies such as Arp 220. We perform a χ^2 analysis to determine best-fit galactic model SEDs and total IR luminosities for each of our bins. We compare our results to previous methods of estimating L IR and find that previous methods show considerable agreement over the full redshift range, except for the brightest S_(24) sources, where they overpredict the bolometric IR luminosity at high redshift, most likely due to their warmer dust SED. We present a table that can be used as a more accurate and robust method for estimating bolometric infrared luminosity from 24 μm flux densities

A 5\u27-uridine Amplifies miRNA/miRNA* Asymmetry in Drosophila by Promoting RNA-induced Silencing Complex Formation

BACKGROUND: MicroRNA (miRNA) are diverse in sequence and have a single known sequence bias: they tend to start with uridine (U). RESULTS: Our analyses of fly, worm and mouse miRNA sequence data reveal that the 5\u27-U is recognized after miRNA production. Only one of the two strands can be assembled into Argonaute protein from a single miRNA/miRNA* molecule: in fly embryo lysate, a 5\u27-U promotes miRNA loading while decreasing the loading of the miRNA*. CONCLUSION: We suggest that recognition of the 5\u27-U enhances Argonaute loading by a mechanism distinct from its contribution to weakening base pairing at the 5\u27-end of the prospective miRNA and, as recently proposed in Arabidopsis and in humans, that it improves miRNA precision by excluding incorrectly processed molecules bearing other 5\u27-nt

Interacting Two-Level Systems as a Source of 1/f Charge Noise in Quantum Dot Qubits

Charge noise in semiconducting quantum dots has been observed to have a 1/f spectrum. We propose a model in which a pair of quantum dots are coupled to a 2D bath of fluctuating two level systems (TLS) that have electric dipole moments and that interact with each other, i.e., with the other fluctuators. These interactions are primarily via the elastic strain field. We use a 2D nearest-neighbor Ising spin glass to represent these elastic interactions and to simulate the dynamics of the bath of electric dipole fluctuators in the presence of a ground plane representing metal gates above the oxide layer containing the fluctuators. The interactions between the TLS cause the energy splitting of individual fluctuators to change with time. We calculate the resulting fluctuations in the electric potential at the two quantum dots that lie below the oxide layer. We find that 1/f electric potential noise spectra at the quantum dots and cross correlation in the noise between the two quantum dots are in qualitative agreement with experiment. Our simulations find that the cross correlations decrease exponentially with increasing quantum dot separation.Comment: 14 pages, 11 figure

Superconducting electromagnetic launch system for civil aircraft

This paper considers the feasibility of different superconducting technologies for electromagnetic launch (EML) to assist civil aircraft take-off. EML has the potential of reducing the required runway length by increasing aircraft acceleration. Expensive airport extensions to face constant air traffic growth could be avoided by allowing large aircraft to operate from short runways at small airports. The new system positively affects total aircraft noise and exhaust emissions near airports and improves overall aircraft efficiency through reducing engine design constraints. Superconducting Linear Synchronous Motors (SCLSMs) can be exploited to deliver the required take-off thrust with electromagnetic performance that cannot be easily achieved by conventional electrical machines. The sizing procedure of a SCLSM able to launch A320 in weight is presented. Electromagnetic and thermal aspects of the machine are taken into account including the modelling of ac losses in superconductors and thermal insulation. The metallic high temperature superconductor (HTS) magnesium diboride (MgB2) is used and operated at 20 K, the boiling temperature of liquid hydrogen. With modern manufacturing technology, multifilament MgB2 wires appear to be the most cost-effective solution for this application. Finally the impact of the cryocooler efficiency on the machine performance is evaluated

Thermal design of linear induction and synchronous motor for electromagnetic launch of civil aircraft

The engine size of modern passenger transport aircraft is principally determined by take-off conditions, since initial acceleration requires maximum engine power. An elec¬tromagnetic launch (EML) system could provide some or all of the energy required at takeoff so that the aircraft engine power requirement and fuel consumption may be significantly reduced. So far, EML for aircraft has been adopted only for military applications to replace steam catapults on the deck of aircraft carriers. This paper will describe the potential application of EML to propel civil aircraft on the runways of modern air¬ports. A comparison of synchronous and asynchronous electrical motor systems designed to launch an A320-200 sized aircraft is presented. The paper also describes a solution of the transient heat transfer problem applied to the conductive components of EML systems