5 research outputs found

    Los resultados de aprendizaje en la mejora de la formación de los alumnos. Profundización a partir de la concreción y formulación inicial para el Máster en Educación Especial de la Facultad de Educación

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    El proyecto, a partir de la formación del profesorado, durante el curso anterior, en la formulación y concreción de resultados de aprendizaje, tiene el objetivo de analizar las posibles lagunas de resultados de aprendizaje del Máster en Educación Especial de la UCM en relación con las competencias del título, así como estudiar la valoración por parte de los alumnos del Máster del fomento de los resultados de aprendizaje propuestos para cada asignatura, así como profundizar en las posibles mejoras en la metodología que podrían favorecer una mejora de la formación en términos de los citados resultados de aprendizaje

    The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies

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    International audienceSignificance There is growing evidence that preexisting autoantibodies neutralizing type I interferons (IFNs) are strong determinants of life-threatening COVID-19 pneumonia. It is important to estimate their quantitative impact on COVID-19 mortality upon SARS-CoV-2 infection, by age and sex, as both the prevalence of these autoantibodies and the risk of COVID-19 death increase with age and are higher in men. Using an unvaccinated sample of 1,261 deceased patients and 34,159 individuals from the general population, we found that autoantibodies against type I IFNs strongly increased the SARS-CoV-2 infection fatality rate at all ages, in both men and women. Autoantibodies against type I IFNs are strong and common predictors of life-threatening COVID-19. Testing for these autoantibodies should be considered in the general population

    The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies

    No full text
    International audienceSignificance There is growing evidence that preexisting autoantibodies neutralizing type I interferons (IFNs) are strong determinants of life-threatening COVID-19 pneumonia. It is important to estimate their quantitative impact on COVID-19 mortality upon SARS-CoV-2 infection, by age and sex, as both the prevalence of these autoantibodies and the risk of COVID-19 death increase with age and are higher in men. Using an unvaccinated sample of 1,261 deceased patients and 34,159 individuals from the general population, we found that autoantibodies against type I IFNs strongly increased the SARS-CoV-2 infection fatality rate at all ages, in both men and women. Autoantibodies against type I IFNs are strong and common predictors of life-threatening COVID-19. Testing for these autoantibodies should be considered in the general population
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