Design of an RSFQ Control Circuit to Observe MQC on an rf-SQUID

We believe that the best chance to observe macroscopic quantum coherence (MQC) in a rf-SQUID qubit is to use on-chip RSFQ digital circuits for preparing, evolving and reading out the qubit's quantum state. This approach allows experiments to be conducted on a very short time scale (sub-nanosecond) without the use of large bandwidth control lines that would couple environmental degrees of freedom to the qubit thus contributing to its decoherence. In this paper we present our design of a RSFQ digital control circuit for demonstrating MQC in a rf-SQUID. We assess some of the key practical issues in the circuit design including the achievement of the necessary flux bias stability. We present an "active" isolation structure to be used to increase coherence times. The structure decouples the SQUID from external degrees of freedom, and then couples it to the output measurement circuitry when required, all under the active control of RSFQ circuits. Research supported in part by ARO grant # DAAG55-98-1-0367.Comment: 4 pages. More information and publications at http://www.ece.rochester.edu:8080/users/sde/research/publications/index.htm

Hybrid Fast Multipole Method Applied to Beam-Beam Collisions in the Strong-Strong Regime

The strong-strong interactions of two colliding beams are simulated by tracking the motion of a set of macroparticles. The field generated by each distribution is evaluated using the Fast Multipole Method (FMM) together with some elements of particle-mesh methods. This technique allows us to check the exact frequencies of the coherent modes and the frequencies of oscillations of individual particles in the beam. The agreement between the simulations and analytical calculations is largely improved. Furthermore it is an efficient method to study the coherent modes in the case of separated beams

LHC On-Line Model

The LHC machine will be a very demanding accelerator from a beam control perspective. There are tight constraints on the key beam parameters in the presence of large non-linearities and dynamic persistent current effects. Particle loss in the LHC must be actively minimized to avoid damage to the machine. Therefore any adjustment to the machine parameters would ideally be checked beforehand with a proper modeling tool. The LHC On-Line Model is an attempt to provide such an analysis tool based mainly on the MAD-X code. The goal is not to provide a real-time interactive system to control the LHC, but rather a way to speed up interaction with the power of MAD-X and to facilitate off-line analysis to give results within appropriate time constraints. There will be a rich spectrum of potential applications such as closed orbit correction, beta-beating analysis, optimization of non-linear correction and knob settings. We report the status of the on-line model software which is at present being developed for the beginning of the LHC commissioning

On the 2d Zakharov system with L^2 Schr\"odinger data

We prove local in time well-posedness for the Zakharov system in two space dimensions with large initial data in L^2 x H^{-1/2} x H^{-3/2}. This is the space of optimal regularity in the sense that the data-to-solution map fails to be smooth at the origin for any rougher pair of spaces in the L^2-based Sobolev scale. Moreover, it is a natural space for the Cauchy problem in view of the subsonic limit equation, namely the focusing cubic nonlinear Schroedinger equation. The existence time we obtain depends only upon the corresponding norms of the initial data - a result which is false for the cubic nonlinear Schroedinger equation in dimension two - and it is optimal because Glangetas-Merle's solutions blow up at that time.Comment: 30 pages, 2 figures. Minor revision. Title has been change

Mutational analysis of BTAF1-TBP interaction: BTAF1 can rescue DNA-binding defective TBP mutants

The BTAF1 transcription factor interacts with TATA-binding protein (TBP) to form the B-TFIID complex, which is involved in RNA polymerase II transcription. Here, we present an extensive mapping study of TBP residues involved in BTAF1 interaction. This shows that residues in the concave, DNA-binding surface of TBP are important for BTAF1 binding. In addition, BTAF1 interacts with residues in helix 2 on the convex side of TBP as assayed in protein-protein and in DNA-binding assays. BTAF1 drastically changes the TATA-box binding specificity of TBP, as it is able to recruit DNA-binding defective TBP mutants to both TATA-containing and TATA-less DNA. Interestingly, other helix 2 interacting factors, such as TFIIA and NC2, can also stabilize mutant TBP binding to DNA. In contrast, TFIIB which interacts with a distinct surface of TBP does not display this activity. Since many proteins contact helix 2 of TBP, this provides a molecular basis for mutually exclusive TBP interactions and stresses the importance of this structural element for eukaryotic transcription

Physics Opportunities with the FCC-hh Injectors

In this chapter we explore a few examples of physics opportunities using the existing chain of accelerators at CERN, including potential upgrades. In this context the LHC ring is also considered as a part of the injector system. The objective is to find examples that constitute sensitive probes of New Physics that ideally cannot be done elsewhere or can be done significantly better at theCERN accelerator complex. Some of these physics opportunities may require a more flexible injector complex with additional functionality than that just needed to inject protons into the FCC-hh at the right energy, intensity and bunch structure. Therefore it is timely to discuss these options concurrently with the conceptual design of the FCC-hh injector system.Comment: 13 pages, chapter 5 in Physics at the FCC-hh, a 100 TeV pp collide