3,058 research outputs found

    Estrés laboral y satisfacción sexual en personal sanitario

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    Job stress and sexual satisfaction are relevant issues in the modern society. Those ones can change notably the life quality of health workers. Also, it is pointed out that health workers are a set of people that has not been studied deepen. This work aimed to determine the job stress and sexual satisfaction in health workers. It was carried out quantitative research of correlational scope with a non-experimental cross-sectional design. The sample selected had 100 workers of health industry that were selected through a non-probabilistic sampling. The sample was conformed of 40% men and 60% women. It was evaluated two kinds of test, the first one was job stress through the scale job stress of the ILO-WHO, and the second one was the new sexual satisfaction scale (NSSS). The results identified a predominant pattern of job stress and a medium level of sexual satisfaction. The sexual satisfaction results did not show meaningful differences based on the statistics between men and women (t (98.0) = -1.56, p >0.05). In addition, it is worth to mention that job stress and sexual satisfaction follow a slightly relation between both (Rho= -0.427 p < .001). Finally, it was concluded that the higher job stress is, the less sexual satisfaction is.   El estrés laboral y la satisfacción sexual representan un problema significativo en la sociedad moderna debido a que puede afectar notablemente en la calidad de vida de los trabajadores, además de ser una asociación que no ha sido estudiada a profundidad, por esta razón la presente investigación tuvo como objetivo determinar la relación entre estrés laboral y satisfacción sexual en el personal sanitario, mediante un enfoque cuantitativo, de alcance correlacional, diseño no experimental de corte transversal, en una muestra conformada de 100 profesionales pertenecientes al área de salud (40% hombres y 60% mujeres) seleccionados mediante un muestreo no probabilístico a quienes se les aplicó la escala de estrés laboral OIT- OMS y la nueva escala de satisfacción sexual (NSSS). Los resultados obtenidos identificaron la predominancia de estrés, así como nivel medio de satisfacción sexual sin diferencias estadísticamente significativas entre hombres y mujeres con relación a la variable satisfacción sexual (t (98.0) = -1.56, p >0.05). Además, existe una relación negativa leve entre estrés laboral y satisfacción sexual (Rho= -0.427 p < .001). Se concluyó que a mayor estrés laboral menor satisfacción sexua

    Job Stress and Sexual Satisfaction in Health Workers

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    El estrés laboral y la satisfacción sexual representan un problema significativo en la sociedad moderna debido a que puede afectar notablemente en la calidad de vida de los trabajadores, además de ser una asociación que no ha sido estudiada a profundidad, por esta razón la presente investigación tuvo como objetivo determinar la relación entre estrés laboral y satisfacción sexual en el personal sanitario, mediante un enfoque cuantitativo, de alcance correlacional, diseño no experimental de corte transversal, en una muestra conformada de 100 profesionales pertenecientes al área de salud (40% hombres y 60% mujeres) seleccionados mediante un muestreo no probabilístico a quienes se les aplicó la escala de estrés laboral OIT- OMS y la nueva escala de satisfacción sexual (NSSS). Los resultados obtenidos identificaron la predominancia de estrés, así como nivel medio de satisfacción sexual sin diferencias estadísticamente significativas entre hombres y mujeres con relación a la variable satisfacción sexual (t (98.0) = -1.56, p >0.05). Además, existe una relación negativa leve entre estrés laboral y satisfacción sexual (Rho= -0.427 p < .001). Se concluyó que a mayor estrés laboral menor satisfacción sexual.Job stress and sexual satisfaction are relevant issues in the modern society. Those ones can change notably the life quality of health workers. Also, it is pointed out that health workers are a set of people that has not been studied deepen. This work aimed to determine the job stress and sexual satisfaction in health workers. It was carried out quantitative research of correlational scope with a non-experimental cross-sectional design. The sample selected had 100 workers of health industry that were selected through a non-probabilistic sampling. The sample was conformed of 40% men and 60% women. It was evaluated two kinds of test, the first one was job stress through the scale job stress of the ILO-WHO, and the second one was the new sexual satisfaction scale (NSSS). The results identified a predominant pattern of job stress and a medium level of sexual satisfaction. The sexual satisfaction results did not show meaningful differences based on the statistics between men and women (t (98.0) = -1.56, p >0.05). In addition, it is worth to mention that job stress and sexual satisfaction follow a slightly relation between both (Rho= -0.427 p < .001). Finally, it was concluded that the higher job stress is, the less sexual satisfaction is.&nbsp

    Job Stress and Sexual Satisfaction in Health Workers

    Get PDF
    El estrés laboral y la satisfacción sexual representan un problema significativo en la sociedad moderna debido a que puede afectar notablemente en la calidad de vida de los trabajadores, además de ser una asociación que no ha sido estudiada a profundidad, por esta razón la presente investigación tuvo como objetivo determinar la relación entre estrés laboral y satisfacción sexual en el personal sanitario, mediante un enfoque cuantitativo, de alcance correlacional, diseño no experimental de corte transversal, en una muestra conformada de 100 profesionales pertenecientes al área de salud (40% hombres y 60% mujeres) seleccionados mediante un muestreo no probabilístico a quienes se les aplicó la escala de estrés laboral OIT- OMS y la nueva escala de satisfacción sexual (NSSS). Los resultados obtenidos identificaron la predominancia de estrés, así como nivel medio de satisfacción sexual sin diferencias estadísticamente significativas entre hombres y mujeres con relación a la variable satisfacción sexual (t (98.0) = -1.56, p >0.05). Además, existe una relación negativa leve entre estrés laboral y satisfacción sexual (Rho= -0.427 p < .001). Se concluyó que a mayor estrés laboral menor satisfacción sexual.Job stress and sexual satisfaction are relevant issues in the modern society. Those ones can change notably the life quality of health workers. Also, it is pointed out that health workers are a set of people that has not been studied deepen. This work aimed to determine the job stress and sexual satisfaction in health workers. It was carried out quantitative research of correlational scope with a non-experimental cross-sectional design. The sample selected had 100 workers of health industry that were selected through a non-probabilistic sampling. The sample was conformed of 40% men and 60% women. It was evaluated two kinds of test, the first one was job stress through the scale job stress of the ILO-WHO, and the second one was the new sexual satisfaction scale (NSSS). The results identified a predominant pattern of job stress and a medium level of sexual satisfaction. The sexual satisfaction results did not show meaningful differences based on the statistics between men and women (t (98.0) = -1.56, p >0.05). In addition, it is worth to mention that job stress and sexual satisfaction follow a slightly relation between both (Rho= -0.427 p < .001). Finally, it was concluded that the higher job stress is, the less sexual satisfaction is.&nbsp

    Effect of substrate thermal resistance on space-domain microchannel

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    In recent years, Fluorescent Melting Curve Analysis (FMCA) has become an almost ubiquitous feature of commercial quantitative PCR (qPCR) thermal cyclers. Here a micro-fluidic device is presented capable of performing FMCA within a microchannel. The device consists of modular thermally conductive blocks which can sandwich a microfluidic substrate. Opposing ends of the blocks are held at differing temperatures and a linear thermal gradient is generated along the microfluidic channel. Fluorescent measurements taken from a sample as it passes along the micro-fluidic channel permits fluorescent melting curves to be generated. In this study we measure DNA melting temperature from two plasmid fragments. The effects of flow velocity and ramp-rate are investigated, and measured melting curves are compared to those acquired from a commercially available PCR thermocycler

    Effects of vessel traffic on relative abundance and behaviour of cetaceans : the case of the bottlenose dolphins in the Archipelago de La Maddalena, north-western Mediterranean sea

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    Acknowledgements This study was part of the Tursiops Project of the Dolphin Research Centre of Caprera, La Maddalena. Financial and logistical support was provided by the Centro Turistico Studentesco (CTS) and by the National Park of the Archipelago de La Maddalena. We thank the Natural Reserve of Bocche di Bonifacio for the support provided during data collection. The authors thank the numerous volunteers of the Caprera Dolphin Research Centre and especially Marco Ferraro, Mirko Ugo, Angela Pira and Maurizio Piras whose assistance during field observation and skills as a boat driver were invaluable.Peer reviewedPostprin

    The Prevalence of Latent Mycobacterium Tuberculosis Infection Based on an Interferon-γ Release Assay: A Cross-Sectional Survey Among Urban Adults in Mwanza, Tanzania.

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    One third of the world's population is estimated to be latently infected with Mycobacterium tuberculosis (LTBI). Surveys of LTBI are rarely performed in resource poor TB high endemic countries like Tanzania although low-income countries harbor the largest burden of the worlds LTBI. The primary objective was to estimate the prevalence of LTBI in household contacts of pulmonary TB cases and a group of apparently healthy neighborhood controls in an urban setting of such a country. Secondly we assessed potential impact of LTBI on inflammation by quantitating circulating levels of an acute phase reactant: alpha-1-acid glycoprotein (AGP) in neighborhood controls. The study was nested within the framework of two nutrition studies among TB patients in Mwanza, Tanzania. Household contacts- and neighborhood controls were invited to participate. The study involved a questionnaire, BMI determination and blood samples to measure AGP, HIV testing and a Quantiferon Gold In tube (QFN-IT) test to detect signs of LTBI. 245 household contacts and 192 neighborhood controls had available QFN-IT data. Among household contacts, the proportion of QFT-IT positive was 59% compared to 41% in the neighborhood controls (p = 0.001). In a linear regression model adjusted for sex, age, CD4 and HIV, a QFT-IT positive test was associated with a 10% higher level of alpha-1-acid glycoprotein(AGP) (10(B) 1.10, 95% CI 1.01; 1.20, p = 0.03), compared to individuals with a QFT-IT negative test. LTBI is highly prevalent among apparently healthy urban Tanzanians even without known exposure to TB in the household. LTBI was found to be associated with elevated levels of AGP. The implications of this observation merit further studies

    Discovery of the first dual GSK3 beta inhibitor/Nrf2 inducer. A new multitarget therapeutic strategy for Alzheimer's disease

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    The formation of neurofibrillary tangles (NFTs), oxidative stress and neuroinflammation have emerged as key targets for the treatment of Alzheimer’s disease (AD), the most prevalent neurodegenerative disorder. These pathological hallmarks are closely related to the over-activity of the enzyme GSK3β and the downregulation of the defense pathway Nrf2-EpRE observed in AD patients. Herein, we report the synthesis and pharmacological evaluation of a new family of multitarget 2,4-dihydropyrano[2,3-c]pyrazoles as dual GSK3β inhibitors and Nrf2 inducers. These compounds are able to inhibit GSK3β and induce the Nrf2 phase II antioxidant and anti-inflammatory pathway at micromolar concentrations, showing interesting structure-activity relationships. The association of both activities has resulted in a remarkable anti-inflammatory ability with an interesting neuroprotective profile on in vitro models of neuronal death induced by oxidative stress and energy depletion and AD. Furthermore, none of the compounds exhibited in vitro neurotoxicity or hepatotoxicity and hence they had improved safety profiles compared to the known electrophilic Nrf2 inducers. In conclusion, the combination of both activities in this family of multitarget compounds confers them a notable interest for the development of lead compounds for the treatment of AD

    Mapping gene associations in human mitochondria using clinical disease phenotypes

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    Nuclear genes encode most mitochondrial proteins, and their mutations cause diverse and debilitating clinical disorders. To date, 1,200 of these mitochondrial genes have been recorded, while no standardized catalog exists of the associated clinical phenotypes. Such a catalog would be useful to develop methods to analyze human phenotypic data, to determine genotype-phenotype relations among many genes and diseases, and to support the clinical diagnosis of mitochondrial disorders. Here we establish a clinical phenotype catalog of 174 mitochondrial disease genes and study associations of diseases and genes. Phenotypic features such as clinical signs and symptoms were manually annotated from full-text medical articles and classified based on the hierarchical MeSH ontology. This classification of phenotypic features of each gene allowed for the comparison of diseases between different genes. In turn, we were then able to measure the phenotypic associations of disease genes for which we calculated a quantitative value that is based on their shared phenotypic features. The results showed that genes sharing more similar phenotypes have a stronger tendency for functional interactions, proving the usefulness of phenotype similarity values in disease gene network analysis. We then constructed a functional network of mitochondrial genes and discovered a higher connectivity for non-disease than for disease genes, and a tendency of disease genes to interact with each other. Utilizing these differences, we propose 168 candidate genes that resemble the characteristic interaction patterns of mitochondrial disease genes. Through their network associations, the candidates are further prioritized for the study of specific disorders such as optic neuropathies and Parkinson disease. Most mitochondrial disease phenotypes involve several clinical categories including neurologic, metabolic, and gastrointestinal disorders, which might indicate the effects of gene defects within the mitochondrial system. The accompanying knowledgebase (http://www.mitophenome.org/) supports the study of clinical diseases and associated genes

    Remote Manipulation of Droplets on a Flexible Magnetically Responsive Film

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    The manipulation of droplets is used in a wide range of applications, from lab-on-a-chip devices to bioinspired functional surfaces. Although a variety of droplet manipulation techniques have been proposed, active, fast and reversible manipulation of pure discrete droplets remains elusive due to the technical limitations of previous techniques. Here, we describe a novel technique that enables active, fast, precise and reversible control over the position and motion of a pure discrete droplet with only a permanent magnet by utilizing a magnetically responsive flexible film possessing actuating hierarchical pillars on the surface. This magnetically responsive surface shows reliable actuating capabilities with immediate field responses and maximum tilting angles of ???90??. Furthermore, the magnetic responsive film exhibits superhydrophobicity regardless of tilting angles of the actuating pillars. Using this magnetically responsive film, we demonstrate active and reversible manipulation of droplets with a remote magnetic force.open0
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