5 research outputs found
Efecto de una suplementación láctea con ácido linoleico conjugado sobre el control de peso y la composición corporal de personas sanas con sobrepeso
Introduction: Conjugated linoleic acids (CLAs) have
shown beneficial effects in weight control therapy however
this relation is not clear.
Objetive: The aim of the study was to examine the effects
and safety of 3 g of a 1:1 mix of c9-t11 and t10-c12 on weight
control and body composition in healthy overweight individuals.
Methods: A prospective, placebo-controlled, randomised
double-blind, parallel clinical trial lasting 24 weeks was
carried out in 38 volunteers (29w, 9m) aged 30-55 years and
BMI ≥27-<30 kg/m2 who consumed 200 ml/day of skimmed
milk with 3g of CLAs or 3g olive oil (placebo). Anthropometric,
biochemical and dual x-ray absorptiometry (DXA)
tests were measured. Diet and physical activity were
assessed.
Results: Subjects maintained their habitual dietary and
exercise patterns over the study. Only CLA group showed a
significant decrease in weight (74.43 ± 10.45 vs 73.54 ± 11.66
kg, p = 0.029) and waist circumference (91.45 ± 10.33 vs
90.65 ± 9.84 cm, p = 0.012) between baseline and end of the
study. BMI and waist height ratio decreased (28.44 ± 1.08 vs
27.81 ± 1.43 kg/m2, p = 0.030 and 0.57 ± 0.05 vs 0.56 ± 0.04 p
= 0.013 respectively) in CLA group at the end. CLA group
experienced a reduction in total fat mass after 24 weeks
(38.62 ± 5.02 vs 36.65 ± 5.64%, p = 0.035). No decrease was
observed in Control group. HOMA index had no changes.
Conclusions: The consumption of skimmed milk enriched
with 3g of a 1:1 mixture of c9-t11 and t10-c12 for 24
weeks led to a decrease in body weight and total fat mass in
healthy, overweight subjects who maintained habitual
diets and exercise patterns. No adverse effects were
observed. Registered under ClinicalTrials.gov Identifier
No. NCT01503047Introducción: Los ácidos linoleicos conjugados (ALC) han
mostrado unos efectos beneficiosos en el tratamiento del control
de peso; sin embargo, esta relación no está clara.
Objetivo: El propósito de este estudio fue examinar los efectos y
la seguridad de 3 g de una mezcla 1:1 de c9-t11 y t10-c12 sobre el
control de peso y la composición corporal en individuos sanos con
sobrepeso.
Métodos: Se realizó un estudio clínico prospectivo, de grupos
paralelos, de distribución aleatoria, a doble ciego y con control
placebo, de 24 semanas de duración, en 38 voluntarios (29 mujeres,
9 hombres) con edades de 30-55 años y un IMC ≥27- < 30
kg/m2 que consumieron 200 ml/día de leche desnatada con 3 g de
ALC o 3 g de aceite de oliva (placebo). Se midieron datos de
antropometría, bioquímica y absorciometría dual de rayos X
(DXA). Se evaluaron la dieta y la actividad física.
Resultados: Los sujetos mantuvieron sus patrones habituales
de dieta y ejercicio a lo largo del estudio. Sólo el grupo de ALC
mostró una reducción significativa del peso (74,43 ± 10,45 vs
73,54 ± 11,66 kg, p = 0,029) y de la circunferencia de la cintura
(91,45 ± 10,33 vs 90,65 ± 9,84 cm, p = 0,012) entre el periodo
basal y el final del estudio. El IMC y el cociente cintura/talla disminuyeron
(28,44 ± 1,08 vs 27,81 ± 1,43 kg/m2, p = 0,030 y 0,57 ±
0,05 vs 0,56 ± 0,04 p = 0,013, respectivamente) en el grupo ALC
al final del estudio. El grupo ALC experimentó una reducción
de la masa grasa total tras 24 semanas (38,62 ± 5,02 vs 36,65 ±
5,64 %, p = 0,035). No se observó reducción en el grupo control.
El índice HOMA no experimentó cambios.
Conclusiones: El consumo de leche desnatada enriquecida
con 3 g de una mezcla 1:1 de c9-t11 y t10-c12 durante 24 semanas
produjo un descenso del peso corporal y la masa grasa total en
sujetos sanos con sobrepeso que mantuvieron sus patrones habituales
de dieta y ejercicio físico. No se observaron efectos adversos.
Registrado con el identificador núm. NCT01503047 en ClinicalTrials.
govThis study was funded by CAPSA (Corporación Alimentaria Peñasanta
Exploring long COVID condition in Latin America: Its impact on patients’ activities and associated healthcare use
"Background: Studies exploring long COVID condition (LCC) in low- and
middle-income countries are scarce. Further characterization of LCC patients
experiencing activity limitations and their associated healthcare use is needed.
This study aimed to describe LCC patients’ characteristics, its impact on activities,
and associated healthcare use in Latin America (LATAM).
Participants: Individuals who (cared for someone or) had COVID-19 and could
read, write, and comprehend Spanish and lived in a LATAM country were invited
to complete a virtual survey. Sociodemographic characteristics, COVID-19 and
LCC symptoms, activity limitations, and healthcare use.
Results: Data from 2,466 people from 16 countries in LATAM were analyzed
(females = 65.9%; mean age of 39.5 ± 53.3 years). 1,178 (48%) of the respondents
had LCC symptoms (≥3 months). These were more likely to have COVID-19 earlier
in the pandemic, were older, had no COVID vaccines, had more comorbidities,
needed supplementary oxygen, and reported significantly more COVID-19
symptoms during the infectious period. 33% of the respondents visited a primary
care provider, 13% went to the emergency department, 5% were hospitalized,
21% visited a specialist, and 32% consulted ≥1 therapist for LCC symptoms
mainly extreme fatigue, sleep difficulties, headaches, muscle or joint pain, and
shortness of breath with activity. The most consulted therapists were respiratory
therapists (15%) and psychologists (14%), followed by physical therapists (13%),
occupational therapists (3%), and speech pathologists (1%). One-third of LCC
respondents decreased their regular activities (e.g., work, school) and 8% needed
help with activities of daily living (ADLs). LCC respondents who reduced their
activities reported more difficulty sleeping, chest pain with activity, depression,
and problems with concentration, thinking, and memory, while those who
needed help with ADLs were more likely to have difficulty walking, and shortness
of breath at rest. Approximately 60% of respondents who experienced activity
limitations sought a specialist and 50% consulted therapists. Conclusions and relevance: Results supported previous findings in terms of the
LCC demographics, and provided insight into LCC impact on patients’ activities
and healthcare services used in LATAM. This information is valuable to inform
service planning and resource allocation in alignment with the needs of this
population.
Exploring long COVID condition in Latin America: Its impact on patients’ activities and associated healthcare use
BackgroundStudies exploring long COVID condition (LCC) in low- and middle-income countries are scarce. Further characterization of LCC patients experiencing activity limitations and their associated healthcare use is needed. This study aimed to describe LCC patients’ characteristics, its impact on activities, and associated healthcare use in Latin America (LATAM).ParticipantsIndividuals who (cared for someone or) had COVID-19 and could read, write, and comprehend Spanish and lived in a LATAM country were invited to complete a virtual survey. Sociodemographic characteristics, COVID-19 and LCC symptoms, activity limitations, and healthcare use.ResultsData from 2,466 people from 16 countries in LATAM were analyzed (females = 65.9%; mean age of 39.5 ± 53.3 years). 1,178 (48%) of the respondents had LCC symptoms (≥3 months). These were more likely to have COVID-19 earlier in the pandemic, were older, had no COVID vaccines, had more comorbidities, needed supplementary oxygen, and reported significantly more COVID-19 symptoms during the infectious period. 33% of the respondents visited a primary care provider, 13% went to the emergency department, 5% were hospitalized, 21% visited a specialist, and 32% consulted ≥1 therapist for LCC symptoms mainly extreme fatigue, sleep difficulties, headaches, muscle or joint pain, and shortness of breath with activity. The most consulted therapists were respiratory therapists (15%) and psychologists (14%), followed by physical therapists (13%), occupational therapists (3%), and speech pathologists (1%). One-third of LCC respondents decreased their regular activities (e.g., work, school) and 8% needed help with activities of daily living (ADLs). LCC respondents who reduced their activities reported more difficulty sleeping, chest pain with activity, depression, and problems with concentration, thinking, and memory, while those who needed help with ADLs were more likely to have difficulty walking, and shortness of breath at rest. Approximately 60% of respondents who experienced activity limitations sought a specialist and 50% consulted therapists.Conclusions and relevanceResults supported previous findings in terms of the LCC demographics, and provided insight into LCC impact on patients’ activities and healthcare services used in LATAM. This information is valuable to inform service planning and resource allocation in alignment with the needs of this population
Development and Application of Bioactive Bi-Layer Edible Films Based on Starch and LAB-Fermented Whey and/or Mango Solution
This study aimed to develop bioactive bi-layer edible films based on starch (primary layer) and LAB-fermented whey and/or mango pulp powder solutions (secondary layer). Bioactive bi-layer edible films were evaluated for their physical properties, mechanical properties, antioxidant capacity, and Lactobacillus rhamnosus availability for 28 days (4 and 20 °C). Selected bioactive bi-layer edible film was applied to sushi to evaluate its sensory acceptance. The results indicated that bi-layer edible films based on LAB-fermented whey/mango solutions presented a higher quantity of phenolic compounds (95.87–107.67 mg GAE/100 g) and higher antioxidant capacity (74.84–77.64%). In addition, the higher viability (106–107 CFU/g) of L. rhamnosus after edible film production was obtained in those formulated with whey. After the storage period, the antioxidant capacity of all edible films was significantly affected by the storage time, while edible films containing whey in their formulation and stored at 4 °C had a L. rhamnosus count higher than 6 log cycles, which is the minimum required threshold to exert its beneficial effects in humans. The sushi covered with the selected bi-layer edible film was well accepted by the consumers, showing acceptance values between “I like it” and “I like it much”. Therefore, the developed bi-layer edible films can serve as an alternative for adding health-promoting compounds to sushi with an adequate sensory acceptance of the consumers
Data_Sheet_1_Exploring long COVID condition in Latin America: Its impact on patients’ activities and associated healthcare use.docx
BackgroundStudies exploring long COVID condition (LCC) in low- and middle-income countries are scarce. Further characterization of LCC patients experiencing activity limitations and their associated healthcare use is needed. This study aimed to describe LCC patients’ characteristics, its impact on activities, and associated healthcare use in Latin America (LATAM).ParticipantsIndividuals who (cared for someone or) had COVID-19 and could read, write, and comprehend Spanish and lived in a LATAM country were invited to complete a virtual survey. Sociodemographic characteristics, COVID-19 and LCC symptoms, activity limitations, and healthcare use.ResultsData from 2,466 people from 16 countries in LATAM were analyzed (females = 65.9%; mean age of 39.5 ± 53.3 years). 1,178 (48%) of the respondents had LCC symptoms (≥3 months). These were more likely to have COVID-19 earlier in the pandemic, were older, had no COVID vaccines, had more comorbidities, needed supplementary oxygen, and reported significantly more COVID-19 symptoms during the infectious period. 33% of the respondents visited a primary care provider, 13% went to the emergency department, 5% were hospitalized, 21% visited a specialist, and 32% consulted ≥1 therapist for LCC symptoms mainly extreme fatigue, sleep difficulties, headaches, muscle or joint pain, and shortness of breath with activity. The most consulted therapists were respiratory therapists (15%) and psychologists (14%), followed by physical therapists (13%), occupational therapists (3%), and speech pathologists (1%). One-third of LCC respondents decreased their regular activities (e.g., work, school) and 8% needed help with activities of daily living (ADLs). LCC respondents who reduced their activities reported more difficulty sleeping, chest pain with activity, depression, and problems with concentration, thinking, and memory, while those who needed help with ADLs were more likely to have difficulty walking, and shortness of breath at rest. Approximately 60% of respondents who experienced activity limitations sought a specialist and 50% consulted therapists.Conclusions and relevanceResults supported previous findings in terms of the LCC demographics, and provided insight into LCC impact on patients’ activities and healthcare services used in LATAM. This information is valuable to inform service planning and resource allocation in alignment with the needs of this population.</p