3,072 research outputs found
Dialogical self strategies of self-organization: psychotherapy and restructuring of internal management
A identidade tem sido um conceito central na literatura em psicologia e na forma como as diferentes abordagens terapêuticas têm concebido os processos de mudança. Entre as inúmeras perspectivas desenvolvidas sobre essa dimensão do ser humano, destacamos o paradigma dialógico que tem vindo a influenciar de forma crescente a teoria e prática em psicoterapia. Segundo esta perspectiva, a funcionalidade psicológica está relacionada com o modo como os indivíduos conseguem articular e colocar em diálogo produtivo as suas várias vozes ou posições de identidade. Neste artigo apresentamos uma revisão da literatura sobre as estratégias que subjazem a essa capacidade auto-organizadora do sistema identitário e sobre as diretrizes que poderão orientar uma intervenção terapêutica dialógica quando essa capacidade se torna disfuncional.Self-concept has been playing a crucial role in psychological literature and in the way the different therapeutic approaches conceive the processes of change. From the diverse perspectives developed about this human dimension, we emphasise the dialogical paradigm that has been increasingly influential in the psychotherapeutic theory and practice. According to the dialogical perspective the psychological well-being is dependent on the way individuals articulate and maintain productive dialogues between the different voices of the self or “I-Positions”. In this paper we present a review of the literature on the strategies that underlie this self-regulatory ability of the self-system and the guidelines of the dialogical therapeutic intervention that could be used when these self-regulatory strategies become dysfunctional.(undefined
Grasping the dialogical nature of acculturation
In this interesting article, Andreouli (2013). Identity and acculturation: The case of
naturalised citizens in Britain. Culture & Psychology, 19, 1–47) presents a dialogical perspective
on acculturation. To support this perspective, the author integrates the
Dialogical Self Theory and the Social Representations Theory. Drawing on her theoretical
explanation, we develop a conceptual review focused on two pairs of constructs –
social representations/I-positions and polyphasia/polyphonia. Andreouli’s empirical
study allowed her to operationalize some critiques about the two-dimensional perspective
and its strategies on acculturation. Nevertheless, it seems that the author ends up
replicating a more conventional and dual way of thinking. Their results give us privileged
access to the negotiation of meanings and activation of promoter signs or, in other
words, to the dialogical dynamics between I-positions. In this respect, we suggest that
the assumption of a more dialogic and semiotic lens could be an interesting further
development to this study
Olfactomedin 4 Serves as a Marker for Disease Severity in Pediatric Respiratory Syncytial Virus (RSV) Infection
Funding: Statement of financial support: The study was financially supported by the VIRGO consortium, an Innovative Cluster approved by the Netherlands Genomics Initiative and partially funded by the Dutch Government (BSIK 03012). The authors have indicated they have no personal financial relationships relevant to this article to disclose. Data Availability Statement: The data is accessible at http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE69606.Peer reviewedPublisher PD
Triple minima in free energy of semiflexible polymers
We study the free energy of the worm-like-chain model, in the
constant-extension ensemble, as a function of the stiffness for finite chains
of length L. We find that the polymer properties obtained in this ensemble are
"qualitatively" different from those obtained using constant-force ensembles.
In particular we find that as we change the stiffness parameter, the polymer
makes a transition from the flexible to the rigid phase and there is an
intermediate regime of parameter values where the free energy has three minima
and both phases are stable. This leads to interesting features in the
force-extension curves.Comment: Published version, 4 pages, 5 figures, revte
Outcome of Colonic Surgery in Elderly Patients with Colon Cancer
Introduction. Colonic cancer is one of the most
commonly diagnosed malignancies and most often occurs in patients
aged 65 years or older. Aim. To evaluate the
outcome of colonic surgery in the elderly in our hospital and to
compare five-year survival rates between the younger and elderly
patients. Methods. 207 consecutive patients
underwent surgery for colon cancer. Patients were separated in
patients younger than 75 and older than 75 years.
Results. Elderly patients presented significantly
more (P < .05) as a surgical emergency, had a longer duration of
admission and were more often admitted to the ICU (P < .01). Also, elderly patients had significant more
co-morbidities, especially cardiovascular pathology (P < .01). Post-operative complications were seen more often in
the elderly, although no significant difference was seen in
anastomotic leakage. The five-year survival rate in the younger
group was 62% compared with 36% in the elderly (P < .05). DFS was 61% in the younger patients compared
with 32% in the elderly (P < .05). Conclusion. Curative resection of
colonic carcinoma in the elderly is well tolerated and age alone
should not be an indication for less aggressive therapy. However,
the type and number of co-morbidities influence post-operative
mortality and morbidity
Reservoir Computing Approach to Robust Computation using Unreliable Nanoscale Networks
As we approach the physical limits of CMOS technology, advances in materials
science and nanotechnology are making available a variety of unconventional
computing substrates that can potentially replace top-down-designed
silicon-based computing devices. Inherent stochasticity in the fabrication
process and nanometer scale of these substrates inevitably lead to design
variations, defects, faults, and noise in the resulting devices. A key
challenge is how to harness such devices to perform robust computation. We
propose reservoir computing as a solution. In reservoir computing, computation
takes place by translating the dynamics of an excited medium, called a
reservoir, into a desired output. This approach eliminates the need for
external control and redundancy, and the programming is done using a
closed-form regression problem on the output, which also allows concurrent
programming using a single device. Using a theoretical model, we show that both
regular and irregular reservoirs are intrinsically robust to structural noise
as they perform computation
Precise determination of low energy electronuclear Hamiltonian for LiYHoF
We use complementary optical spectroscopy methods to directly measure the
lowest crystal-field energies of the rare-earth quantum magnet
LiYHoF, including their hyperfine splittings, with more
than 10 times higher resolution than previous work. We are able to observe
energy level splittings due to the and
isotopes, as well as non-equidistantly spaced hyperfine transitions originating
from dipolar and quadrupolar hyperfine interactions. We provide refined crystal
field parameters and extract the dipolar and quadrupolar hyperfine constants
and
, respectively. Thereupon we determine all crystal-field
energy levels and magnetic moments of the ground state manifold,
including the (non-linear) hyperfine corrections. The latter match the
measurement-based estimates. The scale of the non-linear hyperfine corrections
sets an upper bound for the inhomogeneous line widths that would still allow
for unique addressing of a selected hyperfine transition. e.g. for quantum
information applications. Additionally, we establish the far-infrared,
low-temperature refractive index of LiYHoF.Comment: 9 pages, 6 Figures, 3 Table
Nonuniversal Effects in the Homogeneous Bose Gas
Effective field theory predicts that the leading nonuniversal effects in the
homogeneous Bose gas arise from the effective range for S-wave scattering and
from an effective three-body contact interaction. We calculate the leading
nonuniversal contributions to the energy density and condensate fraction and
compare the predictions with results from diffusion Monte Carlo calculations by
Giorgini, Boronat, and Casulleras. We give a crude determination of the
strength of the three-body contact interaction for various model potentials.
Accurate determinations could be obtained from diffusion Monte Carlo
calculations of the energy density with higher statistics.Comment: 24 pages, RevTex, 5 ps figures, included with epsf.te
Improving membrane based multiplex immunoassays for semi-quantitative detection of multiple cytokines in a single sample
BACKGROUND: Inflammatory mediators can serve as biomarkers for the monitoring of the disease progression or prognosis in many conditions. In the present study we introduce an adaptation of a membrane-based technique in which the level of up to 40 cytokines and chemokines can be determined in both human and rodent blood in a semi-quantitative way. The planar assay was modified using the LI-COR (R) detection system (fluorescence based) rather than chemiluminescence and semi-quantitative outcomes were achieved by normalizing the outcomes using the automated exposure settings of the Odyssey readout device. The results were compared to the gold standard assay, namely ELISA. RESULTS: The improved planar assay allowed the detection of a considerably higher number of analytes (n = 30 and n = 5 for fluorescent and chemiluminescent detection, respectively). The improved planar method showed high sensitivity up to 17 pg/ml and a linear correlation of the normalized fluorescence intensity with the results from the ELISA (r = 0.91). CONCLUSIONS: The results show that the membrane-based technique is a semi-quantitative assay that correlates satisfactorily to the gold standard when enhanced by the use of fluorescence and subsequent semi-quantitative analysis. This promising technique can be used to investigate inflammatory profiles in multiple conditions, particularly in studies with constraints in sample sizes and/or budget
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