Novel Echocardiographic Biomarkers in the Management of Atrial Fibrillation

Purpose of Review: Atrial fibrillation (AF) is the most common arrhythmia in adults. The number of patients with AF is anticipated to increase annually, mainly due to the aging population alongside improved arrhythmia detection. AF is associated with a significantly elevated risk of hospitalization, stroke, thromboembolism, heart failure, and all-cause mortality. Echocardiography is one of the key components of routine assessment and management of AF. Therefore, the aim of this review is to briefly summarize current knowledge on “novel” echocardiographic parameters that may be of value in the management of AF patients. Recent Findings: Novel echocardiographic biomarkers and their clinical application related to the management of AF have been taken into consideration. Both standard parameters such as atrial size and volume but also novels like atrial strain and tissue Doppler techniques have been analyzed. Summary: A number of novel echocardiographic parameters have been proven to enable early detection of left atrial dysfunction along with increased diagnosis accuracy. This concerns particularly experienced echocardiographers. Hence, these techniques might improve the prediction of stroke and thromboembolic events among AF patients and need to be further developed and disseminated. Nonetheless, even the standard imaging parameters could be of significant value and should not be discontinued in everyday clinical practice. © 2019, The Author(s)

Nanofabrication with Pulsed Lasers

An overview of pulsed laser-assisted methods for nanofabrication, which are currently developed in our Institute (LP3), is presented. The methods compass a variety of possibilities for material nanostructuring offered by laser–matter interactions and imply either the nanostructuring of the laser-illuminated surface itself, as in cases of direct laser ablation or laser plasma-assisted treatment of semiconductors to form light-absorbing and light-emitting nano-architectures, as well as periodic nanoarrays, or laser-assisted production of nanoclusters and their controlled growth in gaseous or liquid medium to form nanostructured films or colloidal nanoparticles. Nanomaterials synthesized by laser-assisted methods have a variety of unique properties, not reproducible by any other route, and are of importance for photovoltaics, optoelectronics, biological sensing, imaging and therapeutics

Evaluation of Laminated Composite Beam Theory Accuracy

Carbon fiber-reinforced polymer (CFRP) has been widely implemented in electric vehicle bodies and aircraft fuselage structures. The purpose of CFRP is to reduce the weight and impart rigidity in the final product. A beam structure is typically used to bear the structural load, and the rigidity of the beam can be changed by arranging the laminated fibers at different angles. In this study, a composite I-beam is used as an example in engineering components. Because the theoretical model of the superimposed composite I-beam is established, the theoretical formula is based on the theoretical assumptions of the two-dimensional composite beam, and is combined with the traditional composite plate theory to analyze the maximum bending stress, strain, and deflection. During the theoretical derivation, it is assumed that the flanges of the I-beams are divided into narrow and wide flanges. The beams are considered as structures of beams and flatbeds. When a narrow flange is loaded in the side, the wide flange has no lateral deformation, and the lateral moments are neglected. Therefore, the accuracy of this formula needs to be verified. The purpose of this study is to verify the accuracy of theoretical solutions for the deflection and stress analysis of composite beams. A finite element analysis model is used as the basis for comparing the theoretical solutions. The results indicate that when the aspect ratio of the beam is >15, the theoretical solution will have better accuracy. Without the addition of the material, when 0° ply is placed on the outermost layer of the flange of the nonsymmetric beam, the effective rigidity of the beam is increased by 4–5% compared with the symmetrical beam. The accuracy range of the theoretical solution for the composite beams can be accurately defined based on the results of this study