1,318 research outputs found
Mitigating Complex Dust Foregrounds in Future Cosmic Microwave Background Polarization Experiments
archiveprefix: arXiv primaryclass: astro-ph.CO slaccitation: %%CITATION = ARXIV:1709.07897;%%archiveprefix: arXiv primaryclass: astro-ph.CO slaccitation: %%CITATION = ARXIV:1709.07897;%%archiveprefix: arXiv primaryclass: astro-ph.CO slaccitation: %%CITATION = ARXIV:1709.07897;%%P.B.’s research was supported by an appointment to the NASA Postdoctoral Program at the Jet Propulsion Laboratory, California Institute of Technology, administered by Universities Space Research Association under contract with NAS
Precision Optical Measurements and Fundamental Physical Constants
A brief overview is given on precision determinations of values of the
fundamental physical constants and the search for their variation with time by
means of precision spectroscopy in the optical domain
Recent results from the canfranc dark matter search with germanium detectors
Two germanium detectors are currently operating in the Canfranc Underground
Laboratory at 2450 m.w.e looking for WIMP dark matter. One is a 2 kg 76Ge IGEX
detector (RG-2) which has an energy threshold of 4 keV and a low-energy
background rate of about 0.3 c/keV/kg/day. The other is a small (234 g) natural
abundance Ge detector (COSME), of low energy threshold (2.5 keV) and an energy
resolution of 0.4 keV at 10 keV which is looking for WIMPs and for solar
axions. The analysis of 73 kg-days of data taken by COSME in a search for solar
axions via their photon Primakoff conversion and Bragg scattering in the Ge
crystal yields a 95% C.L. limit for the axion-photon coupling g < 2.8 10^-9
GeV^-1. These data, analyzed for WIMP searches provide an exclusion plot for
WIMP-nucleon spin-independent interaction which improves previous plots in the
low mass region. On the other hand, the exclusion plot derived from the 60
kg-days of data from the RG-2 IGEX detector improves the exclusion limits
derived from other ionization (non thermal) germanium detector experiments in
the region of WIMP masses from 30 to 100 GeV recently singled out by the
reported DAMA annual modulation effect.Comment: 6 pages, talk given at IDM2000, York, September 200
Supporting ethical, independent learning behavior among university students in the Arabian Gulf
© Springer International Publishing Switzerland 2014. Students in the Arabian Gulf region and the world over confront plagiarism temptations wittingly or unwittingly due to the multitude of free and easily available electronic sources of information. Rather than develop independent learning skills and academic integrity, students are often taken advantage of by essay mills that sell readymade essays. Instructors at times compound the problem by repeatedly recycling course assignments and tasks. Furthermore, there have been reports of the use of social networking sites for outsourcing and contract cheating in student assignments. This paper discusses how educators in an institution of higher learning in the UAE assist students to develop good academic skills. Data collection is with the use of an online survey questionnaire. Concurring with Wheeler and Anderson (2010) who call for appropriate and comprehensive institutional policies and guidelines for dealing with plagiarism, practical examples of the processes and procedures used at these institutions are provided
Revealing the molecular signatures of host-pathogen interactions.
Advances in sequencing technology and genome-wide association studies are now revealing the complex interactions between hosts and pathogen through genomic variation signatures, which arise from evolutionary co-existence
Respiratory Francisella tularensis Live Vaccine Strain Infection Induces Th17 Cells and Prostaglandin E2, Which Inhibits Generation of Gamma Interferon-Positive T Cells
Two key routes of Francisella tularensis infection are through the skin and airway. We wished to understand how the route of inoculation influenced the primary acute adaptive immune response. We show that an intranasal inoculation of the F. tularensis live vaccine strain (LVS) with a 1,000-fold-smaller dose than an intradermal dose results in similar growth kinetics and peak bacterial burdens. In spite of similar bacterial burdens, we demonstrate a difference in the quality, magnitude, and kinetics of the primary acute T-cell response depending on the route of inoculation. Further, we show that prostaglandin E2 secretion in the lung is responsible for the difference in the gamma interferon (IFN-γ) response. Intradermal inoculation led to a large number of IFN-γ+ T cells 7 days after infection in both the spleen and the lung. In contrast, intranasal inoculation induced a lower number of IFN-γ+ T cells in the spleen and lung but an increased number of Th17 cells in the lung. Intranasal infection also led to a significant increase of prostaglandin E2 (PGE2) in the bronchoalveolar lavage fluid. Inhibition of PGE2 production with indomethacin treatment resulted in increased numbers of IFN-γ+ T cells and decreased bacteremia in the lungs of intranasally inoculated mice. This research illuminates critical differences in acute adaptive immune responses between inhalational and dermal infection with F. tularensis LVS mediated by the innate immune system and PGE2
- …