7,450 research outputs found

    Progress of the Felsenkeller shallow-underground accelerator for nuclear astrophysics

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    Low-background experiments with stable ion beams are an important tool for putting the model of stellar hydrogen, helium, and carbon burning on a solid experimental foundation. The pioneering work in this regard has been done by the LUNA collaboration at Gran Sasso, using a 0.4 MV accelerator. In the present contribution, the status of the project for a higher-energy underground accelerator is reviewed. Two tunnels of the Felsenkeller underground site in Dresden, Germany, are currently being refurbished for the installation of a 5 MV high-current Pelletron accelerator. Construction work is on schedule and expected to complete in August 2017. The accelerator will provide intense, 50 uA, beams of 1H+, 4He+, and 12C+ ions, enabling research on astrophysically relevant nuclear reactions with unprecedented sensitivity.Comment: Submitted to the Proceedings of Nuclei in the Cosmos XIV, 19-24 June 2016, Niigata/Japa

    Std fimbriae-fucose interaction increases Salmonella-induced intestinal inflammation and prolongs colonization

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    Author summary The intestinal epithelium is a crucial biological interface, interacting with both commensal and pathogenic microorganisms. It’s lined with heavily glycosylated proteins and glycolipids which can act as both attachment sites and energy sources for intestinal bacteria. Fut2, the enzyme governing epithelial α1,2-fucosylation, has been implicated in the interaction between microbes and intestinal epithelial cells. Salmonella is one of the most important bacterial gastrointestinal pathogens affecting millions of people worldwide. Salmonella possesses fimbrial and non-fimbrial adhesins which can be used to adhere to host cells. Here we show that Salmonella expresses Std fimbriae in the gastrointestinal tract in vivo and exploit Std fimbriae to bind fucosylated structures in the mucus and on the intestinal epithelium. Furthermore, we demonstrate that the Std fimbriae-fucose interaction is necessary for bacterial colonization of the intestine and for triggering intestinal inflammation. These data lend new insights into bacterial adhesion-epithelial interactions which are essential for bacterial pathogenesis and key factors in determining tissue tropism and host susceptibility to infectious disease

    Excitonic condensate and quasiparticle transport in electron-hole bilayer systems

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    Bilayer electron-hole systems undergo excitonic condensation when the distance d between the layers is smaller than the typical distance between particles within a layer. All excitons in this condensate have a fixed dipole moment which points perpendicular to the layers, and therefore this condensate of dipoles couples to external electromagnetic fields. We study the transport properties of this dipolar condensate system based on a phenomenological model which takes into account contributions from the condensate and quasiparticles. We discuss, in particular, the drag and counterflow transport, in-plane Josephson effect, and noise in the in-plane currents in the condensate state which provides a direct measure of the superfluid collective-mode velocity.Comment: 7 pages, 3 figure

    Section Extension from Hyperbolic Geometry of Punctured Disk and Holomorphic Family of Flat Bundles

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    The construction of sections of bundles with prescribed jet values plays a fundamental role in problems of algebraic and complex geometry. When the jet values are prescribed on a positive dimensional subvariety, it is handled by theorems of Ohsawa-Takegoshi type which give extension of line bundle valued square-integrable top-degree holomorphic forms from the fiber at the origin of a family of complex manifolds over the open unit 1-disk when the curvature of the metric of line bundle is semipositive. We prove here an extension result when the curvature of the line bundle is only semipositive on each fiber with negativity on the total space assumed bounded from below and the connection of the metric locally bounded, if a square-integrable extension is known to be possible over a double point at the origin. It is a Hensel-lemma-type result analogous to Artin's application of the generalized implicit function theorem to the theory of obstruction in deformation theory. The motivation is the need in the abundance conjecture to construct pluricanonical sections from flatly twisted pluricanonical sections. We also give here a new approach to the original theorem of Ohsawa-Takegoshi by using the hyperbolic geometry of the punctured open unit 1-disk to reduce the original theorem of Ohsawa-Takegoshi to a simple application of the standard method of constructing holomorphic functions by solving the d-bar equation with cut-off functions and additional blowup weight functions

    Deterministic Partial Differential Equation Model for Dose Calculation in Electron Radiotherapy

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    Treatment with high energy ionizing radiation is one of the main methods in modern cancer therapy that is in clinical use. During the last decades, two main approaches to dose calculation were used, Monte Carlo simulations and semi-empirical models based on Fermi-Eyges theory. A third way to dose calculation has only recently attracted attention in the medical physics community. This approach is based on the deterministic kinetic equations of radiative transfer. Starting from these, we derive a macroscopic partial differential equation model for electron transport in tissue. This model involves an angular closure in the phase space. It is exact for the free-streaming and the isotropic regime. We solve it numerically by a newly developed HLLC scheme based on [BerCharDub], that exactly preserves key properties of the analytical solution on the discrete level. Several numerical results for test cases from the medical physics literature are presented.Comment: 20 pages, 7 figure

    Neutron flux and spectrum in the Dresden Felsenkeller underground facility studied by moderated 3^3He counters

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    Ambient neutrons may cause significant background for underground experiments. Therefore, it is necessary to investigate their flux and energy spectrum in order to devise a proper shielding. Here, two sets of altogether ten moderated 3^3He neutron counters are used for a detailed study of the ambient neutron background in tunnel IV of the Felsenkeller facility, underground below 45 meters of rock in Dresden/Germany. One of the moderators is lined with lead and thus sensitive to neutrons of energies higher than 10 MeV. For each 3^3He counter-moderator assembly, the energy dependent neutron sensitivity was calculated with the FLUKA code. The count rates of the ten detectors were then fitted with the MAXED and GRAVEL packages. As a result, both the neutron energy spectrum from 10−9^{-9} MeV to 300 MeV and the flux integrated over the same energy range were determined experimentally. The data show that at a given depth, both the flux and the spectrum vary significantly depending on local conditions. Energy integrated fluxes of (0.61±0.05)(0.61 \pm 0.05), (1.96±0.15)(1.96 \pm 0.15), and (4.6±0.4)×10−4(4.6 \pm 0.4) \times 10^{-4} cm−2^{-2} s−1^{-1}, respectively, are measured for three sites within Felsenkeller tunnel IV which have similar muon flux but different shielding wall configurations. The integrated neutron flux data and the obtained spectra for the three sites are matched reasonably well by FLUKA Monte Carlo calculations that are based on the known muon flux and composition of the measurement room walls.Comment: 10 figures, 4 tables; to be published in Phys. Rev.

    The Effect of Splayed Pins on Vortex Creep and Critical Currents

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    We study the effects of splayed columnar pins on the vortex motion using realistic London Langevin simulations. At low currents vortex creep is strongly suppressed, whereas the critical current j_c is enhanced only moderately. Splaying the pins generates an increasing energy barrier against vortex hopping, and leads to the forced entanglement of vortices, both of which suppress creep efficiently. On the other hand splaying enhances kink nucleation and introduces intersecting pins, which cut off the energy barriers. Thus the j_c enhancement is strongly parameter sensitive. We also characterize the angle dependence of j_c, and the effect of different splaying geometries.Comment: 4 figure

    Study of the Decay B(0)(s)→D(*)(s)D(*)(s)

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    This is the publisher's version, also available electronically from http://journals.aps.org/prl/abstract/10.1103/PhysRevLett.99.241801
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