Determining the User Intent of Chinese-English Mixed Language Queries Based On Search Logs

With the increasing number of multilingual web pages on the Internet, multilingual information retrieval has become an important research topic. While queries are the key element of information retrieval process, mixed-language queries have not yet been adequately studied. This study is to determine the user intents of Chinese-English mixed-language queries submitted to a Chinese search engine, and compares the user intents identified by query content to those identified using additional user behavior data (e.g. clicked results, subsequent queries). The preliminary findings present the distributions of user intents by analyzing query only and additional user behavior data, suggesting a specific searching behavior of Chinese-English mixed-language queries users. The findings of this study could provide useful insights in understanding the searching behavior of Chinese-English mixed-language queries users, and enable web search engines to provide users with more relevant results and more precisely targeted sponsored links.ye

Language Nativeness Modulates Physiological Responses to Moral vs. Immoral Concepts in Chinese-English Bilinguals: Evidence from Event-Related Potential and Psychophysiological Measures

Morality has been an integral part of social cognition and our daily life, and different languages may exert distinct impacts on human moral judgment. However, it remains unclear how moral concept is encoded in the bilingual brain. This study, therefore, aimed to explore the emotional and cognitive involvement of bilingual morality judgement by using combined event-related potential (ERP) and psychophysiological (including skin, heart, and pulse) measures. In the experiment, thirty-one Chinese-English bilingual participants were asked to make moral judgments in Chinese and English, respectively. Our results revealed increased early frontal N400 and decreased LPC in L1 moral concept encoding as compared to L2, suggesting that L1 was more reliant on automatic processes and emotions yet less on elaboration. In contrast, L2 moral and immoral concepts elicited enhanced LPC, decreased N400, and greater automatic psychophysiological electrocardiograph responses, which might reflect more elaborate processing despite blunted emotional responses and increased anxiety. Additionally, both behavioral and P200 data revealed a reliable immorality bias across languages. Our results were discussed in light of the dual-process framework of moral judgments and the (dis)embodiment of bilingual processing, which may advance our understanding of the interplay between language and morality as well as between emotion and cognition

Associations between polygenic risk, negative symptoms, and functional connectome topology during a working memory task in early-onset schizophrenia

Working memory (WM) deficit in schizophrenia is thought to arise from a widespread neural inefficiency. However, we do not know if this deficit results from the illness-related genetic risk and influence the symptom burden in various domains, especially in patients who have an early onset illness. We used graph theory to examine the topology of the functional connectome in 99 subjects (27 early-onset schizophrenia (EOS), 24 asymptomatic siblings, and 48 healthy subjects) during an n-back task, and calculated their polygenic risk score (PRS) for susceptibility to schizophrenia. Linear regression analysis was used to test associations of the PRS, clinical symptoms, altered connectomic properties, and WM accuracy in EOS. Indices of small-worldness and segregation were elevated in EOS during the WM task compared with the other two groups; these connectomic aberrations correlated with increased PRS and negative symptoms. In patients with higher polygenic risk, WM performance was lower only when both the connectomic aberrations and the burden of negative symptoms were higher. Negative symptoms had a stronger moderating role in this relationship. Our findings suggest that the aberrant connectomic topology is a feature of WM task performance in schizophrenia; this relates to higher polygenic risk score as well as higher burden of negative symptoms. The deleterious effects of polygenic risk on cognition are played out via its effects on the functional connectome, as well as negative symptoms

The PPARgamma locus makes long-range chromatin interactions with selected tissue-specific gene loci during adipocyte differentiation in a protein kinase A dependent manner

Differentiation signaling results in reprogramming of cellular gene expression that leads to morphological changes and functional specialization of a precursor cell. This global change in gene expression involves temporal regulation of differentiation-specific genes that are located throughout the genome, raising the idea that genome structure may also be re-organized during cell differentiation to facilitate regulated gene expression. Using in vitro adipocyte differentiation as a model, we explored whether gene organization within the nucleus is altered upon exposure of precursor cells to signaling molecules that induce adipogenesis. The peroxisome proliferator-activated receptor gamma (PPARgamma) nuclear hormone receptor is a master determinant of adipogenesis and is required for adipose differentiation. We utilized the chromosome conformation capture (3C) assay to determine whether the position of the PPARgamma locus relative to other adipogenic genes is changed during differentiation. We report that the PPARgamma2 promoter is transiently positioned in proximity to the promoters of genes encoding adipokines and lipid droplet associated proteins at 6 hours post-differentiation, a time that precedes expression of any of these genes. In contrast, the PPARgamma2 promoter was not in proximity to the EF1alpha promoter, which drives expression of a constitutively active, housekeeping gene that encodes a translation elongation factor, nor was the PPARgamma2 promoter in proximity to the promoter driving the expression of the C/EBPalpha regulatory protein. The formation of the long-range, intergenic interactions involving the PPARgamma2 promoter required the regulatory factor C/EBPbeta, elevated cyclic AMP (cAMP) levels, and protein kinase A (PKA) signaling. We conclude that genome organization is dynamically remodeled in response to adipogenic signaling, and we speculate that these transient inter-genic interactions may be formed for the purposes of selecting some of the transcriptionally silent tissue-specific loci for subsequent transcriptional activation

Dual-frequency programmed harmonics modulation-based simultaneous wireless information and power transfer system via a common resonance link

Most simultaneous wireless information and power transmission (SWIPT) systems currently operate at a single frequency, where the power and information transmission affect the resonance state of each other. This paper proposes a structure using dual-frequency programmed harmonics modulation (DFPHM). The primary-side inverter outputs a dual-frequency (DF) wave containing the power transmission and information transmission frequencies, while the DF wave is coupled to the secondary side through a common inductive link. After the power and information are transmitted to the secondary side, they are demodulated in different branches. Wave trappers are designed on each branch to reduce the interference of information transmission on power transmission. There is no tight coupling transformer in the system to inject information, so the system order is not high. Experiments verified that the proposed structure based on DFPHM is effective.Web of Science1210art. no. 418

Optimal planting pattern of cotton is regulated by irrigation amount under mulch drip irrigation

ObjectiveIt is of great importance to explore agronomic management measures for water conservation and cotton yield in arid areas.MethodsA four–year field experiment was conducted to evaluate cotton yield and soil water consumption under four row spacing configurations (high/low density with 66+10 cm wide, narrow row spacing, RS66+10H and RS66+10L; high/low density with 76 cm equal row spacing, RS76H and RS76L) and two irrigation amounts (CI:conventional drip irrigation; LI:limited drip irrigation) during the growing seasons in Shihezi, Xinjiang.ResultsA quadratic relationship was observed between the maximum LAI (LAImax) and seed yield. Canopy apparent transpiration rate(CAT), daily water consumption intensity (DWCI) and crop evapotranspiration (ETC) were positively and linearly correlated with LAI. The seed yields, lint yields, and ETC under CI were 6.6–18.3%,7.1–20.8% and 22.9–32.6%higher than those observed under LI, respectively. The RS66+10H under CI had the highest seed and lint yields. RS76L had an optimum LAImax range, which ensured a higher canopy apparent photosynthesis and daily dry matter accumulation and reached the same yield level as RS66+10H; however, soil water consumption in RS76L was reduced ETC by 51–60 mm at a depth of 20–60 cm at a radius of 19–38 cm from the cotton row,and water use efficiency increased by 5.6–8.3%compared to RS66+10H under CI.ConclusionA 5.0<LAImax<5.5 is optimum for cotton production in northern Xinjiang, and RS76L under CI is recommended for high yield and can further reduce water consumption. Under LI, the seed and lint yield of RS66+10H were 3.7–6.0% and 4.6–6.9% higher than those of RS76L, respectively. In addition, high-density planting can exploit the potential of soil water to increase cotton yields under water shortage conditions

Biogeographic patterns and drivers of soil viromes

Viruses are crucial in shaping soil microbial functions and ecosystems. However, studies on soil viromes have been limited in both spatial scale and biome coverage. Here we present a comprehensive synthesis of soil virome biogeographic patterns using the Global Soil Virome dataset (GSV) wherein we analysed 1,824 soil metagenomes worldwide, uncovering 80,750 partial genomes of DNA viruses, 96.7% of which are taxonomically unassigned. The biogeography of soil viral diversity and community structure varies across different biomes. Interestingly, the diversity of viruses does not align with microbial diversity and contrasts with it by showing low diversity in forest and shrubland soils. Soil texture and moisture conditions are further corroborated as key factors affecting diversity by our predicted soil viral diversity atlas, revealing higher diversity in humid and subhumid regions. In addition, the binomial degree distribution pattern suggests a random co-occurrence pattern of soil viruses. These findings are essential for elucidating soil viral ecology and for the comprehensive incorporation of viruses into soil ecosystem models

Ultrahigh-sensitivity label-free optical fiber biosensor based on a tapered singlemode- no core-singlemode coupler for Staphylococcus aureus detection

An ultra-high sensitivity label-free optical fiber biosensor for inactivated Staphylococcus aureus (S. aureus) detection is proposed and investigated in this study, with additional advantages of robust and stability compared to traditional tapered fiber structure. The proposed fiber biosensor is based on a tapered singlemode- no core-singlemode fiber coupler (SNSFC) structure, where the no core fiber was tapered to small diameter (taper-waist diameter of about 10 µm) and functionalized with the pig immunoglobulin G (IgG) antibody for detection of S. aureus. The measured maximum wavelength shift of the sensor for an S. aureus concentration of 7 × 101 CFU/ml (colony forming unit per milliliter) is 2.04 nm, which is equivalent to a limit of detection (LOD) of 3.1 CFU/ml (a highest LOD reported so far for optical fiber biosensors), considering the maximum wavelength variation of the sensor in phosphate buffered saline (PBS) is ±0.03 nm over 40 minutes, where 3 times of maximum wavelength variation (3 × 0.03 = 0.09 nm) is defined as measurement limit. The response time of the developed fiber sensor is less than 30 minutes. The ultra-sensitive biosensor has potential to be widely applied to various areas such as disease, medical diagnostics and food safety inspection

Ultrahigh-sensitivity label-free singlemode- tapered no core-singlemode fiber immunosensor for Listeria monocytogenes detection

A challenge for optical fiber biosensor is to achieve ultrahigh sensitivity with narrow full width at half maximum (FWHM) of the spectrum. To address this challenge, an ultrahigh-sensitivity microfiber interferometer fiber ring laser (FRL) biosensor is proposed and investigated for Listeria monocytogenes (L. monocytogenes) detection. The fiber biosensor is composed of a singlemode- tapered no core-singlemode (STNS) fiber configuration, which is functionalized with the anti-L. monocytogenes antibodies. An Erbium Doped Fiber Amplifier is applied to the sensor to excite laser and thus reduce the FWHM of the spectrum, which significantly improved the limit of detection (LoD). The proposed STNS FRL biosensor has excellent reproducibility, specificity and sensitivity for L. monocytogenes. The developed STNS FRL biosensor can directly detect L. monocytogenes cells with LoD as low as 1.0 cell/mL, indicating the capability for detecting single cell of L. monocytogenes. Real lettuce and milk samples have been tested and test result in lettuce and milk samples has deviations within ±30% from that of Phosphate-buffered saline (PBS) for L. monocytogenes concentrations vary from 101 to 103 cells/mL(g). The developed STNS FRL biosensor has ultrahigh sensitivity, good stability, reproducibility, and specificity, which has potential applications in diseases/medical diagnostics