4,644 research outputs found

    A systematic review of the barcoding strategy that contributes to COVID-19 diagnostics at a population level

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    The outbreak of SARS-CoV-2 has made us more alert to the importance of viral diagnostics at a population level to rapidly control the spread of the disease. The critical question would be how to scale up testing capacity and perform a diagnostic test in a high-throughput manner with robust results and affordable costs. Here, the latest 26 articles using barcoding technology for COVID-19 diagnostics and biologically-relevant studies are reviewed. Barcodes are molecular tags, that allow proceeding an array of samples at once. To date, barcoding technology followed by high-throughput sequencing has been made for molecular diagnostics for SARS-CoV-2 infections because it can synchronously analyze up to tens of thousands of clinical samples within a short diagnostic time. Essentially, this technology can also be used together with different biotechnologies, allowing for investigation with resolution of single molecules. In this Mini-Review, I first explain the general principle of the barcoding strategy and then put forward recent studies using this technology to accomplish COVID-19 diagnostics and basic research. In the meantime, I provide the viewpoint to improve the current COVID-19 diagnostic strategy with potential solutions. Finally, and importantly, two practical ideas about how barcodes can be further applied in studying SARS-CoV-2 to accelerate our understanding of this virus are proposed

    SURVEYING DAMAGE TO HISTORIC BUILDINGS IN MEINONG EARTHQUAKE

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    [EN] In this paper, according to survey damage to historic building in Meinong earthquake, five damage models for Chinese temple, the state temple of the Martial God are proposed. These temples were built during 1600s. These five damage models are separation of column from wall (M1), roof damage (M3) wall cracks (M5), surface peeling (M6), and Tilt column (M8). Taiwan free field strong earthquake network is used to analyze seismic data from three free field stations. These stations are close to the state temple of the Martial God. Due to forward directivity effect, the stations’ maximum ground acceleration amplitude is dependent of distance between epicenter and station. Modal analysis using finite element method (FEM) is used to detect weak positions of Martial God temple. Weak positions of numerical results are close to site failure positions of Martial God temple.Wang, R.; Chang, H.; Lee, M. (2016). SURVEYING DAMAGE TO HISTORIC BUILDINGS IN MEINONG EARTHQUAKE. En 8th International congress on archaeology, computer graphics, cultural heritage and innovation. Editorial Universitat Politècnica de València. 488-491. https://doi.org/10.4995/arqueologica8.2015.4178OCS48849

    Coexisting Innominate Vein Compression Syndrome and May-Thurner Syndrome

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    AbstractInnominate vein compression syndrome and May-Thurner syndrome (also called iliac vein compression syndrome) are venous compression syndromes caused by normal anatomic structures. Here, we present a case in which these two conditions were found in the same patient using multidetector row computed tomography. This case is significant for two reasons: (1) it is, to the best of our knowledge, the first case study in the literature to report coexisting innominate vein compression syndrome and May-Thurner syndrome; and (2) it shows that multidetector row computed tomography has powerful diagnostic ability for venous diseases
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