Model-based Aeroservoelastic Design and Load Alleviation of Large Wind Turbine Blades

This paper presents an aeroservoelastic modeling approach for dynamic load alleviation in large wind turbines with trailing-edge aerodynamic surfaces. The tower, potentially on a moving base, and the rotating blades are modeled using geometrically non-linear composite beams, which are linearized around reference conditions with arbitrarily-large structural displacements. Time-domain aerodynamics are given by a linearized 3-D unsteady vortexlattice method and the resulting dynamic aeroelastic model is written in a state-space formulation suitable for model reductions and control synthesis. A linear model of a single blade is used to design a Linear-Quadratic-Gaussian regulator on its root-bending moments, which is finally shown to provide load reductions of about 20% in closed-loop on the full wind turbine non-linear aeroelastic model

Sex Differences in the Quality of Diabetes Care in the Netherlands (ZODIAC-45)

OBJECTIVE:Our aim was to investigate whether trends in quality of diabetes care differ between sexes in the Netherlands from 1998 till 2013. RESEARCH DESIGN AND METHODS:In this prospective observational cohort study quality of care was measured using process and outcome measures in patients with type 2 diabetes in primary care. Trend and absolute differences between sexes were investigated for patients 53 mmol/mol; this decreased to approximately 29% in both sexes in 2013. Patients having a systolic blood pressure >140 mmHg decreased from 70% to 42%, and from 80% to 40% in men and women 20% over 10 years decreased from 15% to 3% in men and from 18% to 3% in women. CONCLUSIONS:Quality of diabetes care has improved considerably in the period 1998-2013 in both sexes. Possibly relevant trend differences between sexes were observed for HbA1c, systolic blood pressure, BMI and smoking. The predicted mortality risk decreased over time in both sexes. Except for BMI in both age groups and systolic blood pressure in patients ≥75 years, no evident poorer risk factor control in women compared to men was found at the end of the study period

Clinical Outcome and Morphologic Analysis after Endovascular Aneurysm Repair Using the Excluder Endograft

OBJECTIVE: Long-term follow-up after endovascular aneurysm repair (EVAR) is very scarce, and doubt remains regarding the durability of these procedures. We designed a retrospective cohort study to assess long-term clinical outcome and morphologic changes in patients with abdominal aortic aneurysms (AAAs) treated by EVAR using the Excluder endoprosthesis (W. L. Gore and Associates, Flagstaff, Ariz). METHODS: From 2000 to 2007, 179 patients underwent EVAR in a tertiary institution. Clinical data were retrieved from a prospective database. All patients treated with the Excluder endoprosthesis were included. Computed tomography angiography (CTA) scans were retrospectively analyzed preoperatively, at 30 days, and at the last follow-up using dedicated tridimensional reconstruction software. For patients with complications, all remaining CTAs were also analyzed. The primary end point was clinical success. Secondary end points were freedom from reintervention, sac growth, types I and III endoleak, migration, conversion to open repair, and AAA-related death or rupture. Neck dilatation, renal function, and overall survival were also analyzed. RESULTS: Included were 144 patients (88.2% men; mean age, 71.6 years). Aneurysms were ruptured in 4.9%. American Society of Anesthesiologists classification was III/IV in 61.8%. No patients were lost during a median follow-up of 5.0 years (interquartile range, 3.1-6.4; maximum, 11.2 years). Two patients died of medical complications ≤ 30 days after EVAR. The estimated primary clinical success rates at 5 and 10 years were 63.5% and 41.1%, and secondary clinical success rates were 78.3% and 58.3%, respectively. Sac growth was observed in 37 of 142 patients (26.1%). Cox regression showed type I endoleak during follow-up (hazard ratio, 3.74; P = .008), original design model (hazard ratio, 3.85; P = .001), and preoperative neck diameter (1.27 per mm increase, P = .006) were determinants of sac growth. Secondary interventions were required in 32 patients (22.5%). The estimated 10-year rate of AAA-related death or rupture was 2.1%. Overall life expectancy after AAA repair was 6.8 years. CONCLUSIONS: EVAR using the Excluder endoprosthesis provides a safe and lasting treatment for AAA, despite the need for maintained surveillance and secondary interventions. At up to 11 years, the risk of AAA-related death or postimplantation rupture is remarkably low. The incidences of postimplantation sac growth and secondary intervention were greatly reduced after the introduction of the low-permeability design in 2004

Homotopy types of stabilizers and orbits of Morse functions on surfaces

Let $M$ be a smooth compact surface, orientable or not, with boundary or without it, $P$ either the real line $R^1$ or the circle $S^1$, and $Diff(M)$ the group of diffeomorphisms of $M$ acting on $C^{\infty}(M,P)$ by the rule $h\cdot f\mapsto f \circ h^{-1}$, where $h\in Diff(M)$ and $f \in C^{\infty}(M,P)$. Let $f:M \to P$ be a Morse function and $O(f)$ be the orbit of $f$ under this action. We prove that $\pi_k O(f)=\pi_k M$ for $k\geq 3$, and $\pi_2 O(f)=0$ except for few cases. In particular, $O(f)$ is aspherical, provided so is $M$. Moreover, $\pi_1 O(f)$ is an extension of a finitely generated free abelian group with a (finite) subgroup of the group of automorphisms of the Reeb graph of $f$. We also give a complete proof of the fact that the orbit $O(f)$ is tame Frechet submanifold of $C^{\infty}(M,P)$ of finite codimension, and that the projection $Diff(M) \to O(f)$ is a principal locally trivial $S(f)$-fibration.Comment: 49 pages, 8 figures. This version includes the proof of the fact that the orbits of a finite codimension of tame action of tame Lie group on tame Frechet manifold is a tame Frechet manifold itsel

General relativistic corrections to the Sagnac effect

The difference in travel time of corotating and counter-rotating light waves in the field of a central massive and spinning body is studied. The corrections to the special relativistic formula are worked out in a Kerr field. Estimation of numeric values for the Earth and satellites in orbit around it show that a direct measurement is in the order of concrete possibilities.Comment: REVTex, accepted for publication on Phys. Rev.

Estimation of biological chromophores using diffuse optical spectroscopy: benefit of extending the UV-VIS wavelength range to include 1000 to 1600 nm

With an optical fiber probe, we acquired spectra from swine tissue between 500 and 1600 nm by combining a silicon and an InGaAs spectrometer. The concentrations of the biological chromophores were estimated by fitting a mathematical model derived from diffusion theory. The advantage of our technique relative to those presented in previous studies is that we extended the commonly-used wavelength ranges of 500 and 1000 nm to include the range of 1000 to 1600 nm, where additional water and lipid absorption features exist. Hence, a more accurate estimation of these two chromophores is expected when spectra are fitted between 500 and 1600 nm than between 500 and 1000 nm. When extending the UV-VIS wavelength range, the estimated total amount of chromophores approached 100% of the total as present in the probed volume. The confidence levels of the water and lipid related parameters increases by a factor of four

Contact force sensing in ablation of ventricular arrhythmias using a 56-hole open-irrigation catheter: a propensity-matched analysis.

PURPOSE: The effect of adding contact force (CF) sensing to 56-hole tip irrigation in ventricular arrhythmia (VA) ablation has not been previously studied. We aimed to compare outcomes with and without CF sensing in VA ablation using a 56-hole radiofrequency (RF) catheter. METHODS: A total of 164 patients who underwent first-time VA ablation using Thermocool SmartTouch Surround Flow (TC-STSF) catheter (Biosense-Webster, Diamond Bar, CA, USA) were propensity-matched in a 1:1 fashion to 164 patients who had first-time ablation using Thermocool Surround Flow (TC-SF) catheter. Patients were matched for age, gender, cardiac aetiology, ejection fraction and approach. Acute success, complications and long-term follow-up were compared. RESULTS: There was no difference between procedures utilising either TC-SF or TC-STSF in acute success (TC-SF: 134/164 (82%), TC-STSF: 141/164 (86%), p = 0.3), complications (TC-SF: 11/164 (6.7%), TC-STSF: 11/164 (6.7%), p = 1.0) or VA-free survival (TC-SF: mean arrhythmia-free survival time = 5.9 years, 95% CI = 5.4-6.4, TC-STSF: mean = 3.2 years, 95% CI = 3-3.5, log-rank p = 0.74). Fluoroscopy time was longer in normal hearts with TC-SF (19 min, IQR: 14-30) than TC-STSF (14 min, IQR: 8-25; p = 0.04). CONCLUSION: Both TC-SF and TC-STSF catheters are safe and effective in treating VAs. The use of CF sensing catheters did not improve safety or acute and long-term outcomes, but reduced fluoroscopy time in normal heart VA

Borderline Aggregation Kinetics in ``Dry'' and ``Wet'' Environments

We investigate the kinetics of constant-kernel aggregation which is augmented by either: (a) evaporation of monomers from finite-mass clusters, or (b) continuous cluster growth -- \ie, condensation. The rate equations for these two processes are analyzed using both exact and asymptotic methods. In aggregation-evaporation, if the evaporation is mass conserving, \ie, the monomers which evaporate remain in the system and continue to be reactive, the competition between evaporation and aggregation leads to several asymptotic outcomes. For weak evaporation, the kinetics is similar to that of aggregation with no evaporation, while equilibrium is quickly reached in the opposite case. At a critical evaporation rate, the cluster mass distribution decays as $k^{-5/2}$, where $k$ is the mass, while the typical cluster mass grows with time as $t^{2/3}$. In aggregation-condensation, we consider the process with a growth rate for clusters of mass $k$, $L_k$, which is: (i) independent of $k$, (ii) proportional to $k$, and (iii) proportional to $k^\mu$, with $0<\mu<1$. In the first case, the mass distribution attains a conventional scaling form, but with the typical cluster mass growing as $t\ln t$. When $L_k\propto k$, the typical mass grows exponentially in time, while the mass distribution again scales. In the intermediate case of $L_k\propto k^\mu$, scaling generally applies, with the typical mass growing as $t^{1/(1-\mu)}$. We also give an exact solution for the linear growth model, $L_k\propto k$, in one dimension.Comment: plain TeX, 17 pages, no figures, macro file prepende

Unicyclic Components in Random Graphs

The distribution of unicyclic components in a random graph is obtained analytically. The number of unicyclic components of a given size approaches a self-similar form in the vicinity of the gelation transition. At the gelation point, this distribution decays algebraically, U_k ~ 1/(4k) for k>>1. As a result, the total number of unicyclic components grows logarithmically with the system size.Comment: 4 pages, 2 figure

Kinetic Anomalies in Addition-Aggregation Processes

We investigate irreversible aggregation in which monomer-monomer, monomer-cluster, and cluster-cluster reactions occur with constant but distinct rates K_{MM}, K_{MC}, and K_{CC}, respectively. The dynamics crucially depends on the ratio gamma=K_{CC}/K_{MC} and secondarily on epsilon=K_{MM}/K_{MC}. For epsilon=0 and gamma<2, there is conventional scaling in the long-time limit, with a single mass scale that grows linearly in time. For gamma >= 2, there is unusual behavior in which the concentration of clusters of mass k, c_k decays as a stretched exponential in time within a boundary layer k<k* propto t^{1-2/gamma} (k* propto ln t for gamma=2), while c_k propto t^{-2} in the bulk region k>k*. When epsilon>0, analogous behaviors emerge for gamma<2 and gamma >= 2.Comment: 6 pages, 2 column revtex4 format, for submission to J. Phys.