2,136 research outputs found

    Political favoritism in Chinaā€™s capital markets and its effect on city sizes

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    This paper examines political favoritism of cites in national capital markets and the effect of that favoritism on city sizes. The paper estimates the city-by-city variation in the prices of capital across cities in China from 1998 to 2007. It relates how the prices facing the highest order political units and overall cross-city price dispersion change with changes in national policy and leadership. The effect of capital market favoritism on city growth after the national relaxation of migration restrictions in the early 2000ā€™s is investigated. The elasticity of the city growth rate with respect to the price of capital is estimated to be āˆ’āˆ’0.07 in the OLS approach and āˆ’āˆ’0.12 in the IV approach

    Continuing the Development of Anaplastic Thyroid Cancer PDXs

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    https://openworks.mdanderson.org/sumexp22/1031/thumbnail.jp

    Quantum correlation in three-qubit Heisenberg model with Dzyaloshinskii-Moriya interaction

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    We investigate the pairwise thermal quantum discord in a three-qubit XXZ model with Dzyaloshinskii-Moriya (DM) interaction. We find that the DM interaction can increase quantum discord to a fixed value in the anti- ferromagnetic system, but decreases quantum discord to a minimum first, then increases it to a fixed value in the ferromagnetic system. Abrupt change of quantum discord is observed, which indicates the abrupt change of groundstate. Dynamics of pairwise thermal quantum discord is also considered. We show that thermal discord vanishes in asymptotic limit regardless of its initial values, while thermal entanglement suddenly disappears at finite time.Comment: 6 pages, 6 figure

    Assessing Public Health Burden Associated with Exposure to Ambient Black Carbon in the United States

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    Black carbon (BC) is a significant component of fine particulate matter (PM2.5) air pollution, which has been linked to a series of adverse health effects, in particular premature mortality. Recent scientific research indicates that BC also plays an important role in climate change. Therefore, controlling black carbon emissions provides an opportunity for a double dividend. This study quantifies the national burden of mortality and morbidity attributable to exposure to ambient BC in the United States (US). We use GEOSā€“Chem, a global 3-D model of atmospheric composition to estimate the 2010 annual average BC levels at 0.5 x 0.667Ā° resolution, and then re-grid to 12-km grid resolution across the continental US. Using PM2.5 mortality risk coefficient drawn from the American Cancer Society cohort study, the numbers of deaths due to BC exposure were estimated for each 12-km grid, and then aggregated to the county, state and national level. Given evidence that BC particles may pose a greater risk on human health than other components of PM2.5, we also conducted sensitivity analysis using BC-specific risk coefficients drawn from recent literature. We estimated approximately 14,000 deaths to result from the 2010 BC levels, and hundreds of thousands of illness cases, ranging from hospitalizations and emergency department visits to minor respiratory symptoms. Sensitivity analysis indicates that the total BC-related mortality could be even significantly larger than the above mortality estimate. Our findings indicate that controlling BC emissions would have substantial benefits for public health in the US

    Assessing Public Health Burden Associated with Exposure to Ambient Black Carbon in the United States

    Get PDF
    Black carbon (BC) is a significant component of fine particulate matter (PM2.5) air pollution, which has been linked to a series of adverse health effects, in particular premature mortality. Recent scientific research indicates that BC also plays an important role in climate change. Therefore, controlling black carbon emissions provides an opportunity for a double dividend. This study quantifies the national burden of mortality and morbidity attributable to exposure to ambient BC in the United States (US). We use GEOSā€“Chem, a global 3-D model of atmospheric composition to estimate the 2010 annual average BC levels at 0.5 x 0.667Ā° resolution, and then re-grid to 12-km grid resolution across the continental US. Using PM2.5 mortality risk coefficient drawn from the American Cancer Society cohort study, the numbers of deaths due to BC exposure were estimated for each 12-km grid, and then aggregated to the county, state and national level. Given evidence that BC particles may pose a greater risk on human health than other components of PM2.5, we also conducted sensitivity analysis using BC-specific risk coefficients drawn from recent literature. We estimated approximately 14,000 deaths to result from the 2010 BC levels, and hundreds of thousands of illness cases, ranging from hospitalizations and emergency department visits to minor respiratory symptoms. Sensitivity analysis indicates that the total BC-related mortality could be even significantly larger than the above mortality estimate. Our findings indicate that controlling BC emissions would have substantial benefits for public health in the US

    Nicotinic Receptor Subtype-Selective Circuit Patterns in the Subthalamic Nucleus

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    The glutamatergic subthalamic nucleus (STN) exerts control over motor output through nuclei of the basal ganglia. High-frequency electrical stimuli in the STN effectively alleviate motor symptoms in movement disorders, and cholinergic stimulation boosts this effect. To gain knowledge about the mechanisms of cholinergic modulation in the STN, we studied cellular and circuit aspects of nicotinic acetylcholine receptors (nAChRs) in mouse STN. We discovered two largely divergent microcircuits in the STN; these are regulated in part by either Ī±4Ī²2 or Ī±7 nAChRs. STN neurons containing Ī±4Ī²2 nAChRs (Ī±4Ī²2 neurons) received more glutamatergic inputs, and preferentially innervated GABAergic neurons in the substantia nigra pars reticulata. In contrast, STN neurons containing Ī±7 nAChRs (Ī±7 neurons) received more GABAergic inputs, and preferentially innervated dopaminergic neurons in the substantia nigra pars compacta. Interestingly, local electrical stimuli excited a majority (79%) of Ī±4Ī²2 neurons but exerted strong inhibition in 58% of Ī±7 neurons, indicating an additional diversity of STN neurons: responses to electrical stimulation. Chronic exposure to nicotine selectively affects Ī±4Ī²2 nAChRs in STN: this treatment increased the number of Ī±4Ī²2 neurons, upregulated Ī±4-containing nAChR number and sensitivity, and enhanced the basal firing rate of Ī±4Ī²2 neurons both ex vivo and in vivo. Thus, chronic nicotine enhances the function of the microcircuit involving Ī±4Ī²2 nAChRs. This indicates chronic exposure to nicotinic agonist as a potential pharmacological intervention to alter selectively the balance between these two microcircuits, and may provide a means to inhibit substantia nigra dopaminergic neurons

    A decade of Australian general practice activity 2001ā€“02 to 2010ā€“11

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    In the last decade, the opening and the bigger exposure of Azores Autonomic Region in the media, as well the assumption of the importance of tourism to the regional economy by the local government, introduced the planning of this sector in those islands. Even if all regions have specific features as the main touristic Portuguese regions such as Algarve, Madeira and Lisboa, the Azores product - Natural landscape - is different from the all the rest. Its difference and specification is directed to niche markets, which means not to attract the consumer populations of the most searched touristic product - Sun and beach. Due the fragility and weak capacity of the Azorean touristic product renovation, but still with the necessity of economical income, itā€™s essential the non-allowance of tourist masses but at- tract a highly economic value and academic instructed tourist type. The Scandinavian population has been one of the bets for a sustainable tourism in Azores, and Finland one of the some questions: Is this a correct bet? What can Azores offer? What are Finnish searching in their vacations periods? To answer those questions a bibliographic search and an inquiry were Azores offer it Ģs pretended

    General practice activity in Australia 2014ā€“15

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    This is the 17th annual report and the 38th book in the General Practice Series from the BEACH (Bettering the Evaluation and Care of Health) program, a continuous national study of general practice activity in Australia.Australian Government Department of Health, AstraZeneca Pty Ltd (Australia), Novartis Pharmaceuticals Australia Pty Ltd, bioCSL (Australia) Pty Ltd, AbbVie Pty Ltd, Australian Government Department of Veterans' Affair
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